Results 61 to 70 of about 130,554 (162)

The lipid- and lipoprotein- [LDL-Lp(a)] apheresis techniques. Updating [PDF]

, 2012
Therapeutic plasmapheresis allows the extracorporeal removal of plasmatic lipoproteins (Lipid-apheresis) (LA). It can be non selective (non specific), semi - selective or selective low density lipoprotein-lipoprotein(a) (specific [LDL- Lp(a)] apheresis) (
Perrone, G., Stefanutti, Claudia, Vivenzio, Antonio, D'Alessandri, Giovanna, Di Giacomo, Stefania, Morozzi, Claudia   +5 more
core   +1 more source

Acute and chronic effects on cholesterol biosynthesis of LDL-apheresis with or without concomitant HMG-CoA reductase inhibitor therapy.

Journal of Lipid Research, 1994
To determine the acute and long-term effects of low density lipoprotein (LDL) reduction on cholesterol biosynthesis, we studied changes in the cholesterol precursors mevalonic acid (MVA) and lathosterol in patients with heterozygous familial ...
M Pfohl, R P Naoumova, C Klass, W Knisel, B Jakober, T Risler, G R Thompson   +6 more
doaj   +1 more source

Intensive Combination LDL-Lowering Therapy in a Patient With Homozygous Familial Hypercholesterolemia

JACC: Case Reports
We present a young boy with a diagnosis of homozygous familial hypercholesterolemia who presented with statin and ezetimibe resistance. The patient received lipoprotein apheresis at 6 years of age.
Hayato Tada, MD, Hirofumi Okada, MD, Masa-aki Kawashiri, MD, Masayuki Takamura, MD   +3 more
doaj   +1 more source

A case report of the cascade filtration system: A safe and effective method for low-density lipoprotein apheresis during pregnancy

, 2008
PubMedID: 18937724Women with familial hypercholesterolemia (FH) should be treated effectively during pregnancy, as elevated low-density lipoprotein cholesterol (LDL-C) levels may result in life-threatening consequences.
Haydardedeoglu B., Guvenc B., Tekinturhan F., Ertorer M.E.   +3 more
core   +1 more source

Serum Proteomic Analysis of Lipoprotein Apheresis in Patients with Hyperlipidemia

Zhipu Xuebao
Hyperlipidemia is a chronic disease characterized by elevated cholesterol and triglyceride levels in the blood, and has been identified as a common risk factor for many cardiovascular diseases, such as atherosclerosis, heart disease, stroke and obesity ...
Dong XU, Ye-xiao-qing YANG, Rong LIU, Zhong-han HU, Ding-feng LYU, Ke-qi TANG   +5 more
doaj   +1 more source

In vivo CAR therapies: Turning the patient into their own CAR factory

HemaSphere, Volume 10, Issue 5, May 2026.
Abstract Over the past decade, ex vivo autologous chimeric antigen receptor (CAR)‐T‐cell therapies have reshaped the treatment of B‐cell malignancies. Despite their remarkable clinical efficacy, their application remains limited by complex manufacturing processes, demanding logistics, long turnaround times, and substantial costs. In vivo CAR approaches
François Vilcot, Carole‐Anne Brugère, Jaime Fuentealba, Roch Houot   +3 more
wiley   +1 more source

Diagnosis and Metabolic Management of Adult Refsum Disease: Guidance From the Medical and Scientific Committee of Global DARE (Defeat Adult Refsum Everywhere)

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Adult Refsum disease (ARD; OMIM 266510) is a degenerative autosomal recessive condition typically diagnosed in adulthood. It affects visual, auditory and nervous system function. It is characterised by plasma, neuro‐ophthalmological and adipose tissue accumulation of the dietary‐derived phytanic acid (PA).
Radha Ramachandran, Raphael Buttigieg, Florian Eichler, Bart P. Leroy, Omar Mahroo, Rachel M. Huckfeldt, Sarah Firman, Eleanor Baldwin, Kristie DeMarco, Susan Kuranoff, Amena Fine, Reinhard Klingel, Sacha Ferdinandusse, Joseph G. Hacia, Ronald J. Wanders, Anthony S. Wierzbicki   +15 more
wiley   +1 more source

A lipidomic analysis approach in patients undergoing lipoprotein apheresis

, 2016
Lipoprotein apheresis such as heparin-induced extracorporal LowDensityLipoprotein (LDL) Cholesterol precipitation (HELP) reduces apolipoprotein B-containing lipoproteins, most importantly low-density-lipoprotein (LDL), and lipoprotein (a) [Lp(a)].
Kiesler, S., Steinhagen-Thiessen, E., Bismarck, M., Schmoecker, C., Rothe, M., Kassner, U., Weylandt, K.H.   +6 more
core   +1 more source

Aggressive lipid-lowering therapy before and after revascularization in patients with stable coronary artery disease

Медицинский совет, 2013
The review presents data on the effectiveness of lipid profile correction with maximum doses of statins, primarily atorvastatin, and lipoprotein apheresis.
R. N. Adzhiev, M. S. Safarova, M. V. Yezhov, Y. G. Matchin   +3 more
doaj   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source