Results 61 to 70 of about 219,582 (315)

Differential effects of interferon-γ on metabolism of lipoprotein immune complexes mediated by specific human macrophage Fcγ receptors

Journal of Lipid Research, 2000
: The objectives were to determine whether there are differences in the mechanisms of lipoprotein metabolism associated with different FcγRs and how metabolism associated with FcγRs compares to that mediated by scavenger receptors (SRA).
Peter M. Morganelli, Susan M. Kennedy, Teresa I. Mitchell   +2 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Apoprotein (a) isoforms: a link with quantitative levels of lipoprotein(a), aspects of multi-stage atherogenicity and other apo (a) correlations

Атеросклероз, 2012
Most of the recent studies demonstrate that the quantitative level of Lp(a) and especially its low-molecular apo(a) phenotypes are independent risk factors of coronary atherosclerosis and correlate directly with the appearance, progress, and severity of
A. V. Tikhonov, A. V. Shabalin, Yu. I. Ragino, Yu. P. Nikitin   +3 more
doaj  

Hepatic Lipoprotein Metabolism: Current and Future In Vitro Cell-Based Systems

Biomolecules
Changes in hepatic lipoprotein metabolism are responsible for the majority of metabolic dysfunction-associated disorders, including familial hypercholesterolemia (FH), metabolic syndrome (MetS), metabolic dysfunction-associated fatty liver disease (MAFLD)
Izabella Kiss, Nicole Neuwert, Raimund Oberle, Markus Hengstschläger, Selma Osmanagic-Myers, Herbert Stangl   +5 more
doaj   +1 more source

Hypertension as a disease of carbohydrate and lipoprotein metabolism

The American Journal of Medicine, 1989
Patients with untreated hypertension have been shown to be resistant to insulin-stimulated glucose uptake and both hyperinsulinemic and hypertriglyceridemic when compared with matched control groups with normal blood pressure. In addition, insulin resistance, hyperinsulinemia, and hypertriglyceridemia have been demonstrated in rat models of ...
G M, Reaven, B B, Hoffman
openaire   +2 more sources

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Lipoprotein(a) and atherosclerosis

Атеросклероз, 2007
Lp(a) lipoprotein is one of atherogenic forms of lipoproteins, it was discovered over 45 years ago. Lp(a) is a quantitative feature, its concentration being under polygenic control.
A. V. Tikhonov
doaj  

The effect of a low carbohydrate high fat diet on lipid and lipoprotein metabolism: insight from a RCT [PDF]

, 2023
Deaglan McCullough, T. Harrison, Lynne M. Boddy, Kevin Enright, F. Amirabdollahian, Mohsen Mazidi, Katie Lane, Claire E. Stewart, Ian G. Davies   +8 more
openalex   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Overfeeding increases very low density lipoprotein diameter and causes the appearance of a unique lipoprotein particle in association with failed yolk deposition.

Journal of Lipid Research, 1994
Structurally specific very low density lipoprotein (VLDL) particles are presumed to redirect VLDL uptake during yolk deposition. Egg production is an energy intensive process, but energy excess negatively affects egg production.
R L Walzem, P A Davis, R J Hansen
doaj   +1 more source