Results 11 to 20 of about 440,409 (317)
Lipoproteins and Atherosclerosis [PDF]
Journal of Gerontology, 1951 Author(s): Gofman, John W.; Lindgren, Frank T.; Jones, Hardin B.; Lyon, Thomas P.; Strisower, Beverly.
John W. Gofman +4 more
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MMW - Fortschritte der Medizin, 2021 AbstractLipoprotein(a) [Lp(a)] is an atherogenic lipoprotein with a strong genetic regulation. Up to 90% of the concentrations are explained by a single gene, theLPAgene. The concentrations show a several-hundred-fold interindividual variability ranging from less than 0.1 mg/dL to more than 300 mg/dL. Lp(a) plasma concentrations above 30 mg/dL and even
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Lipoprotein (a): Recent Updates on a Unique Lipoprotein [PDF]
Current Atherosclerosis Reports, 2021 Genetic, epidemiological, and translational data indicate that Lipoprotein (a) [Lp(a)] is likely in the causal pathway for atherosclerotic cardiovascular diseases as well as calcification of the aortic valves.Lp(a) is structurally similar to low-density lipoprotein, but in addition to apolipoprotein B-100, it has a glycoprotein apolipoprotein(a) [apo(a)
Salim S. Virani +4 more
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Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis
Biomedicines, 2021 Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee +5 more
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JACC: Basic to Translational Science, 2020 [Figure: see text]
Michael D. Shapiro, Sergio Fazio
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Frontiers in Medicine, 2023 BackgroundPreeclampsia is a common and serious pregnancy-induced disease, with potential severe maternal and fetal complications. Recently, an increased lipoprotein (a) (Lp[a]) concentration, an important factor in cardiovascular diseases (CVDs ...
Joanna Marlȩga-Linert +5 more
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Lipoprotein apheresis to treat elevated lipoprotein (a) [PDF]
Journal of Lipid Research, 2016 An elevated plasma concentration of lipoprotein (a) [Lp(a)] is an independent risk factor for cardiovascular disease. Life style modification and currently available drugs either fail to effectively lower plasma Lp(a) levels or do not result in clinical benefit. However, lipoprotein apheresis is very efficient in decreasing Lp(a) concentrations.
Elisa Waldmann, Klaus G. Parhofer
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Accurate measurement of the cholesterol within lipoprotein(a) (Lp[a]‐C) and its contribution to low‐density lipoprotein cholesterol (LDL‐C) has important implications for risk assessment, diagnosis, and treatment of atherosclerotic ...
Weili Zheng +13 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background Conventional "low‐density lipoprotein cholesterol (LDL‐C)" assays measure cholesterol content in both low‐density lipoprotein and lipoprotein(a) particles.
Peter Willeit +6 more
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Lipoprotein (a) and stroke [PDF]
Journal of Clinical Pathology, 2000 Strokes are one of the most common causes of mortality and long term severe disability. There is evidence that lipoprotein (a) (Lp(a)) is a predictor of many forms of vascular disease, including premature coronary artery disease. Several studies have also evaluated the association between Lp(a) and ischaemic (thrombotic) stroke. Several cross sectional
Milionis, H. J. +2 more
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