Results 51 to 60 of about 387,913 (205)

Structure-function relationships of HDL in diabetes and coronary heart disease.

JCI Insight, 2019
High-density lipoproteins (HDL) contain hundreds of lipid species and proteins and exert many potentially vasoprotective and anti-diabetogenic activities on cells.
M. Cardner, M. Yalcinkaya, S. Goetze, E. Luca, Miroslav Balaz, M. Hunjadi, J. Hartung, A. Shemet, N. Kraenkel, Silvija Radosavljevic, M. Keel, A. Othman, G. Karsai, T. Hornemann, M. Claassen, G. Liebisch, E. Carreira, A. Ritsch, U. Landmesser, J. Krützfeldt, C. Wolfrum, B. Wollscheid, N. Beerenwinkel, L. Rohrer, A. von Eckardstein   +24 more
semanticscholar   +1 more source

Biophysical characterization of the interaction of high‐density lipoprotein (HDL) with endotoxins [PDF]

European Journal of Biochemistry, 2002
The interaction of bacterial endotoxins [lipopolysaccharide (LPS) and the ‘endotoxic principle’ lipid A], with high‐density lipoprotein (HDL) from serum was investigated with a variety of physical techniques and biological assays. HDL exhibited an increase in the gel to liquid crystalline phase transition temperature Tc and a rigidification of the acyl
Brandenburg, Klaus, Jürgens, Gudrun, Andrä, Jörg, Lindner, Buko, Koch, Michel H. J., Blume, Alfred, Garidel, Patrick   +6 more
openaire   +4 more sources

High density lipoprotein-induced cardiac prostacyclin synthesis in vitro: relationship to cardiac arachidonate mobilization.

Journal of Lipid Research, 1988
The objectives of this study were to characterize the effects of plasma lipoproteins on prostacyclin (PGI2) production by the Langendorff-perfused rabbit heart, and to determine the mechanism of lipoprotein-induced cardiac PGI2 production.
W A Van Sickle, H G Wilcox, K U Malik, A Nasjletti   +3 more
doaj  

Oxysterols in Vascular Cells and Role in Atherosclerosis [PDF]

Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.213-229, 2024, Advances in Experimental Medicine and Biology
Atherosclerosis is a major cardiovascular complication of diseases associated with elevated oxidative stress such as type 2 diabetes and metabolic syndrome. In these situations, low density lipoproteins (LDL) undergo oxidation. Oxidized LDL display proatherogenic activities through multiple and complex mechanisms which lead to dysfunctions of vascular ...
arxiv   +1 more source

The Effect of Chia Seeds on High-Density Lipoprotein (HDL) Cholesterol

Cureus, 2023
Chia seeds are touted as a healthy food capable of providing a beneficial effect on high-density lipoprotein (HDL) cholesterol. Similar claims have been made for oats in various forms, claiming that they improve cholesterol or are in some way "heart healthy." This study aims to demonstrate the effect of daily consumption of chia seeds, if any, on HDL ...
Dickens, Brian, Sassanpour, Mana, Bischoff, Evan L   +2 more
openaire   +2 more sources

Isolation and characterization of human apolipoprotein M-containing lipoproteins

Journal of Lipid Research, 2006
Apolipoprotein M (apoM) is a novel apolipoprotein with unknown function. In this study, we established a method for isolating apoM-containing lipoproteins and studied their composition and the effect of apoM on HDL function.
Christina Christoffersen, Lars Bo Nielsen, Olof Axler, Astra Andersson, Anders H. Johnsen, Bjoärn Dahlbaäck   +5 more
doaj  

Artificial High Density Lipoprotein Nanoparticles in Cardiovascular Research

Molecules, 2019
Lipoproteins are endogenous nanoparticles which are the major transporter of fats and cholesterol in the human body. They play a key role in the regulatory mechanisms of cardiovascular events.
Karin Kornmueller, Ivan Vidakovic, Ruth Prassl   +2 more
doaj   +1 more source

The biological activity of high-density lipoprotein fractions and their role in the development of cardiovascular diseases [PDF]

Терапевтический архив, 2016
Increasing the human plasma concentration of high-density lipoproteins (HDL) may be part of strategy for control of cardiovascular diseases (CVD). HDL particles vary in their structure, metabolism, and biological activity.
Ya D Babintseva, L Camont, J Chapman, M Lhomme, V P Karagodin, A Kontush, A N Orekhov   +6 more
doaj   +1 more source

HDL cholesterol: reappraisal of its clinical relevance

Clinical Research in Cardiology, 2017
BackgroundWhile several lines of evidence prove that elevated concentrations of low-density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its clinical consequences, high-density lipoproteins are still widely believed to
W. März, M. Kleber, H. Scharnagl, T. Speer, S. Zewinger, A. Ritsch, K. Parhofer, A. von Eckardstein, U. Landmesser, U. Laufs   +9 more
semanticscholar   +1 more source

Thematic review series: Patient-Oriented Research. What have we learned about HDL metabolism from kinetics studies in humans?

Journal of Lipid Research, 2006
Plasma measurements of lipids, lipoproteins, and apolipoproteins provide information on the static levels of these fractions without providing key information on the dynamic fluxes of lipoproteins in the circulation.
Shirya Rashid, Bruce W. Patterson, Gary F. Lewis   +2 more
doaj