Results 221 to 230 of about 864,255 (364)

RNA‐seq analysis of mitochondria‐related genes regulated by AMPK in the human trophoblast cell line BeWo

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using RNA‐seq and other bioinformatics analyses, three clusters of mitochondria related genes, including aldo‐keto reductase family 1 members B10 and B15 (AKR1B10, AKR1B15), alanyl‐tRNA synthetase 1 (AARS1), mitochondrial ribosomal protein S6 (MRPS6), mitochondrial calcium uniporter dominant negative subunit beta (MCUB) and dihydrolipoamide branched ...
Bin Wu   +6 more
wiley   +1 more source

Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes

open access: yesJournal of Lipid Research, 2004
Previous reports attributed cholesteryl ester transfer protein (CETP)-mediated HDL cholesteryl ester (CE) selective uptake to the CETP-mediated transfer of CE from HDL to newly secreted apolipoprotein B-containing lipoproteins, which are then ...
Gerard Vassiliou, Ruth McPherson
doaj  

Establishment and characterization of liver‐specific Apoa4‐Cre and Cyp2c11‐Cre rat models in juvenile and adult stages

open access: yesAnimal Models and Experimental Medicine, EarlyView.
ApoA4‐Cre rats and Cyp2c11‐Cre rats were produced using CRISPR/Cas9 tool. The Cre rats were crossed with Rosa26‐imCherry rats to obtain the Apoa4‐Cre/Rosa26‐imCherry and Cyp2c11‐Cre/Rosa26‐imCherry rats, which showed the specific expression of Cre recombinases in the liver.
Wei Dong   +6 more
wiley   +1 more source

Predictors and morphological properties of culprit healed plaques in patients with angina pectoris

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1199-1210, December 2022., 2022
Abstract Background Plaque healing may serve a vital function in the natural progression of atherosclerotic disease. This study sought to investigate predictors and morphological characteristics of healed plaque (HP) among angina pectoris (AP) patients.
Hongying Yao   +5 more
wiley   +1 more source

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

open access: yesAnnals of Neurology, EarlyView.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund   +6 more
wiley   +1 more source

Survival benefit of overweight patients undergoing MitraClip® procedure in comparison to normal‐weight patients

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1236-1245, December 2022., 2022
Long‐term survival stratified for weight classes illustrated by Hazard plot for patients treated with MitraClip® implantation stratified for weight classes. Association of weight class compared to normal‐weight with long‐term survival (adjusted for Logistic EuroScore).
Karsten Keller   +12 more
wiley   +1 more source

Plasma lipoproteins in the golden Syrian hamster (Mesocricetus auratus): heterogeneity of apoB- and apoA-I-containing particles

open access: yesJournal of Lipid Research, 1993
We present the quantitative and qualitative characteristics of the apolipoprotein (apo) B- and apoA-I-containing lipoprotein subspecies in the plasma of male Golden Syrian hamsters.
S Goulinet, MJ Chapman
doaj  

Identification of the Micro‐Ribonucleic Acid Profiles of Plant‐Derived Extracellular Vesicles and their Potential Crosskingdom Regulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
The present study employs small RNA sequencing to identify the types and content of microRNAs (miRNAs) in four widely utilized plant‐derived extracellular vesicles (pEVs). The functional annotation reveals that the pEV miRNAs are involved in regulating the progression of human cancer and viral infection, thereby demonstrating the crosskingdom ...
Fei Wang   +7 more
wiley   +1 more source

Adherence with cardiovascular medications and the outcomes in patients with coronary arterial disease: “Real‐world” evidence

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1220-1228, December 2022., 2022
Abstract Background Cardiovascular medications are vital for the secondary prevention of coronary arterial disease (CAD). However, the effect of cardiovascular medication may depend on the optimal adherence of the patients. This meta‐analysis aims to determine the magnitude of adherence to vascular medications that influences the absolute and relative ...
Chen Chen   +5 more
wiley   +1 more source

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