Results 71 to 80 of about 3,148 (231)

Aggressive lipid-lowering therapy before and after revascularization in patients with stable coronary artery disease

Медицинский совет, 2013
The review presents data on the effectiveness of lipid profile correction with maximum doses of statins, primarily atorvastatin, and lipoprotein apheresis.
R. N. Adzhiev, M. S. Safarova, M. V. Yezhov, Y. G. Matchin   +3 more
doaj   +1 more source

A novel small molecule phagocytosis inhibitor, KB‐208, ameliorates ITP in mouse models with similar efficacy as IVIG

Transfusion, Volume 64, Issue 12, Page 2233-2240, December 2024.
Abstract Background The characteristic feature of immune cytopenias involves the process of extravascular phagocytosis, wherein macrophages in the spleen and/or liver engage in the destruction of blood cells that have been opsonized by auto‐ or alloantibodies.
Melika Loriamini, Melissa M. Lewis‐Bakker, Beth Binnington, Lakshmi P. Kotra, Donald R. Branch   +4 more
wiley   +1 more source

Debiased Inference on Heterogeneous Quantile Treatment Effects with Regression Rank-Scores [PDF]

arXiv, 2021
Understanding treatment effect heterogeneity is vital to many scientific fields because the same treatment may affect different individuals differently. Quantile regression provides a natural framework for modeling such heterogeneity. We propose a new method for inference on heterogeneous quantile treatment effects in the presence of high-dimensional ...
arxiv  

Rheocarna Effectively Treats Oral Medicinal Therapy‐Resistant Cutaneous Symptoms and Renal Failure Induced by Cholesterol Crystal Embolism

Clinical Case Reports, Volume 12, Issue 11, November 2024.
ABSTRACT An 80‐year‐old man presented to our hospital with worsening renal function and ambulation difficulties due to lower extremity symptoms that included livedo reticularis, gangrene, cyanosis, and ulcers in his legs. The patient was diagnosed with a cholesterol crystal embolism.
Akinori Satake, Takahiro Tokuda, Hirofumi Ohashi, Yusuke Nakano, Akio Kodama, Tetsuya Amano   +5 more
wiley   +1 more source

PCSK9 Inhibitors: The Evolving Future

Health Science Reports, Volume 7, Issue 11, November 2024.
ABSTRACT Introduction PCSK9 inhibitors are a novel class of medications that lower LDL cholesterol (LDL‐C) by increasing LDL receptor activity, promoting clearance of LDL‐C from the bloodstream. Over the years, PCSK9 inhibitors have been explored as adjunct therapies to statins or as monotherapy in high‐risk cardiovascular patients.
Bijay Mukesh Jeswani, Shubhangi Sharma, Sawai Singh Rathore, Abubakar Nazir, Rohit Bhatheja, Kapil Kapoor   +5 more
wiley   +1 more source

Single Low-Density Lipoprotein Apheresis Does Not Improve Vascular Endothelial Function in Chronically Treated Hypercholesterolemic Patients

International Journal of Vascular Medicine, 2016
Objective. To investigate vascular endothelial function (VEF) responses to a single low-density lipoprotein (LDL) apheresis session in hypercholesterolemic patients undergoing chronic treatment. Methods. We measured brachial artery flow-mediated dilation
Kevin D. Ballard, Eunice Mah, Yi Guo, Richard S. Bruno, Beth A. Taylor, Jo Ellen Beam, Donna M. Polk, Paul D. Thompson   +7 more
doaj   +1 more source

Stability of discoidal high-density lipoprotein particles [PDF]

arXiv, 2013
Motivated by experimental and numerical studies revealing that discoidal high-density lipoprotein (HDL) particles may adopt flat elliptical and nonplanar saddle-like configurations, it is hypothesized that these might represent stabilized configurations of initially unstable flat circular particles. A variational description is developed to explore the
arxiv  

Perioperative management in pediatric domino liver transplantation for metabolic disorders: A narrative review

Pediatric Anesthesia, Volume 34, Issue 11, Page 1107-1118, November 2024.
Abstract Domino liver transplantation and domino‐auxiliary partial orthotopic liver transplantation are emerging techniques that can expand the liver donor pool and provide hope for children with liver disease. The innovative technique of domino liver transplantation has emerged as a pioneering strategy, capitalizing on structurally preserved livers ...
Ahmed Uslu, Nedim Çekmen, Adnan Torgay, Mehmet Haberal   +3 more
wiley   +1 more source

LDL‐aférese no tratamento de hipercolesterolemia familiar: experiência do Hospital Santo António

Revista Portuguesa de Cardiologia, 2015
Resumo: Introdução: A hipercolesterolemia manifestada pelos níveis elevados de colesterol das lipoproteínas de baixa densidade constitui um fator de risco major para o desenvolvimento e progressão da doença aterosclerótica prematura.A adsorção direta de
Isabel Palma, Ana Rita Caldas, Isabel Mangas Palma, José Alexandre Queirós, Anselmo Madureira, José Carlos Oliveira, Paulo Palma, Carlos Correia, Maria Helena Ramos   +8 more
doaj  

Platelet aggregation and lipoprotein levels in a patient with familial hypercholescholesterolemia after selective LDL-apheresis

São Paulo Medical Journal
Platelet aggregation was studied in a patient with familial hypercholesterolemia immediately after aphereis selective for low-density lipoprotein (LDL), a lipid-lowering procedure.This treatment reduced plasmatic levels of total and LDL-cholesterol, apo ...
Madalena Nunes da Silva Pares, Elbio Antonio D'Amico, José Mauro Kutner, Dalton de Alencar Fischer Chamone, Sergio Paulo Bydlowski   +4 more
doaj   +1 more source