Results 11 to 20 of about 280,456 (250)

Lipoprotein apheresis affects the concentration of extracellular vesicles in patients with elevated lipoprotein (a) [PDF]

Scientific Reports
Lipoprotein apheresis (LA) is a therapeutic option for hyperlipoproteinemia(a) (hyper-Lp(a)) and atherosclerotic cardiovascular disease (ASCVD). LA improves blood rheology, reduces oxidative stress parameters and improves endothelial function.
Joanna Marlęga-Linert, Aleksandra Gąsecka, Edwin van der Pol, Agnieszka Kuchta, Krzysztof J. Filipiak, Marcin Fijałkowski, Marcin Gruchała, Rienk Nieuwland, Agnieszka Mickiewicz   +8 more
doaj   +3 more sources

Lipoprotein(a) Lowering-From Lipoprotein Apheresis to Antisense Oligonucleotide Approach. [PDF]

J Clin Med, 2020
It is well-known that elevated lipoprotein(a)—Lp(a)—levels are associated with a higher risk of cardiovascular (CV) mortality and all-cause mortality, although a standard pharmacotherapeutic approach is still undefined for patients with high CV risk dependent on hyperlipoproteinemia(a). Combined with high Lp(a) levels, familial hypercholesterolemia (FH)
Greco MF, Sirtori CR, Corsini A, Ezhov M, Sampietro T, Ruscica M.   +5 more
europepmc   +6 more sources

Monitoring of up to 15 years effects of lipoprotein apheresis on lipids, biomarkers of inflammation, and soluble endoglin in familial hypercholesterolemia patients [PDF]

Orphanet Journal of Rare Diseases, 2021
Background Lipoprotein apheresis (LA) is considered as an add-on therapy for patients with familial hypercholesterolemia (FH). We aimed to analyze the data collected in the last 15 years from FH patients treated with LA, to elucidate the benefit of this ...
J. Víšek, M. Bláha, V. Bláha, M. Lášticová, M. Lánska, C. Andrýs, J. Duintjer Tebbens, Ivone Cristina Igreja e Sá, K. Tripská, M. Vicen, I. Najmanová, P. Nachtigal   +11 more
doaj   +3 more sources

Flaxseed (Linum Usitatissimum L.) Supplementation in Patients Undergoing Lipoprotein Apheresis for Severe Hyperlipidemia-A Pilot Study. [PDF]

Nutrients, 2020
Being rich in polyunsaturated fatty acids, flaxseed (Linum usitatissimum L.) is thought to be able to decrease lipid levels and dampen inflammation. In this pilot study, we aimed to determine whether flaxseed supplementation could improve the profiles of
Kanikowska D, Korybalska K, Mickiewicz A, Rutkowski R, Kuchta A, Sato M, Kreft E, Fijałkowski M, Gruchała M, Jankowski M, Bręborowicz A, Witowski J.   +11 more
europepmc   +4 more sources

Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis [PDF]

São Paulo Medical Journal, 1997
Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo ...
Madalena Nunes da Silva Pares, Elbio Antonio D'Amico, José Mauro Kutner, Dalton de Alencar Fischer Chamone, Sergio Paulo Bydlowski   +4 more
doaj   +2 more sources

Desialylation of platelet surface glycans enhances platelet adhesion to adsorbent polymers for lipoprotein apheresis. [PDF]

Int J Artif Organs, 2021
Background: Lipoprotein apheresis is an important therapeutic option in homozygous familial hypercholesterolemia, progressive atherosclerosis, or when depletion of lipoprotein(a) is indicated.
Lauková L, Weiss R, Semak V, Weber V.
europepmc   +4 more sources

Lipoprotein apheresis: an update [PDF]

Clinical Lipidology, 2013
Since the 1980s, several lipoprotein apheresis methods that eliminate atherogenic lipoproteins (LDL and lipoprotein(a) [Lp(a)]) have been developed. These methods are based on the following principles: precipitation, adsorption and filtration. In Dresden (Germany), we started to perform extracorporeal treatment in 1990; in the 1980s we were working as ...
Ulrich Julius, Sabine Fischer, Ulrike Schatz, Bernd Hohenstein, Stefan R. Bornstein   +4 more
openalex   +2 more sources

Oxidised LDL and Anti-Oxidised LDL Antibodies Are Reduced by Lipoprotein Apheresis in a Randomised Controlled Trial on Patients with Refractory Angina and Elevated Lipoprotein(a) [PDF]

Antioxidants, 2021
Aims: An abundance of epidemiological evidence demonstrates that elevated lipoprotein(a) (Lp(a)) represents a significant contributing risk factor towards the development of cardiovascular disease.
Tina Z. Khan, Adam Hartley, Dorian Haskard, Mikhail Caga-Anan, Dudley J. Pennell, Peter Collins, Mahmoud Barbir, Ramzi Khamis   +7 more
doaj   +2 more sources

Urinary Neopterin and Microalbuminuria in Patients Treated by Low-density Lipoprotein Apheresis [PDF]

Pteridines, 2005
Low-density lipoprotein (LDL)-apheresis is a method of extracorporeal elimination of LDL-cholesterol in patients with severe primary lipoprotein disorders.
Cermanová Melanie, Melichar Bohuslav, Solichová Dagmar, Bláha Milan, Bláha Vladimir, Blazek Martin, Mašín Vladimir, Cerman Jaroslav, Zadák Zdenek   +8 more
doaj   +2 more sources

Beyond cholesterol—pleiotropic effects of lipoprotein apheresis

Therapeutic Apheresis and Dialysis, 2022
AbstractCardiovascular disease is a leading cause of mortality worldwide, which is caused mainly by atherosclerosis, a chronic inflammatory disease of blood vessels. Therefore, atherosclerosis represents a complex disorder, which induces damage or imbalance on different levels: for example, genes, cytokines, lipoproteins, cells, vessels, and organs ...
Volker J. J. Schettler, Elke Schettler
openaire   +4 more sources