Schematic of the mechanism of fetuin‐b mediated high‐fat diet‐induced hepatic steatosis in Larimichthys crocea. Lipid overload triggers C/EBPα‐mediated fetuin‐b upregulation. Fetuin‐b drives hepatic lipid accumulation by reprogramming lipid metabolism and inhibiting Plin2 ubiquitination to stabilize lipid droplets, identifying it as a potential ...
Yanan Shen +8 more
wiley +1 more source
A mechanistic basis is proposed for how variation in protein sequence perturbs cholesterol handling in Niemann–Pick type C2 (NPC2) protein. A relatively rigid hydrophobic core stabilizes cholesterol binding, a flexible but coordinated rim enables controlled access and productive transfer of cholesterol, and coordinated loop motions modulate pocket ...
Smit Patel, Nadia Elghobashi‐Meinhardt
wiley +1 more source
Cardiac Metabolomic Alterations in Diabetes: Interplay with Lipoprotein Lipase-A Systematic Review. [PDF]
Gu J, Han X, Chen X, Lyu A, Cheung KCP.
europepmc +1 more source
Preheparin Serum Lipoprotein Lipase Mass as a Coronary Risk Factor in Patients With Chronic Kidney Disease. [PDF]
Hitsumoto T.
europepmc +1 more source
Imaging the ANGPTL3/8-mediated regulation of lipoprotein lipase in the heart. [PDF]
Yang Y +4 more
europepmc +1 more source
Reversibly reduced lipoprotein lipase in APOA5 c.553G>T-related hypertriglyceridemia successfully treated with pemafibrate. [PDF]
Miyauchi S +12 more
europepmc +1 more source
Non-remnant triglyceride-rich lipoproteins due to lipoprotein lipase deficiency increase atherosclerosis in mice. [PDF]
Cabodevilla AG +14 more
europepmc +1 more source
The Ongoing Utility of lipoprotein lipase activity in diagnosing familial Chylomicronemia Syndrome. [PDF]
Fariña G +7 more
europepmc +1 more source
Global knockout of VEGFB improves lipoprotein lipase activity leading to an improved lipid profile during diabetes. [PDF]
Wang H +4 more
europepmc +1 more source

