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Genetic influences on macrophage function and lipid uptake in atherosclerosis. [PDF]
O'Callaghan CA, Jiang J.
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The mediating role of inflammation-related indicators in the association of remnant cholesterol with gestational diabetes mellitus. [PDF]
Lin L, Lin J, Yan J, Wang X.
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Clinical Laboratory, 2016
Oxidized low-density lipoprotein (ox-LDL) plays a principal role in diabetes complications, though ox-LDL concentrations and its functions are dependents of other oxidative and anti-oxidative particles. The oxLDL to low-density lipoprotein ratio (ox-LDL/LDL) and ox-LDL to high-density lipoprotein ratio (ox-LDL/HDL) as new lipid biomarkers may serve as ...
Mahtab Motamed+5 more
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Oxidized low-density lipoprotein (ox-LDL) plays a principal role in diabetes complications, though ox-LDL concentrations and its functions are dependents of other oxidative and anti-oxidative particles. The oxLDL to low-density lipoprotein ratio (ox-LDL/LDL) and ox-LDL to high-density lipoprotein ratio (ox-LDL/HDL) as new lipid biomarkers may serve as ...
Mahtab Motamed+5 more
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Circulating low density lipoprotein (LDL)
Hormone Molecular Biology and Clinical Investigation, 2018Abstract Low-density lipoprotein (LDL) particles are known as atherogenic agents in coronary artery diseases. They modify to other electronegative forms and may be the subject for improvement of inflammatory events in vessel subendothelial spaces. The circulating LDL value is associated with the plasma PCSK-9 level. They internalize into
Reza Hosseini-Fard+2 more
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Low density lipoprotein (LDL) binding affinity for the LDL receptor in hyperlipoproteinemia
Atherosclerosis, 1999We measured the binding affinity of low density lipoprotein (LDL) for the LDL receptor in patients with various types of hyperlipoproteinemia and investigated the effects of LDL lipid composition and particle size on receptor affinity. LDL (1.019 < d < 1.063) was isolated by sequential ultracentrifugation from the serum of normolipidemic controls and ...
Taku Yamamura+3 more
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Low-density lipoprotein (LDL) oxidizability before and after LDL apheresis
Metabolism, 1999Oxidation of low-density lipoprotein (LDL) plays a major role in the development of atherosclerosis. Hypercholesterolemia has been associated with enhanced in vitro oxidation of LDL, and lipid-lowering therapy reduces LDL oxidizability. In the present study, we investigated whether LDL apheresis performed with different techniques affects in vitro ...
Peter Schwandt+3 more
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LDL receptor-independent and -dependent uptake of lipoproteins
Atherosclerosis, 1995The liver plays a decisive role in the regulation of the plasma levels of atherogenic lipoproteins. The primary liver interaction site for chylomicron-remnants and VLDL remnants (beta-VLDL) is still unidentified, while the subsequent cellular uptake is likely to be mediated in concert by the LDL receptor related protein (LRP) and the LDL receptor.
C.J.M. Vogelezang+4 more
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The Role of the LDL Receptor in Lipoprotein Metabolism
1987The discovery of the LDL receptor in cultured mammalian cells by Goldstein and Brown in 1973 was followed by a rapid increase in our understanding of cellular and total body cholesterol metabolism1. The LDL receptor is the starting point for an intracellular pathway which is of fundamental importance in regulating cellular cholesterol metabolism ...
David W. Bilheimer, Scott M. Grundy
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The lipoproteins selections aphereses with LDL Lipopak 400
Transfusion and Apheresis Science, 2013The lipid lowering is one of the main ways to achieve reduction of the atherosclerosis progress. In the rare patients with homozygous familial hypercholesterolemia low density lipoprotein cholesterol apheresis should be performed as these patients usually have extremely high low density lipoprotein cholesterol concentrations and these patients usually ...
Aleksandras Laucevičius+4 more
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