Plasma lipoproteins: apolipoprotein structure and function.
Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-II, apoA-IV, apoC-I, apoC-II, and apoC-III ...
R W Mahley+3 more
doaj
Lipoprotein(a) and atherosclerosis
Lp(a) lipoprotein is one of atherogenic forms of lipoproteins, it was discovered over 45 years ago. Lp(a) is a quantitative feature, its concentration being under polygenic control.
A. V. Tikhonov
doaj
Postprandial lipoprotein metabolism and atherosclerosis
The metabolism of chylomicrons and their remnants is a highly facilitated route to distribute energy from the diet for storage in adipose tissue or immediate use in the muscles. It has been proposed that chylomicron remnants are atherogenic, and a delayed clearance of chylomicron remnants seems to be associated with compositional abnormalities of other
Karpe, F, Hamsten, A
openaire +4 more sources
Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. [PDF]
Animals suffering from malignancy or chronic infection develop characteristic metabolic abnormalities, including a well-defined hypertriglyceridemic state.
Bradley, WA+6 more
core
Oxylipin transport by lipoprotein particles and its functional implications for cardiometabolic and neurological disorders [PDF]
Lipoprotein metabolism is critical to inflammation. While the periphery and central nervous system (CNS) have separate yet connected lipoprotein systems, impaired lipoprotein metabolism is implicated in both cardiometabolic and neurological disorders ...
Borkowska, Alison+7 more
core +1 more source
Most of the recent studies demonstrate that the quantitative level of Lp(a) and especially its low-molecular apo(a) phenotypes are independent risk factors of coronary atherosclerosis and correlate directly with the appearance, progress, and severity of
A. V. Tikhonov+3 more
doaj
Modelling the inflammatory process in atherosclerosis: a nonlinear renewal equation [PDF]
We present here a population structured model to describe the dynamics of macrophage cells. The model involves the interactions between modified LDL, monocytes/macrophages, cytokines and foam cells. The key assumption is that the individual macrophage dynamics depends on the amount of lipoproteins it has internalized.
arxiv
Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Fischer, S.+5 more
core +1 more source
ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36
The class B scavenger receptors SR-BI and CD36 exhibit a broad ligand binding specificity. SR-BI is well characterized as a HDL receptor that mediates selective cholesteryl ester uptake from HDL.
Maria C. de Beer+5 more
doaj
Effect of hypertension on low-density lipoprotein transport within a multi-layered arterial wall: modelling consistent with experiments [PDF]
The influence of hypertension on low-density lipoproteins intake into the arterial wall is an important factor for understanding mechanisms of atherosclerosis. It has been experimentally observed that the increased pressure leads to the higher level of the LDL inside the wall.
arxiv