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Lipoprotein(a) : new insights into an atherogenic lipoprotein

The Clinical Investigator, 1994
Lipoprotein(a) constitutes a macromolecular complex in human plasma that combines structural features from the blood clotting and the lipoprotein systems. Aside from the discovery of lipoprotein(a) [Lp(a)] as a potential independent risk factor for premature cardiovascular disease its physiological role and activity remains obscure.
Bartens, Werner, Wanner, Christoph
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Lipoprotein(a)

JAMA
This JAMA Insights discusses lipoprotein(a), including factors associated with elevated lipoprotein(a) levels, how to manage them, and atherosclerotic cardiovascular disease risk.
Samia, Mora, Florian, Kronenberg
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Lipoprotein(a) and atherogenesis

Trends in Cardiovascular Medicine, 1994
Lipoprotein(a) is a major inherited risk factor for atherosclerosis. Many of its activities depend on its plasminlike component, apolipoprotein(a). In vitro studies suggest that apolipoprotein(a) could enhance lipid deposition through binding to sites in the vessel wall, interfere with fibrinolysis, and modulate smooth muscle cell activity.
Richard M. Lawn, Alexander C. Liu
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Lipoprotein(a) apheresis

Current Opinion in Lipidology, 2016
Purpose of review Currently, different methods for extracorporeal elimination of atherogenic apolipoprotein B100 containing lipoprotein particles are used in clinical practice. Most of them effectively remove both lipoprotein(a) [Lp(a)] and LDL.
Olga I. Afanasieva   +2 more
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Lipoproteins and coagulation

Perfusion, 1997
A broad range of molecular and cellular interactions contribute to various pathophysiological alterations in haemostasis. Recent studies have shown strong links between lipoproteins and coagulation factors. Findings suggest that lipoproteins play an important role in the fibrinolytic and thrombogenic mechanisms that influence the risks of patients in ...
Annette Basile-Borgia, John H. Abel
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High density lipoprotein and lipoprotein oxidation

Current Opinion in Lipidology, 1996
HDL protects LDL from oxidative damage known to contribute to the onset and progression of atherosclerosis. This antioxidant protection by HDL is mediated by intrinsic hydrolytic enzyme systems, by accelerated selective uptake of lipid peroxides from HDL and by antioxidant molecules.
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Lipoprotein Molecule or Lipoprotein Particle?

1978
May I wind up this Advanced Study Institute by sketching briefly what this course has meant at least as far as my judgement goes. Not that I believe to be a polyvalent expert on all topics presented but I do think it is my duty to outline the status of our knowledge and the avenues along which we should make progress.
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The Plasma Lipoproteins

1977
Publisher Summary Plasma lipoproteins are the macromolecular complexes with reproducible lipid-protein ratios and stability in aqueous solutions. This chapter describes the classification of the plasma lipoproteins, molecular properties of apolipoproteins, molecular organization of lipoprotein particles, and lipoprotein metabolism.
Brewer Hb, James C. Osborne
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The Mysteries Of Lipoprotein(a)

Science, 1989
Lipoprotein(a) [Lp(a)] is a macromolecular complex found in human plasma that combines structural elements from the lipoprotein and blood clotting systems and that is associated with premature coronary heart disease and stroke. It is assembled from low-density lipoprotein (LDL) and a large hydrophilic glycoprotein called apolipoprotein(a) [
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Glucagon and lipoproteins

Metabolism, 1976
HE HEPATIC PRODUCTION of lipoprotein is a complex phenomenon, involving a synchronous relationship between hepatic apoprotein synthesis, and the actual tipoprotein secretory event. A role for glucagon in modulating these events has been proposed.~ The administration of exogenous glucagon results in a pronounced hypolipemic response in man, dog, fowl ...
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