Results 101 to 110 of about 285,687 (237)

ApoE-3-specific metabolism of human plasma very low density lipoproteins in cultured J-774 macrophages.

Journal of Lipid Research, 1990
The effect of apoprotein E on the cellular metabolism of very low density lipoproteins (VLDL) was studied using the J-774 macrophage-like cell line as a foam cell model.
E Granot, S Eisenberg
doaj  

The effect of lyophilised oral faecal microbial transplantation on functional outcomes in dogs with diabetes mellitus

Journal of Small Animal Practice, EarlyView.
Objectives We aimed to determine if oral faecal microbiota transplantation improves indices of glycaemic control, changes the faecal dysbiosis indices, alters faecal short‐chain fatty acid and bile acid profiles and increases serum glucagon‐like‐peptide 1 concentrations in diabetic dogs.
R. Brown, P. Barko, J. D. J. Ruiz Romero, D. A. Williams, A. Gochenauer, J. Nguyen‐Edquilang, J. S. Suchodolski, R. Pilla, H. Ganz, N. Lopez‐Villalobos, A. Gal   +10 more
wiley   +1 more source

Distribution of apolipoproteins A-I and B among intestinal lipoproteins.

Journal of Lipid Research, 1985
Chylomicrons and very low density lipoproteins (VLDL) are produced by the intestine and these nascent particles are thought to be similar to their counterparts in intestinal lymph.
D H Alpers, D R Lock, N Lancaster, K Poksay, G Schonfeld   +4 more
doaj  

Efficacy and Safety of Tirzepatide on Weight Loss in Patients Without Diabetes Mellitus: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Obesity Reviews, EarlyView.
ABSTRACT Tirzepatide has positive effects on weight loss in individuals with overweight or obesity. Considering its broad side‐effect profile, its efficacy and safety in individuals without diabetes mellitus (DM) are yet to be fully understood. To address this, we conducted a comprehensive meta‐analysis of six randomized trials on individuals with ...
Sharath Kommu, Param P. Sharma, Rachel M. Gabor   +2 more
wiley   +1 more source

Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway.

Journal of Lipid Research, 1996
Very low density lipoproteins (VLDL) are produced in the liver and contain apolipoprotein (apo) B-100 and endogenous lipids. By contrast, ingestion of fat leads to formation of chylomicrons containing apoB-48 secreted from the intestine. In this study, a
J Bjorkegren, C J Packard, A Hamsten, D Bedford, M Caslake, L Foster, J Shepherd, P Stewart, F Karpe   +8 more
doaj  

Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes

Experimental Physiology, EarlyView.
Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox, Aaron Raman, Timothy Fairchild, John P. Beilby, Bu B. Yeap, Jeremy K. Nicholson, Julien Wist, Jeremiah Peiffer, Nathan G. Lawler   +8 more
wiley   +1 more source

Hepatic metabolism and secretion of a cholesterol-enriched lipoprotein fraction.

Journal of Lipid Research, 1987
A potentially important source of cholesterol secreted in bile is cholesterol-rich lipoproteins. However, the fate of the cholesterol carried in these lipoproteins after hepatic uptake has not been investigated. We harvested an apoE- and cholesterol-rich
B G Stone, D Schreiber, L D Alleman, C Y Ho   +3 more
doaj  

Bioactive Compounds, Their Mechanisms of Action, and Cardioprotective Effects of Pomegranate (Punica granatum): A Comprehensive Review

eFood, Volume 6, Issue 4, August 2025.
Pomegranate parts (arils, peel, and flower) contain antioxidants, polyphenols, and flavonoids. These bioactives reduce inflammation, improve endothelial function, and modulate lipids. Regular intake lowers blood pressure, LDL, and atherosclerotic plaque while increasing HDL.
Esha Saeed, Farah Javed, Zoya Rana, Rashida Perveen, Iftikhar Younis Mallhi, Izza Amjad, Quratulain Maqsood, Nauman Ali Chaudhary, Saleha Binte Tahir, Arooj Fatima, Noor Fatima Rasheed, Esther Ugo Alum   +11 more
wiley   +1 more source

The role of different albumin preparations on production of human plasma lipoprotein-like particles in vitro

Journal of Lipid Research, 1980
Because we found apoprotein contamination of some high-grade commercial albumins, we studied this effect on formation of lipoprotein-like particles during lipolysis of human very low density lipoprotein (VLDL) in vitro.
R J Deckelbaum, T Olivecrona, M Fainaru
doaj  

Role for the liver X receptor agonist 22‐ketositosterol in preventing disease progression in an Alzheimer's disease mouse model

British Journal of Pharmacology, Volume 182, Issue 16, Page 3744-3766, August 2025.
Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens, Na Zhan, Sammie C. Yam, Marcella Palumbo, Lorenzo Pontini, Frank P. J. Leijten, Leonie van Vark‐van der Zee, Gardi Voortman, Silvia Friedrichs, Albert Gerding, Maura Marinozzi, Johan W. Jonker, Folkert Kuipers, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder   +15 more
wiley   +1 more source