Biomedicines, 2021 Lipoprotein(a) (Lp(a)) is a low density lipoprotein particle that is associated with poor cardiovascular prognosis due to pro-atherogenic, pro-thrombotic, pro-inflammatory and pro-oxidative properties.
Victoria A. Korneva +2 more
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Lipoprotein apheresis to treat elevated lipoprotein (a)1
Journal of Lipid Research, 2016 An elevated plasma concentration of lipoprotein (a) [Lp(a)] is an independent risk factor for cardiovascular disease. Life style modification and currently available drugs either fail to effectively lower plasma Lp(a) levels or do not result in clinical ...
Elisa Waldmann, Klaus G. Parhofer
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Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model [PDF]
, 2019 Introduction - Even if proprotein convertase subtilisin/kexin type 9 inhibitors have replaced lipoprotein apheresis in many patients, lipoprotein apheresis still is an important option in homozygous familial hypercholesterolemia, progressive ...
Randolf Hardersen +13 more
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Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia [PDF]
, 2014 Lipoprotein-apheresis (apheresis) removes LDL-cholesterol in patients with severe dyslipidemia. However, reduction is transient, indicating that the long-term cardiovascular benefits of apheresis may not solely be due to LDL removal. Microparticles (MPs)
D Aled Rees (10871627) +8 more
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Acute effects of low density lipoprotein apheresis on metabolic parameters of apolipoprotein B
Journal of Lipid Research, 2000 Apheresis is a treatment option for patients with severe hypercholesterolemia and coronary artery disease. It is unknown whether such therapy changes kinetic parameters of lipoprotein metabolism, such as apolipoprotein B (apoB) secretion rates ...
Klaus G. Parhofer +3 more
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Urinary Neopterin and Microalbuminuria in Patients Treated by Low-density Lipoprotein Apheresis
Pteridines, 2005 Low-density lipoprotein (LDL)-apheresis is a method of extracorporeal elimination of LDL-cholesterol in patients with severe primary lipoprotein disorders.
Cermanová Melanie +8 more
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Mechanism, clinical consequences, and management of dyslipidemia in children with nephrotic syndrome [PDF]
Childhood Kidney Diseases, 2022 Dyslipidemia in nephrotic syndrome (NS) is often characterized by marked increases in the levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol, and other lipoproteins, such as very low-density lipoprotein, intermediate-density ...
Hee Sun Baek
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LDL‐aférese no tratamento de hipercolesterolemia familiar: experiência do Hospital Santo António
Revista Portuguesa de Cardiologia, 2015 Resumo: Introdução: A hipercolesterolemia manifestada pelos níveis elevados de colesterol das lipoproteínas de baixa densidade constitui um fator de risco major para o desenvolvimento e progressão da doença aterosclerótica prematura.A adsorção direta de
Isabel Palma +8 more
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Nonpharmacological Lipoprotein Apheresis Reduces Arterial Inflammation in Familial Hypercholesterolemia [PDF]
, 2014 BackgroundPatients with familial hypercholesterolemia (FH) are characterized by elevated atherogenic lipoprotein particles, predominantly low-density lipoprotein cholesterol (LDL-C), which is associated with accelerated atherogenesis and increased ...
Lobatto, Mark E. +19 more
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LDL-Apheresis: Technical and Clinical Aspects
The Scientific World Journal, 2012 The prognosis of patients suffering from severe hyperlipidemia, sometimes combined with elevated lipoprotein (a) levels, and coronary heart disease refractory to diet and lipid-lowering drugs is poor. For such patients, regular treatment with low-density
Rolf Bambauer +4 more
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