Results 161 to 170 of about 106,428 (294)

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

open access: yesESC Heart Failure, EarlyView.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna   +4 more
wiley   +1 more source

Interaction of free cholesterol and apoproteins of low and high density lipoproteins with isolated rabbit hepatocytes.

open access: yesJournal of Lipid Research, 1981
Primary cultures of rabbit hepatocytes were incubated with rabbit high density (HDL) and low density (LDL) lipoproteins in order to compare the surface transfer of free cholesterol with the uptake of apoproteins.
J P O'Malley, P A Soltys, O W Portman
doaj  

BUN‐to‐ALB ratio as an effective predictor of 30 day mortality in ADHF patients in eastern China

open access: yesESC Heart Failure, EarlyView.
Abstract Aims The blood urea nitrogen‐to‐albumin ratio (BAR) is considered a potential indicator for assessing the poor prognosis of heart failure (HF). However, its prognostic value for Chinese patients with acute decompensated HF (ADHF) remains unclear.
Xin Huang   +8 more
wiley   +1 more source

A novel explanation for the reduced LDL cholesterol in severe hypertriglyceridemia.

open access: yesJournal of Lipid Research, 1989
When [3H]cholesteryl ester-labeled low density (LDL) and intermediate density lipoproteins (IDL) from a normotriglyceridemic, hypercholesterolemic rabbit were injected into severely hypertriglyceridemic, hypercholesterolemic rabbits, 60% of the label ...
A Minnich   +2 more
doaj  

Exploring heart failure prevalence and dimensions: A comprehensive NT‐proBNP study in high‐risk primary care patients

open access: yesESC Heart Failure, EarlyView.
The diagnostic pathway of high‐risk primary care patients through NT‐proBNP. Abstract Introduction Early detection of heart failure (HF), particularly in asymptomatic individuals, is essential for timely intervention. This study aimed to determine the prevalence of HF among high‐risk individuals in primary care using N‐terminal probrain natriuretic ...
Ahmet Celik   +17 more
wiley   +1 more source

Interaction of serum lipoproteins with the intestine. Evidence for specific high density lipoprotein-binding sites on isolated rat intestinal mucosal cells

open access: yesJournal of Lipid Research, 1983
To determine if plasma lipoproteins interact and therefore possibly regulate intestinal lipoprotein metabolism, we investigated the binding, internalization, and degradation of 125I-labeled low density lipoprotein (LDL) and high density lipoprotein (HDL)
N Suzuki, N Fidge, P Nestel, J Yin
doaj  

Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in patients with ...
Zhuoshan Huang   +18 more
wiley   +1 more source

Role of lipid peroxidation in the inhibition of mononuclear cell proliferation by normal lipoproteins

open access: yesJournal of Lipid Research, 1991
Stimulated peripheral blood mononuclear cells (PBMC) can oxidize normal lipoproteins, and sufficiently oxidized lipoproteins are cytotoxic. However, the role of lipid peroxidation in the inhibition of mitogen-stimulated PBMC proliferation by physiologic ...
BL Kasiske, WF Keane
doaj  

Prognostic value of lipid parameters among patients with heart failure: A systematic review and meta‐analysis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims We sought to evaluate the prognostic value of different lipid parameters in patients with heart failure (HF). Methods and Results Electronic databases including MEDLINE, Embase, CENTRAL, and Web of Science were searched to identify studies that reported the association of any of the four lipid parameters [total cholesterol (TC), high ...
Ahmed Sayed   +9 more
wiley   +1 more source

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