Results 131 to 140 of about 849,886 (339)

Classification and Prediction of Low-Density Lipoprotein Cholesterol LDL-C in The Palestinian Patients Using Machine Learning Techniques

open access: bronze, 2021
Sanad Malaysha   +89 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

Serum lipid profiles in acute myocardial infarction patients in Gorgan [PDF]

open access: yes, 2012
Acute myocardial infarction is one of the important reasons of death and unhealthiness in the world. The present study was undertaken to investigate the changes in serum lipids and lipoproteins in patients with acute myocardial infarction. This study was
Marjani, A., Shirafkan, A., Zaker, F.
core  

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

open access: yesAdvanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher   +15 more
wiley   +1 more source

Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]

open access: yes, 2020
"Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
core   +1 more source

Lipoprotein-Associated Phospholipase A 2 Protein Expression in the Natural Progression of Human Coronary Atherosclerosis [PDF]

open access: bronze, 2006
Frank D. Kolodgie   +6 more
openalex   +1 more source

Lipoprotein-associated phospholipase A2 and carotid intima-media thickness in primary Sjögren syndrome

open access: diamond, 2021
Selcan Gültuna   +4 more
openalex   +2 more sources

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

open access: yesAdvanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li   +12 more
wiley   +1 more source

The Role of Lipoprotein (a) as a Marker of Residual Risk in Patients With Diabetes and Established Cardiovascular Disease on Optimal Medical Therapy: Post Hoc Analysis of ACCELERATE [PDF]

open access: bronze, 2019
Nishant Shah   +11 more
openalex   +1 more source

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