Results 81 to 90 of about 115,025,331 (252)
CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features
Advanced Science, EarlyView.CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang +19 morewiley +1 more sourceANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function
Advanced Science, EarlyView.In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li +7 morewiley +1 more sourcePlasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration[S]
Journal of Lipid Research, 2017 Disturbance in lipid metabolism has been suggested as a major pathogenic factor for age-related macular degeneration (AMD). Conventional lipid measures have been inconsistently associated with AMD.Chui Ming Gemmy Cheung, Alfred Gan, Qiao Fan, Miao Ling Chee, Rajendra S. Apte, Chiea Chuen Khor, Ian Yeo, Ranjana Mathur, Ching-Yu Cheng, Tien Yin Wong, E. Shyong Tai +10 moredoaj +1 more sourceBiological, clinical and population relevance of 95 loci for blood lipids [PDF]
, 2010 Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic ...J. Sinisalo, Döring, Angela, Boehnke, M., N. G. Martin, Silander, K, Ridker, P.M., P. Elliott, Lamina, C., Assimes, Themistocles L., L. L. Bonnycastle, Ingelsson, E., Kastelein, JJP, Ingelsson, E,, N. J. Wareham, Teslovich, T.M., Ejebe, K.G., Sanna, Serena, Hall, A.S. (Alistair), McCarthy, Mark I, Boerwinkle, E., Teslovich, Tanya M., Parker, A.N., Surakka, I., L. M. Rose, Hicks, Andrew A, Boekholdt, S Matthijs, James P. Pirruccello, Hengstenberg, Christian, Mangino, M., Ruokonen, A., Bandinelli, S, Toshiko Tanaka, Shin Cho, Y. (Yoon), Kim, Young Jin, A. S. Hall, Bonnycastle, LL, Sanna, S., Peloso, Gina M, Elena Gonzalez, Silander, K., Rose, LM, Uitterlinden, Andre G., Smith, AV, C. Hengstenberg, Shin Cho, Y., Kaprio, Jaakko, T. Y. Wong, Edmondson, Andrew C., Jin Kim, Y. (Young), Pare, G. (Guillaume), Go, MJ, Y. d. I, Kastelein, J.J.P. (John), Hastie, Nicholas D, Orho-Melander, M. (Marju), Rick Twee-Hee Ong, Johansen, C.T. (Christopher), Loos, Ruth J F, Kronenberg, F. (Florian), T. Tanaka, S. Kathiresan, Kim, K., Stefansson, K, Whitfield, JB, Willemsen, G.A.H.M. (Gonneke), Tai, E.S., O'Donnell, CJ, Johansson, Asa, Wichmann, H.E. (Heinz Erich), Altshuler, D., Shin Cho, Yoon, Seielstad, M, Kronenberg, Florian, Johansen, C.T., Zee, RYL, Montgomery, G.W., Rose, Lynda M, Hofman, A., Roberts, Robert, Igl, W., Harris, T.B. (Tamara), Haritunians, T. (Talin), Smith, Albert V, Jin Kim, Y, Launer, Lenore J, Ziegler, A, Quertermous, T., Waterworth, D. (Dawn), Seielstad, Mark, Smit, J.H., Jarvelin, Marjo-Riitta, Li, Mingyao, Munroe, PB, de Geus, E.J., Cupples, L.A. (Adrienne), C. T. Johansen, Voight, Benjamin F., J. S. Kooner, Mary F. Feitosa, Sijbrands, E.J.G.; id_orcid, Rose, L.M. (Lynda), de Geus, Eco J C, Kastelein, John JP, König, I.R. (Inke), Kirsten O. Kyvik, Gabriel, S.B., Bergman, R.N., Stacey B. Gabriel, Gonzalez, E, Gyllensten, Ulf,, Strachan, David P., Hall, AS, Salomaa, Veikko, Wilson, James G.; id_orcid, Bergman, Richard N., M. J. Caulfield, Markku S. Nieminen, Collins, Francis S, Tai, E.-Shyong, Wendy McArdle, Groop, L.C., Johnson, T, Ong, RTH, Ingelsson, Erik, Penninx, B.W.J.H., Rudan, I. (Igor), Freimer, N.B. (Nelson), X. Sim, Lori L. Bonnycastle, Edmondson, A.C., G. M. Peloso, Guillaume Lettre, O’Donnell, Christopher J., Uitterlinden, Andre G, Kiran Musunuru, K. Kim, de Geus, EJ, Smith, A.V. (Albert Vernon), D. C. Croteau Chonka, McCarthy, MI, Benjamin F. Voight, Kuzawa, Christopher W, Gyllensten, U., Pramstaller, P.P. (Peter Paul), Janssens, A.C., Zhang, W., Schlessinger, D. (David), Stylianou, IM, Burtt, Noel P., M. Li, Reilly, Muredach P., Vitart, Veronique, Crawford, G., Kaplan, L.M., Ruokonen, A. (Aimo), Johansson, Åsa,, Waterworth, Dawn M., Taylor Jr, Herman A., Park, Taesung, Stringham, Heather M., Martin, Nicholas G, Launer, L.J., Scuteri, Angelo, A. Johansson, Cupples, L.A., Lucas, Gavin, Edmondson, A.C. (Andrew), C. Langenberg, Lettre, G, Yurii S. Aulchenko, Chasman, Daniel I., A. B. Feranil, Christian Hengstenberg, Wright, A.F., Caulfield, M.J., Dominiczak, Anna F, Hastie, Nicholas D., Kooner, J.S., Magnusson, Patrik KE, Schunkert, H, Cho, YS, Jaakko Tuomilehto, Gieger, C. (Christian), Hegele, Robert A, Thompson, JR, U. Gyllensten, James G. Wilson, Sinisalo, J., Nickerson, D.A., Sijbrands, Eric JG, Sijbrands, EJG, Igi, Wilmar, Nicholas G. Martin, Wareham, N.J., Sabatti, Chiara, A. F. Wright, Christie M. Ballantyne, Mangino, M, Ulf Gyllensten, de Faire, Ulf, Kooner, Jaspal S, Li, XH, Peter P. Pramstaller, Saharinen, J, Sandhu, M.S. (Manjinder), M. S. Sandhu, Yuan, X., Erdmann, Jeanette, I. M. Heid, Nicholas J. Wareham, R. T. Ong, B. A. Oostra, Loos, Ruth J. F., Stringham, H.M. (Heather), Pare, G, Rader, D.J. (Daniel), Pedersen, Nancy L., Peloso, G.M. (Gina), Johannes H. Smit, Ida Surakka, Schadt, E.E., Duijn, C.M. van, Pedersen, Nancy L, M. Mangino, Loos, RJF, Hicks, Andrew A., Munroe, Patricia B., Havulinna, A.S. (Aki), Collins, F.S., Whitfield, J. (John), Scott, J, A. V. Smith, H. A. Taylor, Wilson, James F, Wilson, James G, L. Ferrucci, J. M. Ordovas, O'Donnell, C.J. (Christopher), Quertermous, Thomas, M. F. Feitosa, Gyllensten, Ulf, D. P. Strachan, Parker, AN, Ballantyne, C.M., Stringham, He.M., Ripatti, S., S. Bandinelli, Pedersen, N.L. (Nancy), Perola, Markus, Cristian Pattaro, Holm, Hilma, de Faire, U., Waterworth, DM, de Geus, EJC, Ruokonen, Aimo, Hottenga, JJ (Jouke Jan), Groop, Leif C, Erdmann, J, Alex N. Parker, Wright, AF, Aulchenko, Y.S., Hottenga, J.J., Musunuru, K., Lange, Leslie A., L. A. Lange, Toby Johnson, Twee-Hee Ong, R., Iris M. Heid, Kooner, J.S. (Jaspal), Cornelia M. van Duijn, Hicks, A.A., Musunuru, K, Smit, Johannes H, Sijbrands, EJ, Marroni, F. (Fabio), Feitosa, Mary F, Nancy L. Pedersen, Hua Zhao, Jing, Kim, Kyunga, Tai, E.-S., Bergman, RN, Waterworth, Dawn M, Hovingh, G Kees, Melander, O, Thorsteinsdottir, U, R. A. Hegele, Wilson, James; id_orcid, Jarvelin, MR, Ziegler, Andreas, A. Scuteri, Wright, A.F. (Alan), Jin Go, Min, Jing Hua Zhao, Igi, Wilmar,, Salomaa, V. (Veikko), van Duijn, Cornelia M., Hegele, R.A. (Robert), McArdle, W.L. (Wendy), Melander, O. (Olle), B. F. Voight, Vitart, V. (Veronique), Thorsteinsdottir, U. (Unnur), Luan, J., Rotter, J.I., Jarvelin, M.-R., Groop, L. (Leif), Lakatta, Edward G., Psaty, B.M. (Bruce), Gavin Lucas, Orho-Melander, Marju,, G. Kees Hovingh, Rudan, I., Groop, LC, A. S. Havulinna, Ejebe, KG, R. Laaksonen, U. d. Faire, Barroso, Ines, R. Roberts, Gabriel, Stacey B., Tim D. Spector, Collins, FS, Wilson, James F., Kathiresan, S. (Sekar), Kastelein, John J. P., Ruokonen, A, Wilson, James G., Stylianou, I.M., Gonzalez, E., Jin Kim, Young, Zhao, JH, Alan R. Tall, Oostra, Ben A, Kees Hovingh, G, Schlessinger, David, Pramstaller, PP, Lange, Leslie A, Döring, A. (Angela), Ingelsson, E, Vollenweider, P, J. C. M, Igl, W, Wilmar Igl, Janssens, A Cecile JW, Orho-Melander, M, Jaspal S. Kooner, Yuan, Xin, Ordovas, JM, Thomas Meitinger, Sijbrands, Eric J. G., Lamina, Claudia, Barroso, I.E. (Inês), Elliott, P., Li, X., N. L. Pedersen, Dawn M. Waterworth, R. J. F, Kuzawa, CW, Gonzalez, E. (Elena), L. A. Cupples, Kuzawa, Christopher W., N. D. Hastie, Claudia Lamina, Robert Y. L. Zee, Demissie, Serkalem, Luan, JA, McCarthy, M.I. (Mark), P. K. E, Altshuler, David, Aimo Ruokonen, Tanaka, T, Kim, YJ, Marjo-Riitta Jarvelin, Aulchenko, Y.S. (Yurii), C. Gieger, Francis S. Collins, Luan, Jian'an, M. S. Nieminen, Psaty, Bruce M., Stringham, Heather M, K. G. Ejebe, Kyunga Kim, Hegele, RA, Joshua D. Smith, Caulfield, Mark J., Tuomilehto, J., J. F. Wilson, Feitosa, MF, Gyllensten, U, U. Thorsteinsdottir, Taylor, Herman A, Munroe, Patricia B, John Chambers, D. J. Rader, L. Adrienne Cupples, I. R. König, Sandhu, Manjinder S., Robert Roberts, K. Musunuru, Deloukas, P, Guiducci, Candace, Laaksonen, R. (Reijo), J. I. Rotter, Ejebe, K.G. (Kenechi), G. R. Abecasis, Andrew A. Hicks, Luben, R.N. (Robert), Ordovas, J.M. (Jose), Bis, Joshua C, Andre G. Uitterlinden, Pirruccello, J.P., Crawford, G. (Gabe), Song, K. (Kijoung), D. Masson, Serena Sanna, Stylianou, Ioannis M, Doering, A, Lokki, ML, Lakatta, EG, Heid, I.M. (Iris), Salomaa, V., Bis, J.C. (Joshua), Smith, Joshua D, Uda, M, Magnusson, Patrik K. E., Chasman, D.I. (Daniel), Ejebe, Kenechi G., E. Ingelsson, Mohlke, K.L., Hall, Alistair S., Guiducci, C, Campbell, Harry, Panagiotis Deloukas, Barbalic, M., Song, K, Laaksonen, Reijo, Fouchier, S.W., Vollenweider, P., Lettre, G., Waeber, G. (Gérard), de Geus, Eco JC, Linda S. Adair, Chambers, John, Y. S. Aulchenko, P. P. Pramstaller, Voight, Benjamin F, Scott, J., Collins, F.S. (Francis), Guo, X., Xin Yuan, C. M. van, Leena Peltonen, Magnusson, Patrik K E, Feitosa, M.F. (Mary Furlan), Rotter, J.I. (Jerome), Zee, Robert YL, L. S. Adair, Meitinger, T., Jacqueline C. M. Witteman, Penninx, BW, Jeanette Erdmann, Kari Stefansson, Kaprio, J., Åsa Johansson, Masson, D., Scott, J. (James), Lange, LA, Khaw, KT, Hottenga, J.J. (Jouke Jan), Albert V. Smith, Smith, A.V., Paul M Ridker, Gonçalo R. Abecasis, Mohlke, K.L. (Karen), Ripatti, S, Groop, Leif C., Hengstenberg, C, David P. Strachan, Burtt, N.P., Wilson, J.G., Erdmann, J. (Jeanette), Wareham, Nicholas J, Chasman, DI, Döring, A., Alan B. Feranil, Barroso, I., Boekholdt, S. Matthijs, Xiaohui Li, Nicholas D. Hastie, Vilmundur Gudnason, Doering, Angela, Cristen J. Willer, Thompson, J.R., Schadt, E.E. (Eric), Heid, Iris M, Li, M., Hegele, R.A., Pedersen, N.L., Bis, J.C., Wilson, J.F., Yii-der I. Chen, Guiducci, C. (Candace), D. Schlessinger, Samani, N.J., Kaplan, LM, G. Thorleifsson, Kathiresan, S, Rader, Daniel J., Jarvelin, M.-R. (Marjo-Riitta), Herman A. Taylor Jr, Pedersen, NL, T. Johnson, J. Hottenga, Saharinen, J. (Juha), Penninx, Brenda W. J. H., Willer, C.J. (Cristen), Li, MY, Wong, Tien Y, Soranzo, N., Peltonen, Leena, Dominiczak, A.F., Adair, LS, Waeber, G., Li, M, Boehnke, Michael, Rieder, M. (Mark), Perola, M. (Markus), Lenore J. Launer, Campbell, H., Wichmann, HE, Scott, James, Freimer, N.B., Isaacs, A., Heather M. Stringham, Luben, R, Pirruccello, JP, Pichler, Irene, Mark I. McCarthy, Alistair S. Hall, Silander, Kaisa, Y. J. Kim, Smit, Johannes H., Masson, D. (David), Boerwinkle, E.A. (Eric), Thompson, J.R. (John), Hovingh, G. Kees, Kaprio, J, Marroni, F, Pattaro, C., Bis, Joshua C., Kaprio, J. (Jaakko), Tanaka, T. (Toshiko), Peloso, G.M., Candace Guiducci, Tall, A.R. (Alan), Feranil, Al.B., Dominiczak, Anna F., Magnusson, P.K. (Patrik), Pattaro, Cristian, C. Hayward, Li, X, Young Jin Kim, J. Erdmann, Pattaro, C, C. Guiducci, Guo, X. (Xiuqing), David Schlessinger, Abecasis, Gonçalo R, Bandinelli, S. (Stefania), Hottenga, JJ, Cupples, L Adrienne, Hilma Holm, Saharinen, Juha, Aulchenko, Yurii S., Cupples, L. Adrienne, Kastelein, J.J.P., Pirruccello, J.P. (James), E. J. C, Veikko Salomaa, Lakatta, Edward G, de Geus, E.J.C., H. M. Stringham, J. Scott, Dorret I. Boomsma, Willemsen, G.; id_orcid, Khaw, Kay-Tee, Montgomery, Grant W, Sijbrands, E.J.G. (Eric), Zee, Robert Y L, J. J. P, Holm, H, Kastelein, John J.P., Roberts, R., Teslovich, TM, Stefansson, Kari, Peltonen, L. (Leena Johanna), M. Seielstad, Sekar Kathiresan, Samani, Nilesh J, V. Mooser, Rose, L.M., Spector, T.D. (Timothy), Kaisa Silander, Smith, Joshua D., Boomsma, Dorret I., Lange, L.A. (Leslie), Melander, O., Vollenweider, Peter, A. G. Uitterlinden, I. Surakka, Wong, T.Y., G. K. Hovingh, Soranzo, Nicole, A. C. J, Hayward, Caroline, Hofman, A. (Albert), Zhao, J.H. (Jing Hua), Albert Hofman, H. Wichmann, Voight, B.F., Elliott, P, Voight, B.F. (Benjamin), Igl, Wilmar, Ordovas, Jose M, B. W. J, Kaplan, Lee M, Willer, Cristen J, Gieger, Christian, König, Inke R., Geus, E.J.C. (Eco) de, Patrik K. E. Magnusson, Tanya M. Teslovich, Sim, X., Johansson, Å., Caulfield, MJ, Dominiczak, AF, Stylianou, Ioannis M., Brenda W. J. H. Penninx, Bonnycastle, L.L., Gabriel Crawford, Haritunians, T., I. Barroso, Gabriel, S.B. (Stacey), Loos, RJ, Kooner, Jaspal S., Jin Go, M. (Min), C. M. Ballantyne, Kooner, JS, Lamina, C, Hicks, AA, Roberts, R. (Robert), Krauss, Ronald M, Thorleifsson, Gudmar, J. B. Whitfield, H. Schunkert, Pirruccello, James P., Orho-Melander, M., Lakatta, E.G., Janssens, A. Cecile J. W., Oostra, B.A., Luan, J, Christian Gieger, Krauss, R.M. (Ronald), Cecile, A. (A.), S. B. Gabriel, Heribert Schunkert, Magnusson, P.K.E., Nickerson, Deborah A, Aki S. Havulinna, Bergman, Richard N, Hayward, C. (Caroline), Oostra, Ben, Chen, YD, Ingrid B. Borecki, P. B. Munroe, Lynda M. Rose, Daniel J. Rader, Song, Kijoung, Michael Boehnke, Hottenga, Jouke-Jan, Schunkert, Heribert, Spector, T.D., Sijbrands, E.J., Loos, R.J.F., Hall, Alistair S, Lange, L.A., Isaacs, Aaron, Christopher W. Kuzawa, G. W. Montgomery, Haritunians, T, Wilson, JG, Kathiresan, Sekar, Wilson, JF, Waeber, G, Masahiro Koseki, D. Altshuler, Tai, E-Shyong, Aulchenko, Yurii S, D. A. Nickerson, Markus Perola, Loos, R.J., G. Willemsen, Perola, M., Inke R. König, Penninx, B.W.J.H. (Brenda), Zee, R.Y., de Geus, Eco J. C., Ballantyne, CM, Holm, H., Lamina, C. (Claudia), X. Li, Sanna, S. (Serena), Tien Y. Wong, I. B. Borecki, Chasman, D.I., J. Saharinen, A. Ruokonen, Karen L. Mohlke, Sandhu, M.S., Musunuru, Kiran, Borecki, I.B., Adair, Linda S, Johnson, T. (Toby), Wilson, J.F. (James), Fouchier, Sigrid W, Wong, TY, Meitinger, T. (Thomas), Dominiczak, A. (Anna), Kenechi G. Ejebe, Ripatti, Samuli, McPherson, R., Deloukas, P. (Panagiotis), E. J. G, Y. S. Cho, Masson, David, Lucas, G., Langenberg, C. (Claudia), Chen, Yii-der I., Lee, JY, Tuomilehto, Jaakko, Ridker, Paul M., A. Isaacs, Ioannis M. Stylianou, Ricketts, S.L., Kronenberg, F, Ulf de Faire, Uda, M., Laaksonen, R, Samani, NJ, Freimer, Nelson B, Witteman, JC, Ballantyne, C. (Christie), Wong, Tien Y., V. Gudnason, Demissie, S, Harris, Tamara B, M. Koseki, X. Guo, Kathiresan, S., Mark Rieder, Montgomery, G.W. (Grant), Kijoung Song, Hegele, Robert A., Jin Kim, Y., D. M. Waterworth, Kyvik, KO, Campbell, H. (Harry), Taylor Jr., H.A., Caulfield, M. (Mark), L. J. Launer, Sandhu, MS, Boehnke, M, Ruth J. F. Loos, Sanna, S, H.-Erich Wichmann, Wichmann, H.-E., Elliott, Paul, Hua Zhao, J., Freimer, NB, Johansen, Christopher T., J. Lee, Peltonen, L, M. Lokki, Wright, Alan, Borecki, IB, König, Inke R, Hottenga, J.-J., Langenberg, C, Yuan, X. (Xin), Taylor, Herman A., Jr., Melander, Olle,, Borecki, Ingrid B., Peter Vollenweider, Ziegler, A., Assimes, T.L. (Themistocles), T. M. Teslovich, Yoon Shin Cho, Ben A. Oostra, J. D. Smith, E. E. Schadt, Manuela Uda, Serkalem Demissie, Stylianou, I.M. (Ioannis), Thorleifsson, G. (Gudmar), Gonzalez, Elena, Boerwinkle, Eric, Schadt, EE, Ejebe, Kenechi G, Parker, A.N. (Alex), Koseki, M. (Masahiro), Christopher T. Johansen, Wichmann, H.E., Zee, R.Y.L., Heid, I.M., Zhang, W, Boerwinkle, E, Mooser, Vincent, Uitterlinden, AG, Bis, JC, Lettre, Guillaume, Bandinelli, S., Krauss, Ronald M., Nickerson, D.A. (Deborah), Taylor, HA, Manjinder S. Sandhu, Gieger, C, Gabriel, Stacey B, Kuzawa, C.W., Tai, ES, Laaksonen, R., Min Jin Go, Gérard Waeber, Tamara B. Harris, Cecile J. W. Janssens, A., Khaw, K-T. (Kay-Tee), Surakka, Ida, Wichmann, H-Erich, M. Barbalic, Twee-Hee Ong, Rick, Xueling Sim, Unnur Thorsteinsdottir, Nelson B. Freimer, Croteau-Chonka, Damien C, Wright, Alan F, Schlessinger, D., Twee-Hee Ong, R. (Rick), Robert Luben, Guillaume Pare, Silander, K. (Kaisa), Damien C. Croteau-Chonka, H. Campbell, Mark J. Caulfield, Croteau-Chonka, DC, van Duijn, CM, Lee, J.Y., Jerome I. Rotter, Fouchier, Sigrid W., Schadt, Eric E., Kyvik, Kirsten O; id_orcid, F. S. Collins, K. L. Mohlke, Havulinna, Aki S., Marju Orho-Melander, Campbell, Harry; id_orcid, I. Rudan, Freimer, Nelson B., Jarvelin, M.R., Ferrucci, L. (Luigi), Chasman, Daniel I, A. Cecile J. W. Janssens, Havulinna, A.S., Nieminen, MS, Martin, NG, A. F. Dominiczak, Pirruccello, James P, Johnson, T., Munroe, P. (Patricia), Salomaa, V, Zhao, Jing Hua, Sabatti, C. (Chiara), Jose M. Ordovas, Florian Kronenberg, C. Lamina, Perola, M, Zwart, J-A. (John-Anker), Duijn, Cornelia, Marroni, Fabio, Witteman, Jacqueline C M, Kaplan, Lee M., Ronald M. Krauss, Borecki, Ingrid B, Croteau-Chonka, D.C., Rieder, M., Altshuler, D. (David), Ordovas, J.M., Soranzo, N. (Nicole), Eco J. C. de Geus, Kaplan, R.C. (Robert), Magnusson, PK, S. W. Fouchier, Mark Seielstad, Uda, Manuela, Guo, Xiuqing, Bandinelli, Stefania, X. Yuan, Krauss, RM, Parker, Alex N., K. Khaw, Sigrid W. Fouchier, Jian’an Luan, Pichler, I, Teslovich, Tanya M, A. N. Parker, Launer, Lenore J., Chambers, J. (John), Daniel I. Chasman, Loos, R.J.F. (Ruth), Ballantyne, Christie M, Kronenberg, F., Wareham, N.J. (Nick), Adair, L.S., Nieminen, Markku S, Igi, W, Marja-Liisa Lokki, Koenig, Inke R., M. J. Go, Scuteri, A., Gudnason, V. (Vilmundur), Abecasis, G.R., Luan, Jian’an, Boekholdt, S.M., Hengstenberg, C. (Christian), Schunkert, H., W. Igl, Reilly, M.P. (Muredach), Rotter, Jerome I, Tuomilehto, J. (Jaakko), Alan F. Wright, Claudia Langenberg, Thompson, John R, Whitfield, John B, Penninx, BWJH, McPherson, R. (Ruth), Stringham, H.M., Andreas Ziegler, Fouchier, SW, Vincent Mooser, Thompson, John R., Janssens, Cecile, N. J. Samani, J. H. Zhao, Lokki, Marja-Liisa, Lee, J.-Y., Themistocles L. Assimes, Erdmann, J., Ferrucci, L, Rader, Daniel J, Kyvik, K.O. (Kirsten Ohm), van Duijn, C.M., A. A. Hicks, Parker, Alex N, J. Chambers, Uitterlinden, A.G. (André), Penninx, Brenda WJH, Peloso, Gina M., S. M. Boekholdt, Lund University., Peloso, GM, Lee, J.Y. (Jong Young), Ridker, PM, R. Luben, Lucas, G. (Gavin), Luigi Ferrucci, N. Soranzo, McPherson, R, Paul Elliott, Kaplan, L. M., Reilly, MP, John B. Whitfield, Willer, C.J., G. Waeber, Gudnason, V, Deloukas, P., J. G. Wilson, Yuan, X, E. G. Lakatta, Mooser, V. (Vincent), Jin Go, M., Isaacs, A.J. (Aaron), Li, Xiaohui, Ordovas, Jose M., Muredach P. Reilly, J. P. Pirruccello, Zee, Robert Y. L., Haritunians, Talin, Robert A. Hegele, Edmondson, AC, Cupples, LA, A. C. Edmondson, James Scott +999 morecore +1 more sourceCopper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy
Advanced Science, EarlyView.CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li +14 morewiley +1 more sourceNew mouse models for lipoprotein metabolism and atherosclerosis
, 2002 Cardiovascular Research Institute Maastricht, Department of Molecular Genetics, University of Maastricht, Maastricht, The Netherlands. Transgenic mouse models have been crucial to our current understanding of the mechanisms of lipoprotein metabolism ...Hofker, M.H., de Winther, Menno P. J., Hofker, Marten H., de Winther, M.P.J. +3 morecore +1 more sourceA Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair
Advanced Science, EarlyView.A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan +17 morewiley +1 more source
