Results 51 to 60 of about 115,025,331 (252)

New insights into the role of glycosylation in lipoprotein metabolism

, 2017
Purpose of reviewHuman genetics has provided new insights into the role of protein glycosylation in regulating lipoprotein metabolism. Here we review these new developments and discuss the biological insights they provide.Recent findingsCase descriptions
Marjolein A.W. van den Boogert, Holleboom, Adriaan G., Daniel J. Rader, Adriaan G. Holleboom, van den Boogert, Marjolein A. W., Rader, Daniel J.   +5 more
core   +1 more source

Changes in the Plasma Lipid Profile as a Potential Predictor of Clinical Outcome in Dengue Hemorrhagic Fever [PDF]

, 2002
In 50 consecutive children admitted to the intensive care unit with the clinical diagnosis of dengue hemorrhagic fever (DHF)/dengue shock syndrome (grade III or IV), 20 patients with mild DHF (grade I or II), and 20 healthy control patients, the plasma ...
Suharti, C., Gorp, E. van, van der Meer, Jos W. M., Dolmans, Wil M. V., Meer, J.W.M. van der, Mairuhu, A.T., van der Ven-Jongekrijg, Johanna, Ven-Jongekrijg, J. van der, Demacker, P.N.M., Dolmans, W.M.V., Mairuhu, A.T.A., Mairuhu, ATA, Ven, J. van der, Suharti, Catharina, van Gorp, Eric C. M., Demacker, Pierre N M, Gorp, E.C.M. van   +16 more
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Zebrafish yolk lipid processing: a tractable tool for the study of vertebrate lipid transport and metabolism

Disease Models & Mechanisms, 2014
Dyslipidemias are a major cause of morbidity and mortality in the world, particularly in developed nations. Investigating lipid and lipoprotein metabolism in experimentally tractable animal models is a crucial step towards understanding and treating ...
Rosa L. Miyares, Vitor B. de Rezende, Steven A. Farber   +2 more
doaj   +1 more source

Lipoprotein metabolism model.

, 2014
A. Visualization of the HDL metabolism model. The central lipoprotein represents the lipoprotein with grid coordinates (i,j). The arrows represent the 6 processes that together determine the HDL distribution.
Fianne L. P. Sips (557973), Maaike H. Oosterveer (262779), Christian A. Tiemann (440657), Natal A. W. van Riel (175595), Albert K. Groen (128588), Peter A. J. Hilbers (175592)   +5 more
core   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Lipoprotein(a) and multi-stage atherogenesis: coronary atherosclerosis, cerebrovascular complications and other correlations of Lp(a) and apo(a)

Атеросклероз, 2010
A connection of the level of Lp(a) with the presence and extent of atherosclerosis of main arte ries of head was proved. It was demonstrated that this level in the patients who survived stroke is reliably higher than that in the patients from reference ...
A. V. Tikhonov, Yu. P. Nikitin
doaj  

Hepatic metabolism and secretion of a cholesterol-enriched lipoprotein fraction.

Journal of Lipid Research, 1987
A potentially important source of cholesterol secreted in bile is cholesterol-rich lipoproteins. However, the fate of the cholesterol carried in these lipoproteins after hepatic uptake has not been investigated. We harvested an apoE- and cholesterol-rich
B G Stone, D Schreiber, L D Alleman, C Y Ho   +3 more
doaj   +1 more source

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source