Results 161 to 170 of about 284,504 (254)

Carotid Plaque‐Derived Small Extracellular Vesicles Mediate Atherosclerosis and Correlate With Plaque Vulnerability

MedComm, Volume 6, Issue 6, June 2025.
We profiled the differences in miRNA expression of plaque‐derived small extracellular vesicles (psEVs) from stable and vulnerable plaques of patients with asymptomatic carotid artery stenosis (aCAS), and identified five plasma‐derived sEV miRNAs as potential biomarkers for diagnosing plaque vulnerability.
Xin Xu, Taoyuan Lu, Yao Feng, Wenbo Cao, Dianwei Liu, Peng Gao, Yan Ma, Yabing Wang, Bin Yang, Yanfei Chen, Jian Chen, Ran Xu, Xinyu Wang, Lebin Chen, Yuanyuan Ji, Liqun Jiao   +15 more
wiley   +1 more source

Cholesteryl ester synthesis in macrophages: stimulation by beta-very low density lipoproteins from cholesterol-fed animals of several species

Journal of Lipid Research, 1980
Animals fed cholesterol accumulate several types of cholesterol-rich lipoproteins in their plasma and ultimately develop cholesteryl ester deposition in tissue macrophages.
R W Mahley, T L Innerarity, M S Brown, Y K Ho, J L Goldstein   +4 more
doaj  

Obesity‐related glomerulopathy: How it happens and future perspectives

Diabetic Medicine, Volume 42, Issue 6, June 2025.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey, Jia‐Kai Tan, Zhan‐Foong Lim, Francesco Zaccardi, Kamlesh Khunti, Majid Ezzati, Edward W. Gregg, Lee‐Ling Lim   +7 more
wiley   +1 more source

Studies on plasma lipoproteins during absorption of exogenous lecithin in man.

Journal of Lipid Research, 1980
Human subjects were infused intraduodenally with either lecithin (150 mg/kg/hr) or safflower oil (100 mg/kg/hr)of similar fatty acid composition, and plasma lipoproteins were studied when constant plasma lipid levels were reached.
F U Beil, S M Grundy
doaj  

Softness and Hydrodynamic Interactions Regulate Lipoprotein Transport in Crowded Yolk Environments [PDF]

arXiv
Low-density lipoproteins (LDLs) serve as nutrient reservoirs in egg yolk for embryonic development and as promising drug carriers. Both roles critically depend on their mobility in densely crowded biological environments. Under these crowded conditions, diffusion is hindered by transient confinement within dynamic cages formed by neighboring particles,
arxiv  

Metabolomic network reveals novel biomarkers for type 2 diabetes mellitus in the UK Biobank study

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3335-3346, June 2025.
Abstract Aims To identify hub metabolic biomarkers that constructively shape the type 2 diabetes mellitus (T2DM) risk network. Materials and Methods We analysed data from 98 831 UK Biobank participants, confirming T2DM diagnoses via medical records and International Classification of Diseases codes.
Jiahao Liu, Xianwen Shang, Xueli Zhang, Yutong Chen, Beiou Zhang, Wentao Tang, Li Li, Ruiye Chen, Catherine Jan, Wenyi Hu, Mayinuer Yusufu, Yujie Wang, Zhuoting Zhu, Mingguang He, Lei Zhang   +14 more
wiley   +1 more source

Effect of dietary cholesterol level on the composition of thoracic duct lymph lipoproteins isolated from nonhuman primates

Journal of Lipid Research, 1983
The effect of two different levels of dietary cholesterol (0.16 mg/Kcal and 0.79 mg/cal) on the composition of thoracic lymph duct lipoproteins was studied in two species of nonhuman primates, Ceropithecus aethiops (African green monkey) and Macaca ...
R L Klein, L L Rudel
doaj  

Oppositely biased glucagon‐like peptide‐1 receptor agonism does not differentially affect lipid metabolism in APOE*3‐Leiden CETP mice

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3477-3489, June 2025.
Abstract Aims [D3,G40,K41.C16 diacid]exendin‐4 (acyl‐ExD3) and [F1,G40,K41.C16 diacid]exendin‐4 (acyl‐ExF1) are oppositely biased glucagon‐like peptide‐1 (GLP‐1) receptor agonists that preferentially promote β‐arrestin recruitment or G protein‐induced signalling, respectively.
Melanie Modder, Alejandra Tomas, Salwa Afkir, Amanda C. M. Pronk, Trea C. M. Streefland, Reshma A. Lalai, Robin van Eenige, Patrick C. N. Rensen, Ben Jones, Sander Kooijman   +9 more
wiley   +1 more source

Regulation of lipid transfer between lipoproteins by an endogenous plasma protein: selective inhibition among lipoprotein classes.

Journal of Lipid Research, 1994
Lipid transfer protein (LTP) remodels plasma lipoproteins by promoting mass transfers of cholesteryl ester (CE) and triglyceride between lipoproteins.
R E Morton, D J Greene
doaj  

Meal timing, nutritional status and diet quality in a group of Spanish children

Pediatric Obesity, Volume 20, Issue 6, June 2025.
Summary Introduction Some studies suggest that meal timing is involved in obesity and metabolic health. However, little is known about children, so the aim was to assess whether meal timing patterns affect nutritional status and diet quality in children. Methods A cross‐sectional study was conducted on 880 children (8–13 years).
María Dolores Salas‐González, Viviana Loria‐Kohen, Aránzazu Aparicio, Laura M. Bermejo, Esther Cuadrado‐Soto, Liliana Guadalupe González‐Rodríguez, María del Carmen Lozano‐Estevan, África Peral‐Suárez, Adrián Cervera‐Muñoz, Rosa M. Ortega, Ana M. López‐Sobaler   +10 more
wiley   +1 more source