Results 131 to 140 of about 66,086 (315)

Avaliação do polimorfismo genético e atividade da enzina paroxonase em pacientes hipercolesterolêmicos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2004.A aterosclerose é a principal causa de morbidade e mortalidade no mundo ocidental e envolve ...
Favarin, Maria Elisa
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Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Estudo de uma fração rica em compostos fenólicos provenientes de uvas da variedade bordô (Vitis labrusca L.), sobre o sistema cardiovascular: enfoque na aterosclerose experimental [PDF]

, 2005
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaO objetivo geral deste estudo foi investigar a atividade de uma fração rica em compostos fenólicos - Fração Acetato de ...
Schuldt, Elke Zuleika
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Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Genetic variation at the apolipoprotein B gene and associations with coronary heart disease and its factors.

, 1996
PhDCoronary heart disease (CED) is the major cause of mortality in Western societies. The main risk factors are plasma lipoprotein concentrations, smoking, blood pressure and family history.
Rajput-Williams, Jayshri
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Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Effects of native and modified low density lipoproteins on functional and biochemical aspects of cells involved in the thrombotic process

, 1993
Recent studies indicate that low density lipoproteins (LDL), either native and/or chemically and/ or cell modified LDL, interact with blood and vascular cells influencing specific functional and biochemical aspects that are of relevance in the onset of ...
L. Sironi, C. Banfi, S. Colli, S. Eligini, L. Mannucci, L. Mussoni, M. Camera, P. Maderna, M. Sirtori, F. Pazzucconi, L. Prati, D. Baldassarre, E. Tremoli   +12 more
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Tissue-factor pathway inhibitor and lipoproteins. Evidence for association with and regulation by LDL in human plasma.

, 1994
Tissue-factor pathway inhibitor (TFPI) is a potent inhibitor of extrinsic coagulation, which is mainly associated with lipoproteins in circulating blood. Gel filtration of human plasma confirmed the presence of three peaks in which approximately 10%, 70%,
P M Sandset, B Svensson, N E Huseby, V Lyngmo, A Nordøy, J B Hansen   +5 more
core   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

Liver cells and lipoproteins [PDF]

, 1984
The liver plays a central regulatory role in ·the metabolism of sugars, proteins and lipids. In contrast with sugars, lipids have to be complexed with proteins to socalled lipoproteins before they can be transported in the blood.
Nagelkerke, J.F. (Jan Frederik)
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