Results 131 to 140 of about 999,472 (383)

A Latent Mixture Model for Heterogeneous Causal Mechanisms in Mendelian Randomization [PDF]

open access: yesarXiv, 2020
Mendelian Randomization (MR) is a popular method in epidemiology and genetics that uses genetic variation as instrumental variables for causal inference. Existing MR methods usually assume most genetic variants are valid instrumental variables that identify a common causal effect.
arxiv  

Role of oxidized low density lipoprotein in atherogenesis.

open access: yesJournal of Clinical Investigation, 1991
Evidence to support an important role of oxidative modification in mediating the atherogenicity of LDL continues to grow. New hypotheses suggest mechanisms by which Ox-LDL or products of Ox-LDL can affect many components of the atherogenic process ...
J. Witztum, D. Steinberg
semanticscholar   +1 more source

Correlative Super‐Resolution Imaging of Cellular Nanopores Facilitated by Transparent Polymer Waveguide Chips

open access: yesAdvanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
Correlative super‐resolution optical imaging of the ultrastructure of rat liver sinusoidal endothelial cells (LSECs) across a large field of view (FOV) with 3D structured illumination microscopy (3D‐SIM) and single‐molecule localization microscopy (SMLM), facilitated by a transparent polymer photonic waveguide chip, is presented.
Surjendu Bikash Dutta   +9 more
wiley   +1 more source

Concentrations and compositions of plasma lipoprotein subfractions of Lpb5-Lpu1 homozygous and heterozygous swine with hypercholesterolemia.

open access: yesJournal of Lipid Research, 1990
Pigs with two mutant epitopes, Lpb5 of apolipoprotein B (apoB) and Lpu1 of a yet undefined apolipoprotein, specified by a haplotype Lpb5-Lpu1 and fed a cholesterol-free low fat diet show hypercholesterolemia.
DM Lee, T Mok, J Hasler-Rapacz, J Rapacz
doaj  

Low density lipoprotein undergoes oxidative modification in vivo.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1989
It has been proposed that low density lipoprotein (LDL) must undergo oxidative modification before it can give rise to foam cells, the key component of the fatty streak lesion of atherosclerosis.
W. Palinski   +9 more
semanticscholar   +1 more source

Nanotherapy for Neural Retinal Regeneration

open access: yesAdvanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu   +11 more
wiley   +1 more source

Lipid Metabolism and Comparative Genomics [PDF]

open access: yes, 2006
Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette   +5 more
core  

Monomethylethanolamine reduces plasma triacylglycerols and apolipoprotein B and increases apolipoprotein A-I rats without induction of fatty liver

open access: yesJournal of Lipid Research, 1996
Monomethylethanolamine (MME) inhibits very low density lipoprotein (VLDL) secretion from cultured rat hepatocytes by disruption of translocation of apolipoprotein (apo) B across the endoplasmic reticulum membrane (A. E. Rusiñol, E. Y. W. Chan and J.
A E Rusiñol   +3 more
doaj  

Structured functional regression models for high-dimensional spatial spectroscopy data [PDF]

open access: yesarXiv, 2013
Modeling and analysis of spectroscopy data is an active area of research with applications to chemistry and biology. This paper focuses on analyzing Raman spectra obtained from a bone fracture healing experiment, although the functional regression model for predicting a scalar response from high-dimensional tensors can be applied to any spectroscopy ...
arxiv  

Home - About - Disclaimer - Privacy