Results 171 to 180 of about 284,504 (254)

Distinct patterns of lipoproteins with apoB defined by presence of apoE or apoC-III in hypercholesterolemia and hypertriglyceridemia

Journal of Lipid Research, 2001
Apolipoprotein (apo) E and apoC-III concentrations in VLDL and LDL are associated with coronary heart disease. We studied the relationship between apoE and apoC-III and the abnormal concentrations and distribution of apoB lipoproteins in 10 ...
Hannia Campos, Dan Perlov, Christina Khoo, Frank M. Sacks   +3 more
doaj  

Severe insulin‐deficient diabetes is at the opposite end of the neuropathy spectrum to mild aged‐related diabetes

Journal of Diabetes Investigation, Volume 16, Issue 6, Page 1045-1049, June 2025.
ABSTRACT The effect of diabetes subtypes on neuropathy prevalence and metabolic drivers of this relationship are unknown. Using electronic medical records from 50 diabetes care centers in eight states of India with biothesiometer and complete phenotyping data on 22,348 patients, we determined neuropathy prevalence stratified by India‐specific diabetes ...
Brian C Callaghan, Ranjit Mohan Anjana, Lavanya Muthukumar, Evan L Reynolds, Jebarani Saravanan, Mani Arun Vignesh, Aswin Mukundan, Eva L Feldman, Viswanathan Mohan   +8 more
wiley   +1 more source

Regulation of plasma lecithin:cholesterol acyltransferase in man. III. Role of high density lipoprotein cholesteryl esters in the activating effect of a high-fat test meal.

Journal of Lipid Research, 1979
Plasma lecithin:cholesterol acyltransferase (LCAT) activity is increased during the clearance phase of alimentary lipemia induced by a high-fat test meal in normal subjects.
H G Rose, J Juliano
doaj  

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

Journal of Internal Medicine, Volume 297, Issue 6, Page 584-607, June 2025.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca, John D. Henderson, Juleen R. Zierath   +2 more
wiley   +1 more source

Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels

Journal of Lipid Research, 2009
Apolipoprotein AV (apoAV) overexpression causes a decrease in plasma triglyceride (TG) levels, while deficiency of apoAV causes hypertriglyceridemia in both men and mice.
S.F.C. Vaessen, G.M. Dallinga-Thie, C.J.D. Ross, L.J. Splint, L.W. Castellani, P.C.N. Rensen, M.R. Hayden, F.G. Schaap, J.A. Kuivenhoven   +8 more
doaj  

Human luteinized granulosa cells secrete apoB100-containing lipoproteins

Journal of Lipid Research, 2010
Thus far, liver, intestine, heart, and placenta have been shown to secrete apolipoprotein (apo)B-containing lipoproteins. In the present study, we first investigated lipoproteins in human follicular fluid (FF), surrounding developing oocytes within the ...
Thomas Gautier, Steffi Becker, Véronique Drouineaud, Franck Ménétrier, Paul Sagot, Jerzy-Roch Nofer, Sören von Otte, Laurent Lagrost, David Masson, Uwe J.F. Tietge   +9 more
doaj  

ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan

Journal of Lipid Research, 2002
Retention of apolipoprotein (apo)B and apoE-containing lipoproteins by extracellular vascular proteoglycans is critical in atherogenesis. Moreover, high circulating apoC-III levels are associated with increased atherosclerosis risk.
Katherine Olin-Lewis, Ronald M. Krauss, Michael La Belle, Patricia J. Blanche, P.Hugh R. Barrett, Thomas N. Wight, Alan Chait   +6 more
doaj  

High density lipoprotein-induced cardiac prostacyclin synthesis in vitro: relationship to cardiac arachidonate mobilization.

Journal of Lipid Research, 1988
The objectives of this study were to characterize the effects of plasma lipoproteins on prostacyclin (PGI2) production by the Langendorff-perfused rabbit heart, and to determine the mechanism of lipoprotein-induced cardiac PGI2 production.
W A Van Sickle, H G Wilcox, K U Malik, A Nasjletti   +3 more
doaj  

Increased concentration of plasma cholesteryl ester transfer protein in nephrotic syndrome: role in dyslipidemia.

Journal of Lipid Research, 1992
Hyperlipidemia is a prominent feature of the nephrotic syndrome. Lipoprotein abnormalities include increased very low and low density lipoprotein (VLDL and LDL) cholesterol and variable reductions in high density lipoprotein (HDL) cholesterol.
P Moulin, GB Appel, HN Ginsberg, AR Tall
doaj  

Measurement of cholesterol of major serum lipoprotein classes by anion-exchange HPLC with perchlorate ion-containing eluent

Journal of Lipid Research, 2003
We have developed a high-performance liquid chromatography (HPLC) method for measurement of cholesterol in the major classes of serum lipoproteins, i.e., HDL, LDL, IDL, VLDL, and chylomicrons.
Yuji Hirowatari, Hiroshi Yoshida, Hideo Kurosawa, Ken-iti Doumitu, Norio Tada   +4 more
doaj