Results 101 to 110 of about 826,002 (242)

The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in Aspergillus fumigatus sensitized mice. [PDF]

open access: yes, 2012
BackgroundLipoprotein-associated phospholipase A2 (Lp-PLA2)/platelet-activating factor acetylhydrolase (PAF-AH) has been implicated in the pathogenesis of cardiovascular disease.
Fehrenbach, Melane L   +8 more
core   +2 more sources

Three arginine residues in apolipoprotein A-I are critical for activation of lecithin:cholesterol acyltransferase

open access: yesJournal of Lipid Research, 2001
Previous studies have suggested that the helical repeat formed by residues 143–164 of apolipoprotein A-I (apoA-I) contributes to lecithin:cholesterol acyltransferase (LCAT) activation.
Stein Roosbeek   +10 more
doaj   +1 more source

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

open access: yes, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin   +7 more
core   +1 more source

ApoA-I-Mediated Lipoprotein Remodeling Monitored with a Fluorescent Phospholipid

open access: yesBiology, 2019
We describe simple, sensitive and robust methods to monitor lipoprotein remodeling and cholesterol and apolipoprotein exchange, using fluorescent Lissamine Rhodamine B head-group tagged phosphatidylethanolamine (*PE) as a lipoprotein reference marker ...
Edward B. Neufeld   +11 more
doaj   +1 more source

Electronegative LDLs from familial hypercholesterolemic patients are physicochemically heterogeneous but uniformly proapoptotic

open access: yesJournal of Lipid Research, 2007
A highly electronegative fraction of human plasma LDLs, designated L5, has distinctive biological activity that includes induction of apoptosis in bovine aortic endothelial cells (BAECs).
Hsin-hung Chen   +7 more
doaj   +1 more source

Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]

open access: yes, 2020
"Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
core   +1 more source

Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes

open access: yesJournal of Lipid Research, 2004
Previous reports attributed cholesteryl ester transfer protein (CETP)-mediated HDL cholesteryl ester (CE) selective uptake to the CETP-mediated transfer of CE from HDL to newly secreted apolipoprotein B-containing lipoproteins, which are then ...
Gerard Vassiliou, Ruth McPherson
doaj   +1 more source

Assessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia [PDF]

open access: yes, 2017
Numerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke.
AlSulaiman, Wafa
core  

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