Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
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Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley +22 more
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Lipoprotein(a): A New Intensive Care Unit Admission Predictor in Coronavirus Disease 2019 Patients [PDF]
OBJECTIVE: Endothelium-related events in patients with coronavirus disease 2019 are linked to a poor prognosis. Lipoprotein(a) plays a role in vascular endothelial cell dysfunction.
Alkan, Sevil +12 more
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HIV infection significantly reduces lipoprotein lipase which remains low after 6 months of antiretroviral therapy [PDF]
Purpose of the study Fractional clearance rate of apolipoprotein B100-containing lipoproteins is reduced in HIV infection before and after antiretroviral (ARV) treatment [1].
LL Gathercole +26 more
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Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects [PDF]
Background -Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower high-density lipoprotein (HDL) cholesterol, raise low-density lipoprotein (LDL ...
Wanders Anne J. +16 more
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Uptake of synthetic low density lipoprotein by leukemic stem cells — a potential stem cell targeted drug delivery strategy [PDF]
Chronic Myeloid Leukemia (CML) stem/progenitor cells, which over-express Bcr-Abl, respond to imatinib by a reversible block in proliferation without significant apoptosis.
Jørgensen, Heather G. +25 more
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Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
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Italian Multicenter Study on Low-Density Lipoprotein Apheresis Working Group 2009 Survey
We present results of the second survey of the Italian Multicenter Study on Low-Density Lipoprotein Apheresis (IMSLDLa-WG/2). The study involved 18 centers in 2009, treating 66 males and 35 females, mean age 47 +/- 18 years.
MOROZZI, CLAUDIA +3 more
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Effects of dalcetrapib in patients with a recent acute coronary syndrome [PDF]
In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events.
Chaitman Bernard R. +107 more
core +1 more source
OBJECTIVE: The association between cholesterol and endothelial dysfunction remains controversial. We tested the hypothesis that lipoprotein subclasses are associated with coronary endothelial dysfunction.
Prasad, A +8 more
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