Results 91 to 100 of about 191,701 (337)
The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility
Abstract Background Ischemic stroke (IS), a multifactorial and polygenic disease, is the most common cause of death. This study aimed to determine the roles of MMP8/MMP10 polymorphisms in IS susceptibility in the Chinese Han population. Methods MMP8 rs1940475 and rs3765620, and MMP10 rs17860949 from 700 IS patients and 700 controls were genotyped by ...
Yong Zhao+11 more
wiley +1 more source
Olive oil intake in relation to cardiovascular diseases
Atherosclerosis is the principal contributor to the pathogenesis of coronary artery disease (CAD). Epidemiological, clinical and metabolic studies have reported protective associations between (extra virgin) olive oil consumption and CAD.
Antonis Zampelas, Anthony G. Kafatos
doaj +1 more source
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu+13 more
wiley +1 more source
Lipid metabolism in pancreatic cancer: emerging roles and potential targets
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin+6 more
wiley +1 more source
In this work, we determined the content of antibodies to low-density lipoproteins modified by malondialdehyde, the concentration of circulating immune complexes cholesterol and oxidized low-density lipoproteins in the blood of healthy individuals and ...
A. A. Ivanova+2 more
doaj +1 more source
O objetivo deste trabalho foi avaliar o efeito de bixina do colorífico e niacina suplementar em rações, nos níveis plasmáticos de triglicerídeos e lipoproteínas de densidade muito baixa, na gordura da carne de peito, de coxa e sobrecoxa, e na carcaça de ...
Newton Tavares Escocard de Oliveira+3 more
doaj +1 more source
Blood lipoproteins shape the phenotype and lipid content of early atherosclerotic lesion macrophages: a dual-structured mathematical model [PDF]
Macrophages in atherosclerotic lesions exhibit a spectrum of behaviours or phenotypes. The phenotypic distribution of monocyte-derived macrophages (MDMs), its correlation with MDM lipid content, and relation to blood lipoprotein densities are not well understood.
arxiv
Regression Discontinuity Designs: A Decision Theoretic Approach [PDF]
The regression discontinuity design (RDD) is a quasi-experimental design that can be used to identify and estimate the causal effect of a treatment using observational data. In an RDD, a pre-specified rule is used for treatment assignment, whereby a subject is assigned to the treatment (control) group whenever their observed value of a specific ...
arxiv
Electrophoresis and Monomolecular Layer Studies with Serum Lipoproteins [PDF]
D. Adlersberg+3 more
openalex +1 more source
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi+13 more
wiley +1 more source