Results 41 to 50 of about 130,554 (162)

Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence

Journal of Clinical Apheresis, Volume 41, Issue 5, October 2026.
ABSTRACT Chronic limb‐threatening ischemia (CLTI), a severe manifestation of peripheral artery disease, is particularly prevalent among patients receiving maintenance hemodialysis (HD) and is associated with poor limb and survival outcomes. Low‐density lipoprotein (LDL) apheresis, including Rheocarna, is used as adjunctive therapy for refractory CLTI ...
Yusuke Ishizuka, Genshin Sato, Shizuka Ishigaki, Ryo Enoki, Kako Kajiwara, Akihiko Nakasato, Sosuke Kinomura, Saori Kin, Yuji Noguchi, Daisuke Yoshizawa, Koichi Kikuchi, Michiaki Abe, Koki Kumagai, Tetsuhiro Tanaka, Koji Okamoto   +14 more
wiley   +1 more source

Preoperative Low-Density Lipoprotein Apheresis for Preventing Recurrence of Focal Segmental Glomerulosclerosis after Kidney Transplantation

Journal of Transplantation, 2018
Background. Focal segmental glomerulosclerosis (FSGS) often develops rapidly and frequently progresses to renal failure, while the recurrence rate after kidney transplantation is 20–50%.
Akihito Sannomiya, Toru Murakami, Ichiro Koyama, Kosaku Nitta, Ichiro Nakajima, Shohei Fuchinoue   +5 more
doaj   +1 more source

Mitochondrial DNA mutations are associated with impaired oxidative phosphorylation and enhanced imatinib response in chronic myeloid leukemia

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Mitochondrial DNA (mtDNA) mutations are frequently observed in cancer, but their clinical and functional significance in chronic myeloid leukemia (CML) remains incompletely defined. Here, we show that a distinct mtDNA mutational landscape is associated with mitochondrial metabolic programs and response to imatinib therapy in CML.
Ilaria S. Pagani, Vaidehi Krishnan, John F. Ouyang, Chung H. Kok, BeiJun Chen, Kian Leong Lee, Cong M. Pham, Paul Wang, Elyse Page, Phuong Dang, Verity A. Saunders, Jane James, Kelly Lim, Stefano Mangiola, Yingnan Gao, Naranie Shanmuganathan, Agnes Yong, Susan Branford, Charles Chuah, David T. Yeung, Deborah L. White, Vignir G. Helgason, Daniel Thomas, S. Tiong Ong, Timothy P. Hughes, David M. Ross   +25 more
wiley   +1 more source

Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemia1

Journal of Lipid Research, 2012
We measured oxidized phospholipids (OxPL), lipoprotein (a) [Lp(a)], and lipoprotein-associated phospholipase A2 (Lp-PLA2) pre- and postapheresis in 18 patients with familial hypercholesterolemia (FH) and with low(∼10 mg/dl; range 10–11 mg/dl ...
Kiyohito Arai, Alexina Orsoni, Ziad Mallat, Alain Tedgui, Joseph L. Witztum, Eric Bruckert, Alexandros D. Tselepis, M. John Chapman, Sotirios Tsimikas   +8 more
doaj   +1 more source

A retrospective analysis of clinical use of alirocumab in lipoprotein apheresis patients [PDF]

, 2020
BACKGROUND: The previously published ODYSSEY ESCAPE trial demonstrated a significant reduction in the use of lipoprotein apheresis for heterozygous familial hypercholesterolemia (HeFH) patients when placed on alirocumab 150 mg every 2 weeks.
Wooten, Michael, Hemphill, Linda, Dunbar, Richard L, Wilson, Gerald, Dacus, Kelley, Goldberg, Anne C, Moriarty, Patrick M, Babirak, Stephan P, Minchew, Heather, Dutton, Julie-Ann, Iydroose, Mohamed   +10 more
core   +1 more source

Pregnancy in a Woman with Homozygous Familial Hypercholesterolemia Not on Low-Density Lipoprotein Apheresis

American Journal of Perinatology Reports, 2012
Pregnancy in women with homozygous familial hypercholesterolemia (FH) has been rarely reported and might pose risks on the mother and her fetus. Although most reported cases remained on low-density lipoprotein (LDL) apheresis, there are no clear ...
Akl C. Fahed, Anwar H. Nassar
doaj   +1 more source

Delivery Systems for Therapeutic Genome Editing: Challenges, Innovations, and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Schematic illustration of four emerging CRISPR–Cas delivery platforms defined by distinct design principles and structural features: virus‐mimicking nanosystems (e.g., VLPs), cell‐derived extracellular vesicles, cell‐penetrating peptides, and stimuli‐responsive scaffolds. These platforms enable spatiotemporally controlled delivery of RNPs, mRNA, or DNA
Meijia Yang, Yiqiong Song, Ziyang Wang, Ke Chao, Lifeng Li, Xu Zhang, Xiaoran Duan, Chenglong Yu, Ruyue Xue, Jie Zhao   +9 more
wiley   +1 more source

A case report of soluble A antigen confounding the blood type in a haplo‐identical hematopoietic stem cell transplant patient with graft‐versus‐host disease

Transfusion, Volume 66, Issue 7, Page 1438-1443, July 2026.
Abstract Background ABO‐incompatible (ABOi) hematopoietic stem cell transplantation (HSCT) is often associated with ABO discrepancies post‐HSCT. Re‐emergence of the patient's original type post‐HSCT may signal graft loss, disease relapse, recent transfusion, or soluble ABO antigen.
Sheri Hugan, Nada Naiyer, Laura Cooling
wiley   +1 more source

The world apheresis association registry, 2023 update

, 2023
The WAA apheresis registry contains data on more than 140,000 apheresis procedures conducted in 12 different countries. The aim is to give an update of indications, type and number of procedures and adverse events (AEs).
Kielstein, Jan, Astrid Aandahl, Seval, Guldane Cengiz,, Le Poole, Kaatje,, Michael Ott, Fredrik Toss, Griskevicius, Antanas,, Bojanic, Ines,, Aandahl, Astrid,, Griskevicius, Antanas, Derfler, Kurt, Dries Deeren, Derfler, Kurt,, Gösta Berlin, Vrielink, Hans,, Prophet, Heinrich,, Judita Audzijoniene, Milan Blaha, Audzijoniene, Judita,, Heinrich Prophet, Guldane Cengiz Seval, Audzijoniene, Judita, Elizabeth Newman, Volker Witt, Blahutova, Sarka, Strineholm, Virginia, Hans Vrielink, Stegmayr, Bernd,, Ines Bojanic, Newman, Elizabeth,, Hrdlickova, Radomira,, Zdenka Bhuiyan-Ludvikova, Witt, Volker, Gasova, Zdenka,, Blaha, Milan,, Thomas Nilsson, Blaha, Milan, Berlin, Gösta, Berlin, Gösta,, Bhuiyan-Ludvikova, Zdenka, Hrdlickova, Radomira, Lanska, Miriam,, Toss, Fredrik, Ilhan, Osman,, Blahutova, Sarka,, Glatt, Tanya, Tanya Glatt, Strineholm, Virginia,, Kaatje Le Poole, Le Poole, Kaatje, Lanska, Miriam, Bojanic, Ines, Newman, Elizabeth, Ilhan, Osman, Radomira Hrdlickova, Antanas Griskevicius, Ott, Michael, Gasova, Zdenka, Seval, Guldane Cengiz, Miriam Lanska, Zdenka Gasova, Virginia Strineholm, Bernd Stegmayr, Glatt, Tanya,, Kielstein, Jan,, Toss, Fredrik,, Deeren, Dries,, Prophet, Heinrich, Nilsson, Thomas, Deeren, Dries, Jan Kielstein, Osman Ilhan, Aandahl, Astrid, Vrielink, Hans, Ott, Michael,, Kurt Derfler, Nilsson, Thomas,, Witt, Volker,, Sarka Blahutova, Stegmayr, Bernd, Bhuiyan-Ludvikova, Zdenka,   +80 more
core   +1 more source

Impact of LDL apheresis on atheroprotective reverse cholesterol transport pathway in familial hypercholesterolemia

Journal of Lipid Research, 2012
In familial hypercholesterolemia (FH), low HDL cholesterol (HDL-C) levels are associated with functional alterations of HDL particles that reduce their capacity to mediate the reverse cholesterol transport (RCT) pathway.
Alexina Orsoni, Elise F. Villard, Eric Bruckert, Paul Robillard, Alain Carrie, Dominique Bonnefont-Rousselot, M. John Chapman, Geesje M. Dallinga-Thie, Wilfried Le Goff, Maryse Guerin   +9 more
doaj   +1 more source