Results 121 to 130 of about 864,255 (364)

Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]

, 2014
Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce, Huang, Jincui, Lebrilla, Carlito B, Lee, Hyeyoung, Rivera, Nancy, Smilowitz, Jennifer T, Zivkovic, Angela M   +6 more
core   +1 more source

Pathways-driven Sparse Regression Identifies Pathways and Genes Associated with High-density Lipoprotein Cholesterol in Two Asian Cohorts [PDF]

arXiv, 2013
Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of interest. In a second step, important single nucleotide
arxiv  

Regression with a right-censored predictor, using inverse probability weighting methods [PDF]

arXiv, 2020
In a longitudinal study, measures of key variables might be incomplete or partially recorded due to drop-out, loss to follow-up, or early termination of the study occurring before the advent of the event of interest. In this paper, we focus primarily on the implementation of a regression model with a randomly censored predictor.
arxiv  

Platelets and Lipoproteins

Platelets, 1994
Sir, Malle and Sattler's excellent review links lipids with the release of serotonin from platelets.' It is therefore, of interest that correlations between serum cholesterol and intraplatelet/plasma serotonin concentrations have been reported.'-* Moreover, reducing serum cholesterol and low density lipoprotein (LDL) concentrations normalised ...
A F Wider, D. P. Mikhailidis, M. A. Barradas, J. Y. Jeremy   +3 more
openaire   +3 more sources

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Apolipoprotein distribution in human lipoproteins separated by polyacrylamide gradient gel electrophoresis.

Journal of Lipid Research, 1988
The heterogeneity of serum lipoproteins (excluding very low density (VLDL) and intermediate density (IDL) lipoproteins) and that of lipoproteins secreted by HepG2 cells has been studied by immunoblot analysis of the apolipoprotein composition of the ...
C A Vézina, R W Milne, P K Weech, Y L Marcel   +3 more
doaj  

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

Proceedings of the National Academy of Sciences of the United States of America, 1984
Low density lipoprotein (LDL) incubated with cultured endothelial cells from rabbit aorta or human umbilical vein is altered in several ways (EC-modified): (i) It is degraded by macrophages much faster than LDL similarly incubated in the absence of cells
U. Steinbrecher, S. Parthasarathy, D. Leake, J. Witztum, D. Steinberg   +4 more
semanticscholar   +1 more source

The Antiviral Efficacy and Safety of Azvudine in Hospitalized SARS‐CoV‐2 Infected Patients with Liver Diseases Based on a Multicenter, Retrospective Cohort Study

Advanced Science, EarlyView.
Azvudine shows benefits in reducing all‐cause mortality in hospitalized SARS‐CoV‐2 infected patients and liver diseases. COVID‐19 patients with kidney disease and without autoimmune diseases show a preference for azvudine. Azvudine may be a promising antiviral agent for treating COVID‐19 concomitant with liver diseases.
Junyi Sun, Mengzhao Yang, Guanyue Su, Ling Wang, Xiaobo Hu, Yongjian Zhou, Guangying Cui, Guowu Qian, Yiqiang Yuan, Xinjun Hu, Silin Li, Hong Luo, Shixi Zhang, Guangming Li, Donghua Zhang, Guotao Li, Ming Cheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Protocol for the study of the metabolism of retinyl esters in plasma lipoproteins during postprandial lipemia.

Journal of Lipid Research, 1992
An efficient protocol is described for the study of the kinetics of retinyl esters in whole plasma and several lipoprotein fractions following the consumption of an oral fat load containing vitamin A (retinol).
G Ruotolo, H Zhang, V Bentsianov, NA Le
doaj  

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source