Molecular simulation of discoidal HDL lipoprotein particles [PDF]
, 2023 High-density lipoprotein (HDL) has been determined to play an essential role as an atheroprotective in atherosclerosis – the thickening and hardening of arteries. HDL particles are important delivery vehicles in the reverse cholesterol transport (RCT) pathway wherein excess cholesterol is removed from peripheral tissues and transported to the liver for
Siddiq, Hind, Anwar, Jamshed
openaire
Protein and cell therapy for lecithin-cholesterol acyltransferase (LCAT) deficiency [PDF]
, 2009 Lecithin-cholesterol acyltransferase (LCAT) is an enzyme principally secreted by the liver into the circulation where it esterifies cholesterol and plays a key role in high- density lipoprotein (HDL) metabolism. In familial and acquired (liver disease)
Low, J K, Low, J.K.
core
ESC Heart Failure, Volume 12, Issue 2, Page 1141-1150, April 2025.Abstract Background Arterial stiffness is a crucial factor in determining an increase in systolic blood pressure and pulse pressure and can also predict the development of cardiovascular disease (CVD). The purpose of this study was to examine the relationship between arterial stiffness and future CVD.
Susan Darroudi +10 more
wiley +1 more source
Journal of Lipid Research, 1989 Electron microscopic studies of perfused rat adrenals indicate that plasma lipoproteins become concentrated in a specialized cell surface compartment called microvillar channels.
E Reaven, M Spicher, S Azhar
doaj +1 more source
Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice [PDF]
, 2005 Plasma apolipoprotein E (apoE) is a 34-kDa polymorphic protein which has atheroprotective actions by clearing remnant lipoproteins and sequestering excess cellular cholesterol.
Dickson, G +7 more
core
Infusional high-density lipoproteins therapies as a novel strategy for treating atherosclerosis
, 2016 High-density lipoproteins (HDL) have received considerable interest as a target for the development of novel anti-atherosclerotic agents beyond conventional approaches to lipid lowering.
Stephen J. Nicholls +3 more
core +1 more source
Biophysical characterization of reactions associated with reverse cholesterol transport [PDF]
, 2012 This thesis aimed at improving our understanding of reactions relevant in the reverse cholesterol transport (RCT). RCT facilitates cholesterol homeostasis and is the most important pathway involved in cardiovascular disease.
Zehender, Fabian
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1464-1468, April 2025.Abstract Background There are limited data on the efficacy of smartphone‐based personal health records (PHRs) in patients with cardiovascular disease. This study aimed to examine the processes, outcomes and challenges associated with the implementation of integrated PHRs in patients with heart failure (HF) or coronary artery disease (CAD). Methods This
Kotaro Nochioka +16 more
wiley +1 more source
Acute inhibition of hepatic lipase and increase in plasma lipoproteins after alcohol intake.
Journal of Lipid Research, 1984 Chronic alcohol intake is associated with an increase in fasting plasma high density lipoproteins (HDL). To study alcohol's acute effects on plasma lipoproteins, we measured plasma lipoprotein concentrations and activities of postheparin plasma lipases ...
C S Goldberg, A R Tall, S Krumholz
doaj +1 more source
Native High-Density Lipoproteins (HDL) with Higher Paraoxonase Exerts a Potent Antiviral Effect against SARS-CoV-2 (COVID-19), While Glycated HDL Lost the Antiviral Activity. [PDF]
Antioxidants (Basel), 2021 Cho KH, Kim JR, Lee IC, Kwon HJ.
europepmc +1 more source