Results 141 to 150 of about 284,504 (254)

Structured functional regression models for high-dimensional spatial spectroscopy data [PDF]

open access: yesarXiv, 2013
Modeling and analysis of spectroscopy data is an active area of research with applications to chemistry and biology. This paper focuses on analyzing Raman spectra obtained from a bone fracture healing experiment, although the functional regression model for predicting a scalar response from high-dimensional tensors can be applied to any spectroscopy ...
arxiv  

Defective lymphatic vasculature in obesity

open access: yesObesity Reviews, EarlyView.
Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley   +1 more source

The giant low-density lipoproteins (LDL) accumulation in the multi-layer artery wall model [PDF]

open access: yesarXiv, 2014
The mathematical, four-layer model of the LDL transport across the arterial wall including the sensitivity of the transport coefficients to the wall shear stress (WSS) is studied. In that model the advection-diffusion equations in porous media are used to determine the LDL concentration profiles in each layer of the arterial wall.
arxiv  

The ins and outs of liver fat metabolism: The effect of phenotype and diet on risk of intrahepatic triglyceride accumulation

open access: yesExperimental Physiology, EarlyView.
Abstract In health, the liver is a metabolically flexible organ that plays a key role in regulating systemic lipid and glucose concentrations. There is a constant flux of fatty acids (FAs) to the liver from multiple sources, including adipose tissue, dietary, endogenously synthesized from non‐lipid precursors, intrahepatic lipid droplets and recycling ...
Kieran Smith   +2 more
wiley   +1 more source

Secretion of lipids, apolipoproteins, and lipoproteins by human hepatoma cell line, HepG2: effects of oleic acid and insulin

open access: yesJournal of Lipid Research, 1987
The aim of this study was to determine the effect of oleic acid and insulin on the secretion of lipoproteins by HepG2 cells grown in minimum essential medium.
N Dashti, G Wolfbauer
doaj  

The Twin Cycle Hypothesis of type 2 diabetes aetiology: From concept to national NHS programme

open access: yesExperimental Physiology, EarlyView.
Abstract The development of magnetic resonance methods for quantifying intra‐organ metabolites has permitted advances in the understanding of fasting and post‐prandial carbohydrate and lipid handling in people with and without type 2 diabetes. Insulin resistance in the liver was shown to be related to excess intra‐organ fat and was able to be returned ...
Roy Taylor
wiley   +1 more source

Nascent lipoproteins from recirculating and nonrecirculating liver perfusions and from the hepatic Golgi apparatus of African green monkeys

open access: yesJournal of Lipid Research, 1987
Perfusate apoB-100-containing lipoproteins from the isolated, perfused livers of African green monkeys consist of significant amounts of d greater than 1.006 g/ml particles in addition to very low density lipoproteins (VLDL).
F L Johnson, L L Swift, L L Rudel
doaj  

Regression Discontinuity Designs: A Decision Theoretic Approach [PDF]

open access: yesarXiv, 2016
The regression discontinuity design (RDD) is a quasi-experimental design that can be used to identify and estimate the causal effect of a treatment using observational data. In an RDD, a pre-specified rule is used for treatment assignment, whereby a subject is assigned to the treatment (control) group whenever their observed value of a specific ...
arxiv  

Functional sympatholysis of neuropeptide Y‐mediated vasoconstriction in humans

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Neuropeptide Y (NPY) is a neurotransmitter that elicits potent vasoconstriction and is co‐released with noradrenaline during sympathoexcitation, as occurs during exercise. We assessed whether NPY‐mediated vasoconstriction is blunted during exercise (i.e.
Denis J. Wakeham   +6 more
wiley   +1 more source

Metabolism of apoB-100 in lipoproteins separated by density gradient ultracentrifugation in normal and Watanabe heritable hyperlipidemic rabbits.

open access: yesJournal of Lipid Research, 1990
We have examined the capability of a previously developed compartmental model to explain the kinetics of radioiodinated apolipoprotein (apo) B-100 in very low density lipoproteins (VLDL), intermediate density lipoproteins (IDL), and low density ...
DM Shames, N Yamada, RJ Havel
doaj  

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