Results 121 to 130 of about 428,553 (167)

Correction: Impact of Aspirin on Primary Prevention of Cardiovascular Events in Patients with Elevated Lipoprotein(a): A Systematic Review and Meta-analysis. [PDF]

Am J Cardiovasc Drugs
Caldeira D, Alves M, Avó-Baião R, Lopes A, Prada L, Pinto FJ.   +5 more
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Prognostic value of preoperative inflammatory cell-to-HDL cholesterol ratios in patients with non-metastatic clear cell renal cell carcinoma. [PDF]

Front Oncol
Qin M, Feng Z, Zhang C, Song W, Wang K, Chen Z.   +5 more
europepmc   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Associations between early improvements in atherogenic lipids and reported dietary changes after RYGB: a pilot exploratory analysis in women with type 2 diabetes. [PDF]

Clinics (Sao Paulo)
Lemos GO, Prudêncio APA, Santos RHN, Neto JV, Marcadenti A, Fisberg RM, Menezes H, Heymsfield SB, Torrinhas RS, Waitzberg DL.   +9 more
europepmc   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Monogenic Familial Chylomicronemia Syndrome in Children: Clinical Divergences and Management Paradigms. [PDF]

Cureus
Chan SYC, Yau HC, Chan KY, Fu A.
europepmc   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Evaluation of the first trimester maternal glycolipid profile on gestational diabetes mellitus: a case-control study in the hospital of rural Shanghai. [PDF]

BMJ Open
Li H, Zhang H, Ding L, Zhu J, Mi G, Li P, Wu J, Shen Y, Wu S, Jiang L.   +9 more
europepmc   +1 more source