Results 21 to 30 of about 20,742 (150)

Ex VivoMeasurement of Lipoprotein Lipase-Dependent Very Low Density Lipoprotein (VLDL)-Triglyceride Hydrolysis in Human VLDL: An Alternative to the Postheparin Assay of Lipoprotein Lipase Activity?¹ [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2001
The plasma lipolysis of triglyceride (TG)-rich lipoproteins is mainly due to the activity of lipoprotein lipase (LPL). Albeit important for our analysis of certain physiopathological situations, the determination of the magnitude of LPL-dependent lipolysis is not easy to perform.
Bruno Vergès, Gabriel Ponsin, Francois Berthezene, Laurence Duvillard, Delphine Autran, Christophe Marçais, Philippe Moulin, Valerie Pruneta   +7 more
openaire   +3 more sources

Phospholipids in lipoproteins: compositional differences across VLDL, LDL, and HDL in pregnant women [PDF]

Lipids in Health and Disease, 2019
The aim of this study was to analyse the differences in the phospholipid composition of very low density (VLDL), low density (LDL) and high density lipoprotein (HDL) monolayers in pregnant lean and obese women.LDL, HDL, and VLDL were isolated from plasma samples of 10 lean and 10 obese pregnant women, and their species composition of ...
Olaf Uhl, José E. Blanco-Carnero, María T. Prieto-Sánchez, Franca F. Kirchberg, Hans Demmelmair, Elvira Larqué, Aníbal Nieto, Antonio Gázquez, Antonio Gázquez, Berthold Koletzko, María Ruiz-Palacios, Sebastian Rauschert   +11 more
openaire   +5 more sources

Proteomic Analysis of the Very Low Density Lipoprotein (VLDL) transport vesicles [PDF]

Journal of Proteomics, 2012
The VLDL transport vesicle (VTV) mediates the transport of nascent VLDL particles from the ER to the Golgi and plays a key role in VLDL-secretion from the liver. The functionality of VTV is controlled by specific proteins; however, full characterization and proteomic profiling of VTV remain to be carried out. Here, we report the first proteomic profile
Riyaz Basha, Abdul Rahim, Shaila Siddiqi, Erika Nafi-valencia, Chukwuemeka C. Runyon, Shadab A. Siddiqi   +5 more
openaire   +4 more sources

The Very Low-density Lipoprotein (VLDL) Receptor: Characterization and Functions as a Peripheral Lipoprotein Receptor

Journal of Atherosclerosis and Thrombosis, 2004
The very low-density lipoprotein (VLDL) receptor is a member of the low-density lipoprotein (LDL) receptor family. In vitro and in vivo studies have shown that VLDL receptor binds triglyceride (TG)-rich lipoproteins but not LDL, and functions as a peripheral remnant lipoprotein receptor.
Tokuo T. Yamamoto, Jinya Suzuki, Yasuo Zenimaru, Takahiro Fujino, Takahiro Fujino, Hiroaki Hattori, Isamu Miyamori, Juro Sakai, Sadao Takahashi   +8 more
openaire   +4 more sources

Deficiency of the Very Low-Density Lipoprotein (VLDL) Receptors in Streptozotocin-Induced Diabetic Rats: Insulin Dependency of the VLDL Receptor [PDF]

Endocrinology, 2005
AbstractHyperlipidemia is a common feature of diabetes and is related to cardiovascular disease. The very low-density lipoprotein receptor (VLDL-R) is a member of the low-density lipoprotein receptor (LDL-R) family. It binds and internalizes triglyceride-rich lipoproteins with high specificity.
Masao Takahashi, Makoto Nagano, Hironobu Naiki, Norman E. Miller, Hiroaki Hattori, Takahiro Fujino, Tokuo T. Yamamoto, Sadao Takahashi, Takeshi Kujiraoka, Juro Sakai, Mitsuaki Ishihara, Yasuo Zenimaru, Jinya Suzuki, Tadao Iwasaki, Isamu Miyamori   +14 more
openaire   +3 more sources

The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor. [PDF]

Journal of Clinical Investigation, 1997
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity has not been elucidated, but likely involves both its ability to influence plasminogen activation as well as its atherogenic potential as a lipoprotein particle after receptor-mediated uptake.
Karen Kozarsky, John T. Fallon, Kelley M. Argraves, Dudley K. Strickland, Peter C. Harpel   +4 more
openaire   +3 more sources

Very Low Density Lipoprotein (VLDL) Receptor-deficient Mice Have Reduced Lipoprotein Lipase Activity [PDF]

Journal of Biological Chemistry, 2002
Although very low density lipoprotein (VLDL) receptor (VLDLr) knockout mice have been reported to have no lipoprotein abnormalities, they develop less adipose tissue than control mice when fed a high calorie diet. Mice that are deficient in adipose tissue expression of lipoprotein lipase (LpL) also have less fat, but only when crossed with ob/ob mice ...
Sungshin Y. Choi, E. Peer Lutz, André Bensadoun, Yuko Kako, Hiroaki Yagyu, Yunying Hu, Ira J. Goldberg, Steven A. Marks   +7 more
openaire   +3 more sources

Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL [PDF]

Journal of Lipid Research, 1998
Mouse and hamster SR-BI glycoproteins and their putative human counterpart CLA-I are so far the only scavenger receptors known to bind both native and modified lipoproteins. CD36, a multigland glycoprotein structurally related to SR-BI and CLA-1, has been reported to bind oxidized low density lipoprotein (OxLDL) and acetylated LDL (AcLDL).
Miguel A. Vega, Miguel A. Lasunción, Diego Gómez-Coronado, Yajaira Suárez, Dominica Calvo   +4 more
openaire   +4 more sources

VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2020
Objective: To clarify the association between PCSK9 (proprotein convertase subtilisin/kexin type 9) and Lp(a) (lipoprotein [a]), we studied Lp(a) kinetics in patients with loss-of-function and gain-of-function PCSK9 mutations and in patients in whom extended-release niacin reduced Lp(a)
Croyal, Mikaël, Blanchard, Valentin, Ouguerram, Khadija, Chétiveaux, Maud, Cabioch, Léa, Moyon, Thomas, Billon-Crossouard, Stéphanie, Aguesse, Audrey, Bernardeau, Karine, Le May, Cedric, Flet, Laurent, Lambert, Gilles, Hadjadj, Samy, Cariou, Bertrand, Krempf, Michel, Nobécourt-Dupuy, Estelle   +15 more
openaire   +9 more sources

Membrane receptors for very low density lipoprotein (VLDL) inhibitor of lymphocyte proliferation [PDF]

Blood, 1981
Abstract Physiologic concentrations of human plasma very low density lipoproteins inhibit the DNA synthesis of lymphocytes stimulated by allogeneic cells or lectins. In this report we have compared the effects of isolated lipoproteins [very low density lipoproteins (VLDL), low density lipoproteins (LDL), and high density lipoproteins ...
P.I. Yi, Stanley Zucker, G. Beck
openaire   +4 more sources