Results 11 to 20 of about 183,250 (346)

Encapsulation of Bacteriophage in Liposome Accentuates Its Entry in to Macrophage and Shields It from Neutralizing Antibodies. [PDF]

PLoS ONE, 2016
Phage therapy has been a centre of attraction for biomedical scientists to treat infections caused by drug resistant strains. However, ability of phage to act only on extracellular bacteria and probability of interference by anti-phage antibodies in vivo
Saloni Singla, Kusum Harjai, Om Prakash Katare, Sanjay Chhibber   +3 more
doaj   +2 more sources

A Case Report of Subcutaneously Injected Liposomal Cannabidiol Formulation Used as a Compassion Therapy for Pain Management in a Dog

Frontiers in Veterinary Science, 2022
A 14-year-old intact mixed breed dog (26 kg) was submitted for a novel cannabidiol (CBD) analgesic treatment. The dog was cachectic and had a testicular neoplasia, hip and elbow osteoarthritis and severe cervical pain. Analgesic treatment included canine
Yael Shilo-Benjamini, Yael Shilo-Benjamini, Ahuva Cern, Daniel Zilbersheid, Atara Hod, Eran Lavy, Dinorah Barasch, Yechezkel Barenholz   +7 more
doaj   +1 more source

Therapeutic efficacy and pharmacokinetics of liposomal-cannabidiol injection: a pilot clinical study in dogs with naturally-occurring osteoarthritis

Frontiers in Veterinary Science, 2023
IntroductionOsteoarthritis is a common disease in dogs resulting in chronic pain and decreased wellbeing. Common analgesics such as non-steroidal anti-inflammatories may fail to control pain and can produce major adverse effects. Study objectives were to
Yael Shilo-Benjamini, Yael Shilo-Benjamini, Eran Lavy, Nadav Yair, Joshua Milgram, Daniel Zilbersheid, Atara Hod, Dinorah Barasch, Wiessam Abu Ahmad, Ahuva Cern, Yechezkel Barenholz   +10 more
doaj   +1 more source

TLC599 in patients with osteoarthritis of the knee: a phase IIa, randomized, placebo-controlled, dose-finding study

Arthritis Research & Therapy, 2022
Background Corticosteroid injection for knee osteoarthritis is limited by its modest duration of treatment effect. The liposome formulation of dexamethasone sodium phosphate (TLC599) was developed for the sustained relief of osteoarthritis pain.
David J. Hunter, Chi-Ching Chang, James Cheng-Chung Wei, Hsiao-Yi Lin, Carl Brown, Tien-Tzu Tai, Chih-Feng Wu, Wing Chia-Ming Chuang, Sheue-Fang Shih   +8 more
doaj   +1 more source

Therapeutic Potential of Injectable Nano-Mupirocin Liposomes for Infections Involving Multidrug-Resistant Bacteria

Pharmaceutics, 2021
Antibiotic resistance is a global health threat. There are a few antibiotics under development, and even fewer with new modes of action and no cross-resistance to established antibiotics.
Ahuva Cern, Yaelle Bavli, Atara Hod, Daniel Zilbersheid, Shazad Mushtaq, Ayelet Michael-Gayego, Dinorah Barasch, Yael Feinstein Rotkopf, Allon E. Moses, David M. Livermore, Yechezkel Barenholz   +10 more
doaj   +1 more source

Advancements in liposome technology: Preparation techniques and applications in food, functional foods, and bioactive delivery: A review.

Comprehensive Reviews in Food Science and Food Safety, 2021
Liposomes play a significant role in encapsulation of various bioactive compounds (BACs), including functional food ingredients to improve the stability of core.
K. K. Ajeeshkumar, P. Aneesh, N. Raju, M. Suseela, C. N. Ravishankar, S. Benjakul   +5 more
semanticscholar   +1 more source

A Strategy to Treat COVID‐19 Disease With Targeted Delivery of Inhalable Liposomal Hydroxychloroquine: A Preclinical Pharmacokinetic Study

Clinical and Translational Science, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a newly identified pathogen causing the coronavirus disease 2019 (COVID‐19) pandemic. Hydroxychloroquine (HCQ), an antimalarial and anti‐inflammatory drug, has been shown to inhibit SARS‐CoV‐
Tien‐Tzu Tai, Tzung‐Ju Wu, Huey‐Dong Wu, Yi‐Chen Tsai, Hui‐Ting Wang, An‐Min Wang, Sheue‐Fang Shih, Yee‐Chun Chen   +7 more
doaj   +1 more source

Recent Advancements in Polymer/Liposome Assembly for Drug Delivery: From Surface Modifications to Hybrid Vesicles

Polymers, 2021
Liposomes are consolidated and attractive biomimetic nanocarriers widely used in the field of drug delivery. The structural versatility of liposomes has been exploited for the development of various carriers for the topical or systemic delivery of drugs ...
V. De Leo, F. Milano, A. Agostiano, L. Catucci   +3 more
semanticscholar   +1 more source

Breaking the Third Wall: Implementing 3D-Printing Techniques to Expand the Complexity and Abilities of Multi-Organ-on-a-Chip Devices

Micromachines, 2021
The understanding that systemic context and tissue crosstalk are essential keys for bridging the gap between in vitro models and in vivo conditions led to a growing effort in the last decade to develop advanced multi-organ-on-a-chip devices.
Yoel Goldstein, Sarah Spitz, Keren Turjeman, Florian Selinger, Yechezkel Barenholz, Peter Ertl, Ofra Benny, Danny Bavli   +7 more
doaj   +1 more source

Post-Processing Techniques for the Improvement of Liposome Stability

Pharmaceutics, 2021
Liposomes have been utilized as a drug delivery system to increase the bioavailability of drugs and to control the rate of drug release at the target site of action.
Ji Young Yu, Piyanan Chuesiang, G. Shin, H. Park   +3 more
semanticscholar   +1 more source