Results 111 to 120 of about 161,796 (303)

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Lipids and lipoproteins

, 2023
Lipids are essential in human physiology, triglycerides for energy and cholesterol as a structural component in cells and as a precurser for hormones and vitamins.
Nordestgaard, Børge G, Wulff, Anders Berg   +1 more
core   +1 more source

Effect of diet on the cholesterol ester composition of liver and of plasma lipoproteins in the rat

Journal of Lipid Research, 1965
The relationship between the cholesterol ester composition of the liver and the plasma lipoproteins was studied in groups of rats maintained for 5–11 weeks on the following diets: (I) rat pellets, (II) rat pellets with added olive oil and cholesterol ...
Lewis I. Gidez, Paul S. Roheim, Howard A. Eder   +2 more
doaj   +1 more source

Controllable Cascade Aggregation Ion Programmed Nanomachines and Simple Isolation Enable Tumor‐Derived Small Extracellular Vesicles Detection for Enhanced Breast Cancer Assessment

Advanced Science, EarlyView.
This study developed a convenient, enzyme‐free detection platform based on controllable aggregation ion nanomachines. Its favorable anti‐interference capacity and high sensitivity meet the detection requirements for clinical samples processed via a simple filtration method within 10 min.
Zhihao Zhang, Zijing Liu, Xiangyue Meng, Pengjun Jiang, Jie Qu, Yu Jiang, Binxu Qiu, Jie Chen, Piaopiao Chen   +8 more
wiley   +1 more source

IMMUNOGENETICS OF RABBIT LOW-DENSITY LIPOPROTEINS.

, 1969
IMMUNOGENETICS OF RABBIT LOW-DENSITY ...
JOHN JOSEPH. ALBERS (7974092)
core   +3 more sources

Analyzing the molecular mechanism of lipoprotein localization in Brucella

Frontiers in Microbiology, 2015
Bacterial lipoproteins possess comprehensive structure and functionality, ranging from bacterial physiology to pathogenic processes. As such many lipoproteins, originating from Brucella are exploited as potential vaccines to countermeasure brucellosis ...
Shivani eGoolab, Shivani eGoolab, Robyn Lindsay Roth, Henriette evan Heerden, Michael Craig Crampton   +4 more
doaj   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Antibodies to low-density lipoproteins modified by malonic dialdehyde: contents in blood and role in atherogenesis

Медицинская иммунология
In this work, we determined the content of antibodies to low-density lipoproteins modified by malondialdehyde, the concentration of circulating immune complexes cholesterol and oxidized low-density lipoproteins in the blood of healthy individuals and ...
A. A. Ivanova, A. A. Dmitrieva, A. D. Denisenko   +2 more
doaj   +1 more source

Lipoprotein(a) [PDF]

Clinical Research in Cardiology Supplements, 2019
K P, Mellwig, A, Vogt
openaire   +2 more sources