Results 31 to 40 of about 183,250 (346)

What We Need to Know about Liposomes as Drug Nanocarriers: An Updated Review [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2023
Liposomes have been attracted considerable attention as phospholipid spherical vesicles, over the past 40 years. These lipid vesicles are valued in biomedical application due to their ability to carry both hydrophobic and hydrophilic agents, high ...
Hanieh Abbasi   +6 more
doaj   +1 more source

Liposome Deformation Induced by Membrane-Binding Peptides

open access: yesMicromachines, 2023
This paper presents an investigation of liposome deformation and shape distortion using four membrane-binding peptides: TAT and C105Y as cell-penetrating peptides (CPPs), and melittin and ovispirin as antimicrobial peptides (AMPs).
Kayano Izumi   +2 more
doaj   +1 more source

Molecular Dynamics Simulations and Empirical Observations on Soy Lecithin Liposome Preparation

open access: yesIndonesian Journal of Chemistry, 2016
Soy lecithin is a phospholipid often used in liposome formulations. Determination of water and phospholipid composition is one of the problems in the liposome formulation.
Rini Dwiastuti   +4 more
doaj   +1 more source

Simulation of pulsatory liposome working using a linear approximation for transmembrane pore dynamics [PDF]

open access: yesINCAS Bulletin
This paper presents an analytical solution of the differential equations describing the pulsatory liposome dynamics. We consider a unilamellar liposome filled with an aqueous solution of osmotic solute inserted in a hypotonic aqueous medium.
Dumitru POPESCU   +2 more
doaj   +1 more source

Macrophage depletion by clodronate liposome attenuates muscle injury and inflammation following exhaustive exercise

open access: yesBiochemistry and Biophysics Reports, 2016
Exhaustive exercise promotes muscle injury, including myofiber lesions; however, its exact mechanism has not yet been elucidated. In this study, we tested the hypothesis that macrophage depletion by pretreatment with clodronate liposomes alters muscle ...
Noriaki Kawanishi   +4 more
doaj   +1 more source

PEGylated Liposomal Methyl Prednisolone Succinate does not Induce Infusion Reactions in Patients: A Correlation Between in Vitro Immunological and in Vivo Clinical Studies

open access: yesMolecules, 2020
PEGylated nanomedicines are known to induce infusion reactions (IRs) that in some cases can be life-threatening. Herein, we report a case study in which a patient with rare mediastinal and intracardiac IgG4-related sclerosing disease received 8 ...
Yaelle Bavli   +7 more
doaj   +1 more source

Comparison of the adverse event profiles of conventional and liposomal formulations of doxorubicin using the FDA adverse event reporting system. [PDF]

open access: yesPLoS ONE, 2017
Doxorubicin (DOX) is an anthracycline widely used for the treatment of solid and hematological tumors. The aim of this study was to assess the adverse event profiles of conventional DOX and liposomal DOX. This is the first study to evaluate the effect of
Akiho Fukuda   +12 more
doaj   +1 more source

Octanol-assisted liposome assembly on chip

open access: yesNature Communications, 2016
Liposomes are versatile supramolecular assemblies widely used in basic and applied sciences. Here we present a novel microfluidics-based method, octanol-assisted liposome assembly (OLA), to form monodisperse, cell-sized (5–20 μm), unilamellar liposomes ...
S. Deshpande   +3 more
semanticscholar   +1 more source

Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier

open access: yesInternational Journal of Nanomedicine, 2016
This review summarizes articles that have been reported in literature on liposome-based strategies for effective drug delivery across the blood–brain barrier.
D. Vieira, L. Gamarra
semanticscholar   +1 more source

Lipodox® (generic doxorubicin hydrochloride liposome injection): in vivo efficacy and bioequivalence versus Caelyx® (doxorubicin hydrochloride liposome injection) in human mammary carcinoma (MX-1) xenograft and syngeneic fibrosarcoma (WEHI 164) mouse models

open access: yesBMC Cancer, 2017
Background Doxorubicin (DXR) hydrochloride (HCl) liposome injection is an important part of the treatment armamentarium for a number of cancers. With growing needs for affordable and effective anticancer treatments, the development of generics is ...
Vinod Burade   +5 more
doaj   +1 more source

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