Results 151 to 160 of about 209,402 (307)
Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver
It has been proposed that particles within tubules and vesicles of the Golgi apparatus of liver cells are precursors of very low density lipoproteins in blood plasma. To characterize these particles we isolated a cell fraction rich in Golgi apparatus and
Robert W. Mahley+2 more
doaj
Lipoprotein(a): The Renaissance of an Enigmatic Lipoprotein [PDF]
openaire +4 more sources
Lp(a) is a genetically determined, heritable, independent and causal risk factor for ASCVD. About 1 in 5 people worldwide have elevated Lp(a) (>50 mg/dL or >125 nmol/L) whereas in Indians it is 25 %. Epidemiological, genome-wide association and mendelian randomization studies have demonstrated an association between elevated Lp(a) levels and increased ...
openaire +3 more sources
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang+9 more
wiley +1 more source
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun+15 more
wiley +1 more source
Lipid Metabolism and Comparative Genomics [PDF]
Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette+5 more
core
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge+10 more
wiley +1 more source
A method to measure apolipoprotein B radioactivity in whole blood plasma is described that is suitable for routine use in kinetic experiments in vivo.
N Yamada, R J Havel
doaj
THE α2 LIPOPROTEINS OF HUMAN SERUM. CORRELATION OF ULTRACENTRIFUGAL AND ELECTROPHORETIC PROPERTIES [PDF]
Henry G. Kunkel, Rodes Trautman
openalex +1 more source
Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li+11 more
wiley +1 more source