Results 1 to 10 of about 453,084 (141)

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society

European Heart Journal, 2021
Recent advances in human genetics, together with a large body of epidemiologic, preclinical, and clinical trial results, provide strong support for a causal association between triglycerides (TG), TG-rich lipoproteins (TRL), and TRL remnants, and ...
H. Ginsberg, C. Packard, M. Chapman, J. Borén, C. Aguilar-Salinas, M. Averna, B. Ference, D. Gaudet, R. Hegele, S. Kersten, G. Lewis, A. Lichtenstein, P. Moulin, B. Nordestgaard, A. Remaley, B. Staels, E. Stroes, M. Taskinen, L. Tokgözoğlu, A. Tybjaerg-hansen, Jane K. Stock, A. Catapano   +21 more
semanticscholar   +1 more source

Relationship between lipoproteins, thrombosis, and atrial fibrillation

Cardiovascular Research, 2021
The prothrombotic state in atrial fibrillation (AF) occurs as a result of multifaceted interactions, known as Virchow’s triad of hypercoagulability, structural abnormalities, and blood stasis.
W. Ding, M. Protty, I. Davies, G. Lip
semanticscholar   +1 more source

MicroRNAs are Transported in Plasma and Delivered to Recipient Cells by High-Density Lipoproteins

Nature Cell Biology, 2011
Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and delivers them to recipient cells with functional ...
K. Vickers, Brian T. Palmisano, Bassem M. Shoucri, R. Shamburek, A. Remaley   +4 more
semanticscholar   +1 more source

Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins

Cellular and Molecular Life Sciences, 2018
The isolation of extracellular vesicles (EVs) from blood is of great importance to understand the biological role of circulating EVs and to develop EVs as biomarkers of disease.
N. Karimi, Aleksander Cvjetkovic, S. Jang, Rossella Crescitelli, M. H. Hosseinpour Feizi, R. Nieuwland, J. Lötvall, Cecilia Lässer   +7 more
semanticscholar   +1 more source

Effects of aerobic exercise on lipids and lipoproteins

Lipids in Health and Disease, 2017
Dyslipidemia is the risk of cardiovascular disease, and their relationship is clear. Lowering serum cholesterol can reduce the risk of coronary heart disease. At present, the main treatment is taking medicine, however, drug treatment has its limitations.
Ya-ting Wang, Danyan Xu
semanticscholar   +1 more source

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

European Heart Journal, 2011
Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically appraise evidence for elevated levels of triglyceride-rich lipoproteins (
M. Chapman, H. Ginsberg, P. Amarenco, F. Andreotti, J. Borén, A. Catapano, O. Descamps, E. Fisher, P. Kovanen, J. Kuivenhoven, P. Lesnik, L. Masana, B. Nordestgaard, K. Ray, Ž. Reiner, M. Taskinen, L. Tokgözoğlu, A. Tybjærg-Hansen, G. Watts   +18 more
semanticscholar   +1 more source

Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease

Vascular Health and Risk Management, 2016
Approximately 25% of US adults are estimated to have hypertriglyceridemia (triglyceride [TG] level ≥150 mg/dL [≥1.7 mmol/L]). Elevated TG levels are associated with increased cardiovascular disease (CVD) risk, and severe hypertriglyceridemia (TG levels ...
P. Toth
semanticscholar   +1 more source

Metabolism and Modification of Apolipoprotein B-Containing Lipoproteins Involved in Dyslipidemia and Atherosclerosis.

Biological and Pharmaceutical Bulletin, 2016
Increased levels of apolipoprotein B (apoB)-containing lipoproteins, such as low density lipoproteins (LDL) and chylomicron remnants, are associated with the development of atherosclerosis.
Shin-ya Morita
semanticscholar   +1 more source

Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease.

Arteriosclerosis, 1990
Several epidemiological studies have reported that the regional distribution of body fat is a significant and independent risk factor for cardiovascular disease (CVD) and related mortality.
J. Despres, S. Moorjani, P. Lupien, A. Tremblay, A. Nadeau, C. Bouchard   +5 more
semanticscholar   +1 more source

Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles [PDF]

, 2021
Boyan Zhang, Folkert Kuipers, Jan Freark de Boer, Jan Albert Kuivenhoven   +3 more
openalex   +1 more source