Results 141 to 150 of about 96,115 (285)
Alipogene tiparvovec: a long journey of risk-benefit ratio assessment of gene therapy products
According to EMA, advanced therapy medicinal products include, inter alia, therapeutic systems containing nucleic acids used for replacement or repair of genetic defects.
R. N. Alyautdin +6 more
doaj
Abstract INTRODUCTION The PSEN1E280A mutation causes autosomal dominant Alzheimer's disease (ADAD) with predictable onset, enabling presymptomatic studies. Extracellular vesicles (EVs) are emerging biomarkers of cognitive decline, but their role in early ADAD is unclear.
Lina Pineda‐Lopez +14 more
wiley +1 more source
Association of Remnant Cholesterol With Self‑Reported Trouble Sleeping and Mediation by Depression
Remnant cholesterol was positively and linearly associated with self‐reported trouble sleeping in U.S. adults, and depression partially mediated this relationship. Monitoring remnant cholesterol may help identify individuals at higher risk of sleep problems and related cardiometabolic consequences.
Qichao Yang +3 more
wiley +1 more source
Effects of Platelet-Derived Growth Factor on the Synthesis of Lipoprotein Lipase in Human Monocyte–Derived Macrophages [PDF]
Toshimori Inaba +9 more
openalex +1 more source
Mechanisms of Energy Balance in Obesity
The proper understanding of obesity requires a multifaceted approach. Behavioral considerations of eating and activity patterns do not account for the large between- and within-subjects variance associated with the energy-balance equation.
McMinn, Mark R.
core
Sumac (Rhus coriaria L.) and Human Metabolic Health: A Systematic Review and Meta‐Analysis
Sumac (Rhus coriaria L.) supplementation enhances glycemic control and lipid metabolism, indicating potential cardiometabolic benefits in reducing cardiovascular disease risk factors. ABSTRACT Background Rhus coriaria L. (Anacardiaceae), known as Sumac, is a commonly used spice, which is rich in various classes of phytochemicals including flavonoids ...
Ali Jafari +9 more
wiley +1 more source
Effects of Clinofibrate on Lipoprotein Lipase Activity
Mitsunobu Kawamura +5 more
openalex +2 more sources
Integrated framework for tirzepatide in HFpEF management. Through metabolic, haemodynamic, structural and anti‐inflammatory pathways, tirzepatide modifies the disease trajectory of HFpEF, leading to improvements in symptoms, functional capacity and reduction in HF events.
Hamza A. Abdul‐Hafez +9 more
wiley +1 more source
Sulfated Polysaccharides in the Hallmarks of Metabolic Syndrome: Functions and Mechanisms
The SPs sources are very diverse, including various fishes, sea cucumbers, seaweeds, etc. These SPs are able to improve the glucose and lipid metabolism disorders, hormonal dysregulation, oxidative stress, inflammatory response, complications, and gut homeostasis of MetS by regulating biochemical indicators related to MetS. ABSTRACT Metabolic syndrome (
Fuqiang Zhao +9 more
wiley +1 more source
Abnormal Lipoprotein Lipase in Familial Exogenous Hypertriglyceridemia [PDF]
Paul H. Schreibman +3 more
openalex +1 more source

