Results 111 to 120 of about 864,255 (364)

Evolving lipoprotein risk factors: lipoprotein(a) and oxidized low-density lipoprotein [PDF]

open access: yesClinical Chemistry, 1998
Abstract Cardiovascular disease is the leading cause of morbidity and mortality in Westernized populations. Evolving lipoprotein risk factors include LDL oxidation and lipoprotein(a) [lp(a)]. Several lines of evidence support a role for oxidatively modified LDL in atherogenesis and its in vivo existence.
openaire   +3 more sources

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

Cholesteryl ester transfer protein (CETP) mRNA abundance in human adipose tissue: relationship to cell size and membrane cholesterol content.

open access: yesJournal of Lipid Research, 1995
Cholesteryl ester transfer protein (CETP) has a well-defined role in plasma neutral lipid transport. CETP synthesized by human adipose tissue may contribute to the plasma CETP pool. CETP mRNA abundance increases in subcutaneous adipose tissue in response
T Radeau   +5 more
doaj  

Lipid Metabolism and Comparative Genomics [PDF]

open access: yes, 2006
Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette   +5 more
core  

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

open access: yesEuropean Heart Journal, 2011
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically appraise evidence for elevated levels of triglyceride-rich lipoproteins (
M. Chapman   +18 more
semanticscholar   +1 more source

Nanopore‐Functionalized Hybrid Lipid‐Block Copolymer Membranes Allow Efficient Single‐Molecule Sampling and Stable Sensing of Human Serum

open access: yesAdvanced Materials, EarlyView.
Biological nanopores are highly promising tools for single‐molecule biosensors, but the fragile supporting lipid membranes is a major bottleneck. An alternative hybrid membrane is presented, comprising phospholipids and block co‐polymers, that can be functionalized by a broad variety of nanopores for single‐molecule sensing.
Edo Vreeker   +6 more
wiley   +1 more source

Expression and secretion of rabbit plasma cholesteryl ester transfer protein by Pichia pastoris

open access: yesJournal of Lipid Research, 1996
The rabbit cholesteryl ester transfer protein (CETP) was expressed in the methylotrophic yeast Pichia pastoris by introducing the CETP cDNA under the control of the methanol-inducible alcohol oxidase promoter.
H Kotake   +5 more
doaj  

Carotid intima media thickness and low high-density lipoprotein (HDL) in South Asian immigrants: could dysfunctional HDL be the missing link? [PDF]

open access: yes, 2014
IntroductionSouth Asian immigrants (SAIs) in the US exhibit higher prevalence of coronary artery disease (CAD) and its risk factors compared with other ethnic populations.
Dodani, Sunita   +3 more
core   +2 more sources

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

Phosphatidylcholine biosynthesis is required for secretion of truncated apolipoprotein Bs from McArdle RH7777 cells only when a neutral lipid core is formed

open access: yesJournal of Lipid Research, 1997
Decreased phosphatidylcholine biosynthesis inhibits the secretion of very low density lipoproteins from hepatocytes (Yao, Z. and D. E. Vance. 1988. J. Biol. Chem. 263: 2998-3004).
P S Vermeulen   +3 more
doaj  

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