Results 171 to 180 of about 864,255 (364)
Contextualizing selection bias in Mendelian randomization: how bad is it likely to be? [PDF]
arXiv, 2018 Selection bias affects Mendelian randomization investigations when selection into the study sample depends on a collider between the genetic variant and confounders of the risk factor-outcome association. However, the relative importance of selection bias for Mendelian randomization compared to other potential biases is unclear.
arxiv
Advanced Science, EarlyView.Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang +15 more
wiley +1 more source
Journal of Lipid Research, 1991 We previously reported that the expression of an epitope of apolipoprotein B (apoB), mapped to the C-terminus and defined by antibody Bsol7, increased during Cu2(+)-mediated oxidation of isolated low density lipoprotein (LDL).
Z Zawadzki, RW Milne, YL Marcel
doaj
The Effects of Temulawak extract and Yoghurt on HDL-LDL mice blood exposed waste cooking oil [PDF]
, 2015 Using cooking oil repeatedly in processing the fried foods can cause health problems, especially cholesterol metabolism that affect levels of HDL, LDL, triglycerides and total cholesterol blood that can cause blockage of blood vessels leading
Alipin, Kartiawati +2 more
core
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
Advanced Science, EarlyView.The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari +20 more
wiley +1 more source
Journal of Lipid Research, 1988 We measured the amount of apoA-I in serum by isotope dilution, finding 1.33 mg/ml (standard deviation 0.177) in six normolipidemic, healthy subjects. We developed this method by adapting published techniques to purify apoA-I from 3 ml of serum in two ...
P K Weech, D Jewer, Y L Marcel
doaj
Advanced Science, EarlyView.Lipid content in medium high‐density lipoprotein (HDL) particles, particularly cholesteryl esters, is identified as causally protective of atherosclerosis, and further ASCVD. Evidence from multi‐omics layers of data consistently supports PSRC1 with therapeutic potential for coronary artery disease (CAD), but not ischemic stroke.
Yingmei Li +8 more
wiley +1 more source
Advanced Science, EarlyView.A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma +13 more
wiley +1 more source
Journal of Lipid Research, 1994 We have investigated the possible requirement of phosphatidylcholine for normal progression through the cell cycle of C3H/10T1/2 fibroblasts. Incubation of the cells in a medium with 0.5% serum synchronized the cells in the G0 stage of the cell cycle ...
F Tercé, H Brun, D E Vance
doaj