Results 171 to 180 of about 319,032 (338)

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

open access: yesAdvanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang   +14 more
wiley   +1 more source

Electrophoresis and Monomolecular Layer Studies with Serum Lipoproteins

open access: bronze, 1955
D. Adlersberg   +3 more
openalex   +1 more source

EFFECT OF THE LEVEL AND TYPE OF DIETARY FAT ON THE METABOLISM OF CHOLESTEROL AND BETA LIPOPROTEINS IN THE CEBUS MONKEY [PDF]

open access: bronze, 1956
Oscar W. Portman   +5 more
openalex   +1 more source

Microglia Drive Peripapillary Vascular Density Reduction in Normal Tension Glaucoma by Regulating the Rpl17/Stat5b/Apoa1 Axis

open access: yesAdvanced Science, EarlyView.
This study revealed that E50K mutant microglia drive retinal peripapillary vascular density reduction in NTG via the Rpl17/Stat5b/Apoa1 axis and identified Apoa1 as a novel suppressor of retinal vascular endothelial cells. These findings identify a potential therapeutic target for glaucoma and support the clinical potential of EA for protecting RGCs ...
Di Zhang   +9 more
wiley   +1 more source

Influence of Lipoprotein on the Freezing of Bovine Spermatozoa

open access: bronze, 1957
G. Bialy   +3 more
openalex   +1 more source

Distribution and transfer of cyclosporine among the various human lipoprotein classes [PDF]

open access: yes, 1983
Graf, A.   +7 more
core   +1 more source

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

open access: yesAdvanced Science, EarlyView.
A peptide that replicates the amino acid sequence in Insig1/2 loop 1 inhibits the IGF1‐induced interaction between PCK1 and Insig1/2, PCK1‐mediated phosphorylation of Insig1/2, and SREBP activity‐dependent lipid synthesis. Administration of the LNP‐Insig1/2 loop 1 peptide effectively attenuates tumor growth and sensitizes tumors to the antitumor effect
Shudi Luo   +10 more
wiley   +1 more source

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