Immunochemical studies on human plasma lipoproteins [PDF]
Some years ago, a series of human serum lipoproteins, distinguishable by their hydrated densities and lipid-protein ratios were recognized and isolated by ultracentrifugal techniques (1).
Aladjem, Frederick+2 more
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Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children. [PDF]
BackgroundGlycosylation patterns of serum proteins, such as α1-acid glycoprotein, are modified during an acute phase reaction. The response of acute Kawasaki disease (KD) patients to IVIG treatment has been linked to sialic acid levels on native IgG ...
Burns, Jane C+8 more
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Apolipoprotein E (apoE), a 299 amino acid protein, is a ligand for the low density lipoprotein receptor (LDLr). It has been established that basic amino acids situated between apoE residues 136 and 150 participate in the interaction of apoE with the LDLr.
R Raffai+9 more
doaj +1 more source
Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study [PDF]
Objectives The interleukin-6 receptor (IL-6R) blocker tocilizumab (TCZ) reduces inflammatory disease activity in rheumatoid arthritis (RA) but elevates lipid concentrations in some patients.
Bathon, Joan M.+10 more
core +1 more source
Studies of the structure and function of apolipoprotein A-I (apoA-I) often require its purification by delipidation of high density lipoprotein isolated from large quantities of human plasma and separation of apoA-I from other plasma apolipoproteins.
L E Pyle+4 more
doaj +1 more source
Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis. [PDF]
BACKGROUND: Carotid intima-media thickness (CIMT), a subclinical measure of atherosclerosis, is associated with risk of coronary heart disease events. Statins reduce progression of CIMT and coronary heart disease risk in proportion to the reduction in ...
Baldassarre, Damiano+22 more
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Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo [PDF]
Lipoproteins are an important class of surface associated proteins that have diverse roles and frequently are involved in the virulence of bacterial pathogens.
A Bidossi+91 more
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Quantitation of plasma mevalonic acid using gas chromatography-electron capture mass spectrometry.
Circulating concentrations of mevalonic acid (MVA) change in parallel with, and may be used as a marker of cholesterol biosynthesis. Plasma MVA levels have been quantified using a sensitive and specific capillary gas chromatography-electron capture mass ...
A Scoppola+4 more
doaj +1 more source
Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]
The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW+8 more
core +1 more source
Probucol treatment results in an increase in plasma concentrations of cholesteryl ester transfer protein (CETP) which may account, in part, for the effects of this agent on plasma concentrations of HDL cholesterol. We have examined the mechanism by which
EM Quinet+5 more
doaj +1 more source