Results 111 to 120 of about 999,472 (383)
Expression and secretion of rabbit plasma cholesteryl ester transfer protein by Pichia pastoris
Journal of Lipid Research, 1996 The rabbit cholesteryl ester transfer protein (CETP) was expressed in the methylotrophic yeast Pichia pastoris by introducing the CETP cDNA under the control of the methanol-inducible alcohol oxidase promoter.
H Kotake +5 more
doaj
Pathways-driven Sparse Regression Identifies Pathways and Genes Associated with High-density Lipoprotein Cholesterol in Two Asian Cohorts [PDF]
arXiv, 2013 Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of interest. In a second step, important single nucleotide
arxiv
Albumin Corona Overturns Long‐Acting Behaviors of Myristic Acid‐Conjugated Quetiapine Nanosuspension
Advanced Healthcare Materials, EarlyView.Albumin corona alters surface properties and enhances colloidal stability by overturning pH responsiveness and nano‐aggregation behaviors of long‐acting myristic acid‐conjugated quetiapine nanosuspensions (QMN), resulting in accelerated in vitro and in vivo drug release.
Hy Dinh Nguyen +2 more
wiley +1 more source
Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. [PDF]
, 2018 Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell (HSPC) maintenance.
Han, Tianxu +10 more
core +2 more sources
Journal of Lipid Research, 1995 Cholesteryl ester transfer protein (CETP) has a well-defined role in plasma neutral lipid transport. CETP synthesized by human adipose tissue may contribute to the plasma CETP pool. CETP mRNA abundance increases in subcutaneous adipose tissue in response
T Radeau +5 more
doaj
Advanced Materials, EarlyView.A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen +7 more
wiley +1 more source
Coronary heart disease risks associated with high levels of HDL cholesterol. [PDF]
, 2014 BackgroundThe association between high-density lipoprotein cholesterol (HDL-C) and coronary heart disease (CHD) events is not well described in individuals with very high levels of HDL-C (>80 mg/dL).Methods and resultsUsing pooled data from 6 ...
Criqui, Michael H +6 more
core +2 more sources
Journal of Lipid Research, 1996 Mutations in the gene for the low density lipoprotein (LDL) receptor have been identified in 15 patients with homozygous familial hypercholesterolemia (FH).
J C Webb +6 more
doaj
Two Robust Tools for Inference about Causal Effects with Invalid Instruments [PDF]
arXiv, 2020 Instrumental variables have been widely used to estimate the causal effect of a treatment on an outcome. Existing confidence intervals for causal effects based on instrumental variables assume that all of the putative instrumental variables are valid; a valid instrumental variable is a variable that affects the outcome only by affecting the treatment ...
arxiv
Proceedings of the National Academy of Sciences of the United States of America, 1984 Low density lipoprotein (LDL) incubated with cultured endothelial cells from rabbit aorta or human umbilical vein is altered in several ways (EC-modified): (i) It is degraded by macrophages much faster than LDL similarly incubated in the absence of cells
U. Steinbrecher +4 more
semanticscholar +1 more source