Results 121 to 130 of about 46,480 (224)

Lipoprotein lipase: regulation and role in lipoprotein metabolism [PDF]

Proceedings of the Nutrition Society, 1997
T, Olivecrona, M, Hultin, M, Bergö, G, Olivecrona   +3 more
openaire   +2 more sources

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Non-remnant triglyceride-rich lipoproteins due to lipoprotein lipase deficiency increase atherosclerosis in mice. [PDF]

Nat Commun
Cabodevilla AG, Izquierdo MC, Basu D, Younis W, Tirumalasetty MB, Miao QR, Nasias D, Kanter JE, Ho TWW, Gjini J, Fisher E, Kim J, Lee WL, Bornfeldt K, Goldberg IJ.   +14 more
europepmc   +1 more source

The changing epidemiology of human type 2 diabetes–associated atherosclerosis: Pathophysiological mechanisms and emerging treatment possibilities

Journal of Internal Medicine, Volume 300, Issue 2, Page 131-152, August 2026.
Abstract Type 2 diabetes (T2D) is a major global health concern strongly associated with atherosclerosis and subsequent macrovascular complications. These complications are the leading cause of death among T2D patients. Despite a decline in cardiovascular events over the last decade, individuals with T2D still have an approximately doubled risk ...
Dania Al‐Sharify, Jiangming Sun, Andreas Edsfeldt   +2 more
wiley   +1 more source

Changes to small RNA expression in macrophages in response to very low-density lipoprotein lipid hydrolysis by lipoprotein lipase and NADPH oxidase inhibition. [PDF]

BMC Res Notes
Tijani MO, Chia EW, Cotter NSM, Peña-Castillo L, Brown RJ.   +4 more
europepmc   +1 more source

Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction–Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole‐Body Fat Metabolism, and Organ‐Specific Lipid Deposition

Obesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Introduction This narrative review explores the epidemiological evidence and potential underlying pathophysiological defects underlying the disproportionately greater risk of Type 2 diabetes (T2D) and cardiometabolic disease in people of South Asian and African Caribbean ancestry compared with White Europeans.
Daniel J. Cuthbertson, Martin Whyte, Alex E. Henney, Uazman Alam, Louise Goff, Barbara A. Fielding, A. Margot Umpleby   +6 more
wiley   +1 more source

Hypertriglyceridemia in Apoa5-/- mice results from reduced amounts of lipoprotein lipase in the capillary lumen. [PDF]

J Clin Invest, 2023
Yang Y, Beigneux AP, Song W, Nguyen LP, Jung H, Tu Y, Weston TA, Tran CM, Xie K, Yu RG, Tran AP, Miyashita K, Nakajima K, Murakami M, Chen YQ, Zhen EY, Kim JR, Kim PH, Birrane G, Tontonoz P, Ploug M, Konrad RJ, Fong LG, Young SG.   +23 more
europepmc   +1 more source

Lipoprotein lipase deficiency: heterozygotes match homozygotes in severity. [PDF]

Arch Med Sci
Szczęśniak D, Bednarska-Makaruk M, Drgas O, Kowalczyk K, Kacprzak MM, Aleksandrowicz P, Kotuła L, Mroczek M.   +7 more
europepmc   +1 more source

What is the phenotype of heterozygous lipoprotein lipase deficiency? [PDF]

Curr Opin Lipidol
Hegele RA.
europepmc   +1 more source

Lipoprotein Lipase/Apolipoprotein Cll Gene Polymorphism in Kurdish Patients With Severe Hypertriglyceridemia. [PDF]

Cureus, 2023
Hussein K, Salih S, Al-Timimi D.
europepmc   +1 more source