Results 81 to 90 of about 191,701 (337)
Advanced Science, EarlyView.This work proposes a novel strategy targeting gut microbiota for managing polycystic ovary syndrome (PCOS). Inulin, a gut microbiota modulator, notably boosts the growth of short‐chain fatty acids (SCFAs)‐producers, represented by Bifidobacterium, thereby improving glucolipid metabolism and ovarian function of PCOS through suppressing the inflammatory ...
Lulu Geng +8 more
wiley +1 more source
Journal of Lipid Research, 1984 Hypercholesterolemia, induced by a cholesterol-enriched diet, is associated with distinctive modifications in the serum lipoproteins of a variety of species.
L L Swift +3 more
doaj
Advanced Science, EarlyView.This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang +13 more
wiley +1 more source
Large lipoproteins are excluded from the arterial wall in diabetic cholesterol-fed rabbits
Journal of Lipid Research, 1988 In diabetic hypercholesterolemic rabbits at plasma triglyceride concentrations of approximately 5000 mg/dl, 55% of plasma cholesterol (1400 mg/dl) was in lipoproteins with diameters larger than 75 nm (Sf greater than 400), 40% in smaller very low density
B G Nordestgaard, D B Zilversmit
doaj
Structured functional regression models for high-dimensional spatial spectroscopy data [PDF]
arXiv, 2013 Modeling and analysis of spectroscopy data is an active area of research with applications to chemistry and biology. This paper focuses on analyzing Raman spectra obtained from a bone fracture healing experiment, although the functional regression model for predicting a scalar response from high-dimensional tensors can be applied to any spectroscopy ...
arxiv
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
Advanced Science, EarlyView.The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari +20 more
wiley +1 more source
Journal of Lipid Research, 1975 The simultaneous exchange of (3h)tocopherol and (14C)cholesterol between rat plasma, rat plasma lipoproteins, and RBC was studied in vitro to compare quantitavely (a) the fractional exchange rates and (b) the half-times for isotope equilibration.
L.K. Bjornson +2 more
doaj
The giant low-density lipoproteins (LDL) accumulation in the multi-layer artery wall model [PDF]
arXiv, 2014 The mathematical, four-layer model of the LDL transport across the arterial wall including the sensitivity of the transport coefficients to the wall shear stress (WSS) is studied. In that model the advection-diffusion equations in porous media are used to determine the LDL concentration profiles in each layer of the arterial wall.
arxiv
An Investigation of Serum Lipids and Lipoproteins by Paper Electrophoresis [PDF]
, 1955 W. G. Dangerfield, ElspethB. Smith
openalex +1 more source
Advanced Science, EarlyView.A model is schematically represented for the major molecular mechanisms by which homocysteine (Hcy) accelerates the nuclear export of circ‐PIAS1‐5, which regulates atherosclerosis by acting as a competing endogenous RNA for miR‐219a‐2‐3p. Hcy enrichment of circ‐PIAS1‐5 leads to YTHDC1 binding to circ‐PIAS1‐5 and promotes its intracellular localization ...
Shengchao Ma +13 more
wiley +1 more source