Results 71 to 80 of about 45,302 (266)
Advanced Science, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy +8 more
wiley +1 more source
Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance [PDF]
Trends in Endocrinology & Metabolism, 2011 Insulin resistance (IR) affects not only the regulation of carbohydrate metabolism but all aspects of lipid and lipoprotein metabolism. IR is associated with increased secretion of VLDL and increased plasma triglycerides, as well as with hepatic steatosis, despite the increased VLDL secretion.
Sung Hee, Choi, Henry N, Ginsberg
openaire +2 more sources
Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis
Animal Models and Experimental Medicine, EarlyView.This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding +10 more
wiley +1 more source
Journal of Lipid Research, 1980 Because we found apoprotein contamination of some high-grade commercial albumins, we studied this effect on formation of lipoprotein-like particles during lipolysis of human very low density lipoprotein (VLDL) in vitro.
R J Deckelbaum, T Olivecrona, M Fainaru
doaj +1 more source
A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats
Animal Models and Experimental Medicine, EarlyView.Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies +3 more
wiley +1 more source
Journal of Lipid Research, 1987 Perfusate apoB-100-containing lipoproteins from the isolated, perfused livers of African green monkeys consist of significant amounts of d greater than 1.006 g/ml particles in addition to very low density lipoproteins (VLDL).
F L Johnson, L L Swift, L L Rudel
doaj +1 more source
Journal of Lipid Research, 1987 The aim of this study was to determine the effect of oleic acid and insulin on the secretion of lipoproteins by HepG2 cells grown in minimum essential medium.
N Dashti, G Wolfbauer
doaj +1 more source
Ferritin heavy chain Is the host factor responsible for HCV-Induced inhibition of apoB-100 production and is required for efficient viral infection [PDF]
, 2012 Hepatic fat export occurs by apolipoprotein B-100-containing lipoprotein production, whereas impaired production leads to liver steatosis. Hepatitis C virus (HCV) infection is associated to dysregulation of apoB-100 secretion and steatosis; however, the ...
AMICONE, Laura +9 more
core +3 more sources
Interaction of cholesterol ester and triglyceride in human plasma very low density lipoprotein1
Journal of Lipid Research, 1977 The properties of human plasma very low density lipoproteins (VLDL), low density lipoproteins (LDL), and their extracted lipids were compared using calorimetric, X-ray scattering, and polarizing microscopy techniques.
R J Deckelbaum, A R Tall, D M Small
doaj +1 more source
Triglyceride-rich lipoproteins prevent septic death in rats. [PDF]
, 1995 Triglyceride-rich lipoproteins bind and inactive bacterial endotoxin in vitro and prevent death when given before a lethal dose of endotoxin in animals.
Calhoun, MC +6 more
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