Results 211 to 220 of about 82,562 (259)

Structure and function of lipopolysaccharides

Microbes and Infection, 2002
The lipopolysaccharides of Gram-negative bacteria have a profound effect on the mammalian immune system and are of great significance in the pathophysiology of many disease processes. Consideration is given in this review to the relationship between structure and function of these lipopolysaccharides.
Clett Erridge, Elliott Bennett-Guerrero, Ian R Poxton   +2 more
exaly   +4 more sources

Lipopolysaccharide-Dependent and Lipopolysaccharide-Independent Pathways of Monocyte Desensitisation to Lipopolysaccharides

Journal of Leukocyte Biology, 1991
Abstract The present study demonstrates that with time in culture blood monocytes (MO) lose their ability to express procoagulant activity (PCA) and secrete tumor necrosis factor-alpha (TNFα) in culture medium in response to lipopolysaccharide (LPS) stimulation.
A Y, Annenkov, F S, Baranova
openaire   +2 more sources

LIPOPOLYSACCHARIDE RECOGNITION, CD14, AND LIPOPOLYSACCHARIDE RECEPTORS

Infectious Disease Clinics of North America, 1999
The ability of a host to sense invasion by a pathogenic organism, and to respond appropriately to control infection, is paramount to survival. To that end, an array of receptors and binding proteins has evolved as part of the innate immune system to detect Gram-negative bacteria.
R R, Ingalls, H, Heine, E, Lien, A, Yoshimura, D, Golenbock   +4 more
openaire   +2 more sources

Antibodies to lipopolysaccharide

Journal of Immunological Methods, 1995
Lipopolysaccharides (LPS) are indispensable structural components of the Gram-negative bacterial outer membrane and are major determinants of virulence in pathogenic species. In the infected host LPS is better known as endotoxin where it acts as a potent stimulator of the inflammatory response.
openaire   +2 more sources

PATHOBIOLOGY OF LIPOPOLYSACCHARIDE

Journal of Toxicology and Environmental Health, 1997
Lipopolysaccharide is a component of the gram-negative bacterial cell wall that is responsible for 25,000-50,000 deaths in the United States each year. The sequelae of gram-negative infection and septicemia leading to death include fever, hypotension with inadequate tissue perfusion, and disseminated intravascular coagulation.
openaire   +2 more sources

Lipopolysaccharides ofShigella sonnei

Applied Biochemistry and Microbiology, 2000
Immunobiological properties of native lipopolysaccharides (LPS) from virulent and avirulent strains of Shigella sonnei bacteria (LPS-V and LPS-A, respectively) were studied. In avirulent bacteria, LPS-V induced immunosuppressive activity specific of the virulent strain. LPS of the avirulent strain, whereas LPS-A lacked this property.
E V, Borisova, V A, Borisov
openaire   +2 more sources

A Lipopolysaccharide Antigen of the Treponema

Nature, 1958
IMMUNOCHEMICAL studies carried out by D'Alessandro et al. 1 on a non-pathogenic, culturable treponeme, the so-called Reiter treponeme, revealed the presence of four antigenic components: (1) a thermolabile protein; (2) a specific, thermostable antigen with polysaccharide characteristics; (3) a lipoid, corresponding to the ubiquitous lipidic antigen ...
G, D'ALESSANDRO, C, DEL CARPIO
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Lipopolysaccharide of Coxiella burnetii

2012
A lipopolysaccharide (LPS) is considered to be one of the major determinants of virulence expression and infection of virulent Coxiella burnetii. The LPSs from virulent phase I (LPS I) and from avirulent phase II (LPS II) bacteria were investigated for their chemical composition, structure and biological properties.
Craig T, Narasaki, Rudolf, Toman
openaire   +2 more sources

Structure of bacterial lipopolysaccharides

Carbohydrate Research, 2003
Bacterial lipopolysaccharides are the major components of the outer surface of Gram-negative bacteria They are often of interest in medicine for their immunomodulatory properties. In small amounts they can be beneficial, but in larger amounts they may cause endotoxic shock.
Martine, Caroff, Doris, Karibian
openaire   +2 more sources