Results 111 to 120 of about 46,480 (224)

GPIHBP1 on oligodendrocytes binds lipoprotein lipase within the human brain. [PDF]

open access: yesProc Natl Acad Sci U S A
Liu M   +18 more
europepmc   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang   +6 more
wiley   +1 more source

Convergent digestive adaptation to resource limitation in an insular lizard across a microgeographic archipelago

open access: yesJournal of Animal Ecology, Volume 95, Issue 8, Page 1372-1385, August 2026.
Replicated mainland–islet populations of the Skyros wall lizard reveal consistent divergence in digestive physiology, including gut morphology, passage time, digestive efficiency and enzyme activity. These results show how ecological variation in resource availability can shape digestive performance across populations in insular environments.
Aikaterini Reppa   +8 more
wiley   +1 more source

Imaging the ANGPTL3/8-mediated regulation of lipoprotein lipase in the heart. [PDF]

open access: yesJ Lipid Res, 2023
Yang Y   +4 more
europepmc   +1 more source

Survodutide for the Treatment of Obesity Disease in Japanese Participants: Rationale, Design and Baseline Characteristics of the Phase 3 SYNCHRONIZE‐JP Trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6595-6606, August 2026.
ABSTRACT Aims There is an unmet need for effective pharmacotherapy for obesity disease management in Japan. Survodutide is a novel glucagon receptor/glucagon‐like peptide‐1 receptor (GLP‐1R) dual agonist with the potential to induce greater weight reductions than GLP‐1R mono‐agonists. We report the design and baseline participant characteristics of the
Koutaro Yokote   +10 more
wiley   +1 more source

Reversibly reduced lipoprotein lipase in APOA5 c.553G>T-related hypertriglyceridemia successfully treated with pemafibrate. [PDF]

open access: yesEndocrinol Diabetes Metab Case Rep
Miyauchi S   +12 more
europepmc   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6509-6532, August 2026.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano   +4 more
wiley   +1 more source

The Ongoing Utility of lipoprotein lipase activity in diagnosing familial Chylomicronemia Syndrome. [PDF]

open access: yesBiochem Biophys Rep
Fariña G   +7 more
europepmc   +1 more source

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