Results 71 to 80 of about 13,126,675 (165)

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 10, Page 1648-1661, October 2026.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Pharmacodynamic Effects of Simulated Standard Doses of Antifungal Drugs against Aspergillus Species in a New In Vitro Pharmacokinetic/Pharmacodynamic Model [PDF]

, 2011
In conventional MIC tests, fungi are exposed to constant drug concentrations, whereas in vivo, fungi are exposed to changing drug concentrations.
Thomas J. Walsh, Emmanuel Roilides, Aristea Velegraki, Walsh, Thomas, Zerva, Loukia, Meletiadis, Joseph, Joseph Meletiadis, Roilides, Emmanuel, Rafal Al-Saigh, Velegraki, Aristea, Loukia Zerva, Al Saigh, Rafal   +11 more
core   +1 more source

Successful Management of Sequential Pulmonary Infections in a Cardiac Transplant Recipient

Canadian Journal of Infectious Diseases, 1990
A case of a cardiac allograft recipient who had an initial combined pulmonary infection with cytomegalovirus, Aspergillus fumigatus and Nocardia asteroides, successfully treated with liposomal amphotericin B and sulfisoxazole and followed by an episode ...
John Galbraith, Jutta K Preiksaitis, Sandra Czekanski, Mark J Poznansky, Mohamed Hirji   +4 more
doaj   +1 more source

Perillic Acid Synergizes With the Miltefosine Leishmanicidal Effect Against Leishmania amazonensis

Parasite Immunology, Volume 48, Issue 10, October 2026.
ABSTRACT Perillic acid (PA), a monocyclic monoterpene derived from limonene, was evaluated for its leishmanicidal activity alone and in combination with miltefosine, as well as in its microemulsion‐based formulation. PA demonstrated synergistic activity with miltefosine and was effective against both promastigote and amastigote forms of Leishmania ...
C. Ferreira, M. Paschoal, C. L. A. Passos, K. G. H. Silva, K. C. H. Silva, E. M. Saraiva, D. C. Soares   +6 more
wiley   +1 more source

Increasing incidence of mucormycosis in a large Spanish hospital from 2007 to 2015: Epidemiology and microbiological characterization of the isolates.

PLoS ONE, 2017
We studied 19 cases of proven/probable mucormycosis diagnosed from 2007 to 2015 in our hospital and assessed the microbiological characteristics of the isolates.
Jesús Guinea, Pilar Escribano, Antonio Vena, Patricia Muñoz, María Del Carmen Martínez-Jiménez, Belén Padilla, Emilio Bouza   +6 more
doaj   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Ultra-performance liquid chromatography for quantification of amphotericin B plasma concentrations after use of liposomal amphotericin B

, 2020
OBJECTIVES: Liposomal amphotericin B is widely used to treat life-threatening invasive fungal infections and has replaced conventional amphotericin B deoxycholate due to its more favourable toxicity profile. Despite the fact that liposomal amphotericin B
Daele, R. Van, Bruggemann, Roger J., Brüggemann, R.J.M., Spriet, Isabel, Van Daele, Ruth, Maertens, J., de Beer, Yvo, Aarnoutse, Rob, Maertens, Johan, Beer, Y. de, Wauters, J., Croes, S., Aarnoutse, R.E., Spriet, I., Croes, Sander, Wauters, Joost, Roger J Brüggemann, Isabel Spriet, Joost Wauters, Johan Maertens, Rob Aarnoutse, Sander Croes, Yvo de Beer, Ruth Van Daele   +23 more
core   +1 more source

Comparison between liposomal formulations of amphotericin B

, 2016
International audienceGiven the clinical success of commercial amphotericin B lipid products, investigators have begun making generic formulations of liposomal amphotericin B.
Adler-Moore, Jill P., Gangneux, Jean-Pierre, Pappas, Peter G   +2 more
core   +1 more source

High-dose amphotericin: yay or nay? A case series and literature review

Drugs in Context
Invasive fungal infections pose significant morbidity and mortality risks, particularly those caused by moulds. Available antifungal classes are limited by toxicities and are increasingly susceptible to resistance, particularly amongst challenging fungal
Kayla R Stover, Taylor E Jordan, Jamie L Wagner, Katie E Barber   +3 more
doaj   +1 more source

Development and deployment of a solid oral amphotericin B dosage form to treat visceral leishmaniasis within a pediatric population.

PLoS Neglected Tropical Diseases
Visceral leishmaniasis (VL) is a severe and potentially fatal infection, with over 90% of reported cases occurring in East African countries including Chad, Djibouti, Eritrea, Ethiopia, Kenya, Somalia, South Sudan, Sudan, and Uganda, affecting mainly ...
Kishor M Wasan
doaj   +1 more source