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High-density lipoproteins (HDL) composition and function in preeclampsia

Archives of Gynecology and Obstetrics, 2018
To evaluate (a) the properties of high-density lipoproteins (HDL)/cholesterol, which include apolipoprotein A-1 (ApoA1) and paraoxonase1 (PON1), both are negative predictors of cardiovascular risk and (b) HDL function, among women with preeclampsia (PE).
Yael Einbinder   +8 more
openaire   +3 more sources

High-density Lipoprotein (HDL) Dysfunction and the Future of HDL

Current Vascular Pharmacology, 2018
Although High Density Lipoprotein Cholesterol (HDL-C) levels are inversely proportional to cardiovascular risk in many studies, recent pharmacological interventional studies with HDL-C raising strategies did not show a benefit in terms of vascular events. The HDL particle is heterogenous with anti-atherogenic functions and non-vascular effects.
S. Ertek
openaire   +3 more sources

Lipoproteins, HDL/LDL

2004
Fayanne E. Thorngate, David L. Williams
openaire   +2 more sources

Paraoxonase Genotypes, Lipoprotein Lipase Activity, and HDL

Arteriosclerosis, Thrombosis, and Vascular Biology, 1996
Paraoxonase, an enzyme associated with the high density lipoprotein (HDL) particle, hydrolyzes paraoxon, the active metabolite of the insecticide parathion. Several studies have shown that paraoxonase levels in humans have a distribution characteristic of two alleles, one with low activity and the other with high activity.
D N, Nevin   +6 more
openaire   +2 more sources

Studies on Human Serum High-Density Lipoproteins (HDL) IV. Isolation of Lipoprotein Families after Incubation of HDL

Scandinavian Journal of Clinical & Laboratory Investigation, 1975
The high-density lipoproteins (HDL) of human serum appear to be unstable and easily exposed to chemical changes during isolation. In earlier studies we have isolated and purified HDL subfractions either in the presence of an SH-blocking agent, DTNB, or in the cold.
S O, Olofsson, A, Gustafson, U, Svanberg
openaire   +2 more sources

Low‐Density Lipoproteins, High‐Density Lipoproteins (HDL), and HDL‐Associated Proteins Differentially Modulate Chronic Myelogenous Leukemia Cell Viability

Lipids, 2020
AbstractCellular lipid metabolism, lipoprotein interactions, and liver X receptor (LXR) activation have been implicated in the pathophysiology and treatment of cancer, although findings vary across cancer models and by lipoprotein profiles. In this study, we investigated the effects of human‐derived low‐density lipoproteins (LDL), high‐density ...
Catherine J. Andersen   +6 more
openaire   +2 more sources

The interaction of lipolysis products of very low density lipoprotein with plasma high density lipoprotein (HDL): perfusate HDL with plasma HDL subfractions

Biochemistry and Cell Biology, 1987
The nature of the interaction of high density lipoproteins (HDL), formed during lipolysis of human very low density lipoprotein (VLDL) by perfused rat heart, with subfractions of human plasma HDL was investigated. Perfusate HDL, containing apoliproproteins (apo) E, C-II, and C-III but no apo A-I or A-II, was incubated with a subfraction of HDL (HDL-A)
S P, Tam, W C, Breckenridge
openaire   +2 more sources

Metabolismus und Funktion der Lipoproteine hoher Dichte (HDL)

Praxis, 2019
Zusammenfassung. HDL wurde lange Zeit als das «gute Cholesterin» angesehen, das für die Gesundheit des Gesamtorganismus und speziell des kardiovaskulären Systems essenziell ist. HDL ist jedoch komplex aufgebaut und durchläuft dynamische Umbauprozesse, an dem zahlreiche Komponenten, Enzyme und verschiedene Gewebe beteiligt sind.
Jomard, Anne, Osto, Elena
openaire   +1 more source

Degradation of High-Density Lipoproteins (HDL) In Vitro

Scandinavian Journal of Clinical and Laboratory Investigation, 1974
An isolation procedure is described in which, in the presence of a SH-blocking agent, DTNB, LP-B, and albumin-free HDL2 and HDL3 were isolated. Subfractionation on hydroxylapatite column chromatography of HDL2 and HDL3 respectively, gave three parent fractions of characteristic polypeptide composition.
S O, Olofsson, A, Gustafson
openaire   +2 more sources

High Density Lipoprotein (HDL) Metabolism in Noninsulin-Dependent Diabetes Mellitus: Measurement of HDL Turnover Using Tritiated HDL*

The Journal of Clinical Endocrinology & Metabolism, 1987
High density lipoprotein (HDL) kinetics were studied by injecting [3H]apoprotein A-I (apoA-I)/HDL into 12 subjects with normal glucose tolerance and 12 patients with noninsulin-dependent diabetes mellitus (NIDDM). The results indicate that the mean fractional catabolic rate (FCR) of apoA-I/HDL was significantly faster [0.63 +/- 0.07 (+/- SEM) vs. 0.39 +
A, Golay   +5 more
openaire   +2 more sources

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