Lipoprotein metabolism and its impact on life expectancy
Experimental GerontologyPurpose: The aim of this review is to explore the relationship between lipoprotein metabolism and life expectancy across species. The central research question addresses how different classes of lipoproteins (chylomicrons, VLDL, LDL, HDL) and their ...
Michał Skrzycki, Wojciech Graboń
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Polymorphisms of lipoprotein lipase gene and their participation in metabolic processes Polimorfizmy genu lipazy lipoproteinowej i ich udział w procesach metabolicznych [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2011 Lipoprotein lipase (LPL) plays a central role in dyslipidemia and development of metabolic syndrome. The occurrence of polymorphisms of the LPL gene may result in the disturbance in the lipid metabolism and pathogenesis of CAD.
Ewa Barg, 0 0
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In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases
Advanced Science, EarlyView.This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du +6 more
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Triglyceride and high density lipoprotein metabolism in diabetes [PDF]
, 2018 G. H. Tomkin
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Advanced Science, EarlyView.To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun +6 more
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Lipoprotein metabolism in Alzheimer’s disease: CSF and plasma HDL characterization in an Italian cohort [PDF]
, 2022 M. Turri +7 more
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Advanced Science, EarlyView.Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu +10 more
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Trakia Journal of SciencesPURPOSE: The aim of the study was to evaluate the effects of chronic poloxamer 407 treatment on some parameters of lipid and glucose metabolism in a rat experimental model and to test the potential of this treatment to induce a condition similar ...
P. Dzhelebov, K. Trifonova
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A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk
Advanced Science, EarlyView.A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan +12 more
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Dietary polyunsaturated fat intake is associated with low-density lipoprotein size, but not with susceptibility to oxidation in subjects with impaired glucose metabolism and type II diabetes: the Hoorn study [PDF]
, 2006 G.A.M. van den Bos +9 more
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