Results 101 to 110 of about 451,388 (320)

Effect of a neutralizing monoclonal antibody to cholesteryl ester transfer protein on the redistribution of apolipoproteins A-IV and E among human lipoproteins.

Journal of Lipid Research, 1989
The effect of inhibiting cholesteryl ester transfer protein (CETP) on the in vitro redistribution of apolipoproteins(apo) A-IV and apoE among lipoproteins in whole plasma was studied in seven normal male subjects.
C L Bisgaier, M V Siebenkas, C B Hesler, T L Swenson, C B Blum, Y L Marcel, R W Milne, R M Glickman, A R Tall   +8 more
doaj   +1 more source

Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]

, 2018
The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A, Currier, Judith S, Danoff, Ann, Kelesidis, Theodoros, Kendall, Michelle A, Schmidt, Ann Marie   +5 more
core   +1 more source

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport

Nature Communications, 2017
Brown and beige adipocytes combust nutrients for thermogenesis and through their metabolic activity decrease pro-atherogenic remnant lipoproteins in hyperlipidemic mice. However, whether the activation of thermogenic adipocytes affects the metabolism and
A. Bartelt, A. Bartelt, C. John, Nicola Schaltenberg, J. Berbée, A. Worthmann, M. L. Cherradi, C. Schlein, Julia Piepenburg, M. Boon, F. Rinninger, M. Heine, K. Toedter, A. Niemeier, S. K. Nilsson, S. K. Nilsson, Markus Fischer, S. Wijers, W. Lichtenbelt, L. Scheja, P. Rensen, J. Heeren   +21 more
semanticscholar   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Regulation of lipid transfer between lipoproteins by an endogenous plasma protein: selective inhibition among lipoprotein classes.

Journal of Lipid Research, 1994
Lipid transfer protein (LTP) remodels plasma lipoproteins by promoting mass transfers of cholesteryl ester (CE) and triglyceride between lipoproteins.
R E Morton, D J Greene
doaj   +1 more source

The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis? [PDF]

Journal of Lipid Research, 2010
There is unequivocal evidence of an inverse association between plasma high-density lipoprotein (HDL) cholesterol concentrations and the risk of cardiovascular disease, a finding that has led to the hypothesis that HDL protects from atherosclerosis. This review details the experimental evidence for this "HDL hypothesis".
Vergeer, Menno, Holleboom, Adriaan G, Kastelein, John J P, Kuivenhoven, Jan Albert   +3 more
openaire   +4 more sources

High-density lipoprotein (HDL) particle size and concentration changes in septic shock patients

Annals of Intensive Care, 2019
BackgroundSepsis is associated with systemic inflammation that may impact lipoprotein function. In particular, high-density lipoproteins (HDLs) that display pleiotropic protective roles may be dysfunctional in septic conditions. The aim of this study was
Sébastien Tanaka, Dévy Diallo, S. Delbosc, C. Genève, N. Zappella, Jennyfer Yong-Sang, Jessica Patché, A. Harrois, S. Hamada, E. Denamur, P. Montravers, J. Duranteau, O. Meilhac   +12 more
semanticscholar   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source