The Current Status of Research on High-Density Lipoproteins (HDL): A Paradigm Shift from HDL Quantity to HDL Quality and HDL Functionality. [PDF]
Int J Mol Sci, 2022 The quantity of high-density lipoproteins (HDL) is represented as the serum HDL-C concentration (mg/dL), while the HDL quality manifests as the diverse features of protein and lipid content, extent of oxidation, and extent of glycation.
Cho KH.
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The pleiotropic vasoprotective functions of high density lipoproteins (HDL). [PDF]
J Biomed Res, 2017 The pleiotropic functions of circulating high density lipoprotein (HDL) on peripheral vascular health are well established. HDL plays a pivotal role in reverse cholesterol transport and is also known to suppress inflammation, endothelial activation and ...
Boyce G, Button E, Soo S, Wellington C.
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Native High-Density Lipoproteins (HDL) with Higher Paraoxonase Exerts a Potent Antiviral Effect against SARS-CoV-2 (COVID-19), While Glycated HDL Lost the Antiviral Activity. [PDF]
Antioxidants (Basel), 2021 Human high-density lipoproteins (HDL) show a broad spectrum of antiviral activity in terms of anti-infection. Although many reports have pointed out a correlation between a lower serum HDL-C and a higher risk of COVID-19 infection and progression, the in
Cho KH, Kim JR, Lee IC, Kwon HJ.
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Loss of sphingosine 1-phosphate (S1P) in septic shock is predominantly caused by decreased levels of high-density lipoproteins (HDL). [PDF]
J Intensive Care, 2019 BackgroundSphingosine 1-phosphate (S1P) is a signaling lipid essential in regulating processes involved in sepsis pathophysiology, including endothelial permeability and vascular tone. Serum S1P is progressively reduced in sepsis patients with increasing
Winkler MS +6 more
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Microencapsulated Pomegranate Modifies the Composition and Function of High-Density Lipoproteins (HDL) in New Zealand Rabbits [PDF]
Molecules, 2020 Previous studies demonstrated that pomegranate, which is a source of several bioactive molecules, induces modifications of high-density lipoproteins (HDL) lipid composition and functionality.
Alan Dorantes-Morales +9 more
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Nonlinear dynamics of early atherosclerotic plaque formation may determine the efficacy of high density lipoproteins (HDL) in plaque regression. [PDF]
PLoS One, 2017 We use a computational model to explore the effect of foam cell accumulation on plaque regression following an increase in high density lipoprotein (HDL) influx into the plaque.
Chalmers AD, Bursill CA, Myerscough MR.
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Suppression of Endothelial Cell Apoptosis by High Density Lipoproteins (HDL) and HDL-associated Lysosphingolipids* [PDF]
Journal of Biological Chemistry, 2001 Apoptotic cell death following injury of vascular endothelium is assumed to play an important role in the pathogenesis of atherosclerosis. In this report, we demonstrate that high density lipoproteins (HDL), a major anti-atherogenic lipoprotein fraction,
J. Nofer +7 more
semanticscholar +4 more sources
Adsorption of high density lipoproteins (HDL) on solid surfaces [PDF]
Journal of Colloid and Interface Science, 1996 The adsorption of high density lipoproteins (HDL) on polyethylene (PE), poly(2-hydroxyethyl methacrylate) (poly(HEMA)), polyesterurethane (PU), Biomer, and mica surfaces was studied.
M. Feng +7 more
semanticscholar +4 more sources
Relationship of the low-density lipoprotein (LDL)/high-density lipoprotein (HDL) index with antioxidant enzymes and with the oxLDL/HDL index [PDF]
Gaceta Médica de México, 2023 The low-density lipoprotein (LDL)/high-density lipoprotein (HDL) index is a predictive factor for atherosclerosis, which is associated with oxidative modifications.To assess the association of the index with oxidative stress markers.444 subjects were included and were clinically, anthropometrically and biochemically characterized; superoxide dismutase,
Eduardo Monjaraz-Guzmán +8 more
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Effects of superoxide anion attack on the lipoprotein HDL
Molecular and Cellular Biochemistry, 2022 AbstractHigh-density lipoprotein (HDL) is an anti-atherosclerotic lipoprotein. Thanks to the activity of apolipoprotein ApoA1, the principal protein component of HDL, this last is responsible for converting cholesterol into ester form and transporting excessive cholesterol to the liver (“reverse cholesterol transport” RCT). When HDL undergoes oxidation,
Napolitano G. +5 more
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