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Lipoprotein apheresis to treat elevated lipoprotein (a)1 [PDF]

open access: hybridJournal of Lipid Research, 2016
An elevated plasma concentration of lipoprotein (a) [Lp(a)] is an independent risk factor for cardiovascular disease. Life style modification and currently available drugs either fail to effectively lower plasma Lp(a) levels or do not result in clinical ...
Elisa Waldmann, Klaus G. Parhofer
doaj   +7 more sources

Why Some Patients Undergoing Lipoprotein Apheresis Therapy Develop New Cardiovascular Events? [PDF]

open access: goldJournal of Cardiovascular Development and Disease, 2020
Lipoprotein apheresis (LA) is an effective tool to reduce cardiovascular events (CVEs) in high-risk patients with elevations of low density lipoprotein-cholesterol (LDL-C) and/or Lipoprotein(a) (Lp(a)).
Ulrich Julius   +4 more
doaj   +5 more sources

Case report: lipoprotein apheresis reduces the risk of cardiovascular events and prolongs pregnancy in a woman with severely elevated lipoprotein(a), cardiovascular disease, and a high risk of preeclampsia [PDF]

open access: yesFrontiers in Medicine, 2023
BackgroundPreeclampsia is a common and serious pregnancy-induced disease, with potential severe maternal and fetal complications. Recently, an increased lipoprotein (a) (Lp[a]) concentration, an important factor in cardiovascular diseases (CVDs ...
Joanna Marlȩga-Linert   +5 more
doaj   +3 more sources

Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia[S] [PDF]

open access: hybridJournal of Lipid Research, 2014
Lipoprotein-apheresis (apheresis) removes LDL-cholesterol in patients with severe dyslipidemia. However, reduction is transient, indicating that the long-term cardiovascular benefits of apheresis may not solely be due to LDL removal. Microparticles (MPs)
Katherine D. Connolly   +8 more
doaj   +4 more sources

Current Role of Lipoprotein Apheresis. [PDF]

open access: yesCurr Atheroscler Rep, 2019
Lipoprotein apheresis is a very efficient but time-consuming and expensive method of lowering levels of low-density lipoprotein cholesterol, lipoprotein(a)) and other apoB containing lipoproteins, including triglyceride-rich lipoproteins. First introduced almost 45 years ago, it has long been a therapy of "last resort" for dyslipidaemias that cannot ...
Thompson G, Parhofer KG.
europepmc   +7 more sources

Familial Hypercholesterolemia and Lipoprotein Apheresis. [PDF]

open access: yesJ Atheroscler Thromb, 2019
Lipoprotein apheresis has been developed as the treatment for refractory familial hypercholesterolemia (FH) to remove low-density lipoprotein (LDL), which is the main pathogenic factor. Currently, three procedures are available in Japan, including the plasma exchange, double-membrane filtration, and selective LDL adsorption.
Makino H   +6 more
europepmc   +5 more sources

Lipoprotein apheresis efficacy and challenges: single center experience [PDF]

open access: yesHematology, Transfusion and Cell Therapy, 2022
Introduction: Lipoprotein apheresis (LA) is an extracorporeal therapy which removes apolipoprotein B-containing particles from the circulation. We evaluated techniques and efficiency of lipoprotein apheresis procedures applied to patients with familial ...
Zehra Narlı Özdemir   +4 more
doaj   +2 more sources

Lipoprotein glomerulopathy treated with LDL-apheresis (Heparin-induced Extracorporeal Lipoprotein Precipitation system): a case report [PDF]

open access: yesJournal of Medical Case Reports, 2009
Introduction Lipoprotein glomerulopathy is a glomerulonephritis which was described for the first time by Saito in 1989 and is currently acknowledged as a separate nosological entity.
Rivasi Paolo   +6 more
doaj   +3 more sources

Changing from lipoprotein apheresis to evolocumab treatment lowers circulating levels of arachidonic acid and oxylipins [PDF]

open access: yesAtherosclerosis Plus
Background and aims: Previous studies have shown that lipoprotein apheresis can modify the plasma lipidome and pro-inflammatory and pro-thrombotic lipid mediators.
Chaoxuan Wang   +12 more
doaj   +2 more sources

Systematic Review of Low‐Density Lipoprotein Cholesterol Apheresis for the Treatment of Familial Hypercholesterolemia [PDF]

open access: goldJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundApheresis is an important treatment for reducing low‐density lipoprotein cholesterol (LDL‐C) in patients with familial hypercholesterolemia (FH). We systematically reviewed the current literature surrounding LDL‐C apheresis for FH.
Anthony Wang   +7 more
doaj   +2 more sources

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