Results 201 to 210 of about 89,489 (249)
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The Indian Journal of Pediatrics, 2020
To analyse the clinical and molecular spectrum of Lipoprotein Lipase (LPL) deficiency and to highlight the effect of a cost-effective indigenous diet for management of this disorder.This is a single-centre retrospective study. Fifteen patients from 14 kindreds with severe hypertriglyceridemia (more than 1000 mg/dl) were evaluated for a period of 12.5 y
Shwetha Kuthiroly +6 more
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To analyse the clinical and molecular spectrum of Lipoprotein Lipase (LPL) deficiency and to highlight the effect of a cost-effective indigenous diet for management of this disorder.This is a single-centre retrospective study. Fifteen patients from 14 kindreds with severe hypertriglyceridemia (more than 1000 mg/dl) were evaluated for a period of 12.5 y
Shwetha Kuthiroly +6 more
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Lipoprotein lipase and hepatic lipase
Current Opinion in Lipidology, 1990Lipoprotein metabolism involves two major steps (Eisenberg 1990). First, triglyceride (TG) rich lipoproteins bind transiently to lipoprotein lipase (LPL) at the vascular endothelium (Fig. 1). The enzyme rapidly hydrolyzes triglycerides, which accomplishes two things (Eckel 1989): it enables the tissues to utilize fatty acids from the lipoproteins, and ...
Thomas Olivecrona +1 more
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Lipoproteins and Lipoprotein Lipase
Comprehensive Physiology, 1985Abstract The sections in this article are: History Lipoproteins Chylomicrons Very‐Low‐Density Lipoproteins
Margit Hamosh, Paul Hamosh
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Lipoprotein Lipase and Atherosclerosis
Current Vascular Pharmacology, 2003Lipoprotein lipase (LPL) is a rate-limiting enzyme that hydrolyzes circulating triglyceride-rich lipoprotein such as very low density lipoproteins and chylomicrons. A decrease in LPL activity is associated with an increase in plasma triglycerides (TG) and decrease in high density lipoprotein (HDL) cholesterol.
Y, Stein, O, Stein
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β-lipoprotein, lipoprotein lipase and atromid
Journal of Atherosclerosis Research, 1963Summary The lipoprotein lipase activity eluted in connection with chromatographically separated β-lipoprotein was considerably lower in 6 cases of essential hyperlipaemia than the average for 7 healthy controls. Atromid administration seemed to increase the lipoprotein lipase activity per mg β-lipoprotein protein in 4 of 5 cases.
B, HOOD, P, BEDDING, B, CARLANDER
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Atherosclerosis, 1975
Rat heart lipoprotein lipase was highly purified by affinity chromatography using heparin-Sepharose 4B. When extracts of acetone powder were applied to columns, lipase activity was firmly bound to the gel matrix and was later eluted with 1.5 M NaCl. At this stage the eluted enzyme was purified 1500-fold.
J S, Twu, A S, Garfinkel, M C, Schotz
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Rat heart lipoprotein lipase was highly purified by affinity chromatography using heparin-Sepharose 4B. When extracts of acetone powder were applied to columns, lipase activity was firmly bound to the gel matrix and was later eluted with 1.5 M NaCl. At this stage the eluted enzyme was purified 1500-fold.
J S, Twu, A S, Garfinkel, M C, Schotz
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Lipoprotein lipase and atherosclerosis
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2015Lipoprotein lipase has long been known to hydrolyse triglycerides from triglycerides-rich lipoproteins. More recently, it has been shown to promote the binding of lipoproteins to various lipoprotein receptors. Evidence is also presented regarding the possible atherogenic role of lipoprotein lipase.
Junji, Kobayashi, Hiroshi, Mabuchi
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Primary Lipoprotein Lipase Deficiency
1986The enzyme lipoprotein lipase plays a central role in the processing of energy in the form of calorically dense triglyceride. Classical LPL deficiency usually presents in childhood with the multiple manifestations related to chylomicronemia. Many patients with genetic variations have been noted who differ in one of many ways from the classical patients.
J D, Brunzell +6 more
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Nihon rinsho. Japanese journal of clinical medicine, 1995
We describe molecular and physiological properties of human lipoprotein lipase (LPL) based on recent advanced knowledges. Human LPL is a lipolytic glycoprotein enzyme synthesized by extrahepatic tissues, mainly adipocytes, and its gene is located on chromosome 8p22 with 10 exons that encode mRNAs of 3.4 kb and 3.8 kb.
Y, Ikeda, A, Takagi, A, Yamamoto
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We describe molecular and physiological properties of human lipoprotein lipase (LPL) based on recent advanced knowledges. Human LPL is a lipolytic glycoprotein enzyme synthesized by extrahepatic tissues, mainly adipocytes, and its gene is located on chromosome 8p22 with 10 exons that encode mRNAs of 3.4 kb and 3.8 kb.
Y, Ikeda, A, Takagi, A, Yamamoto
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Lipoprotein lipase in diabetes
Diabetes/Metabolism Reviews, 1987Lipoprotein lipase has a central role in the metabolism of both triglyceride-rich particles and high density lipoproteins, and it is one determinant of both serum triglyceride and HDL concentrations. In man the enzyme activity in both adipose tissue and skeletal muscle is insulin dependent, and therefore it varies in diabetes according to ambient ...
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